Prevalence of human papillomavirus infection in young women receiving the first quadrivalent vaccine dose

摘要

Methods. Participants were 13- to 21-year-old females receiving their first HPV vaccine dose, recruited from an adolescent primary care clinic between June 2008 and June 2010. These data are from the baseline visit of a longitudinal study that was approved by the hospital's institutional review board. Each participant completed a questionnaire assessing sociodemographic factors and behaviors. History of sexual contact was assessed using the following item: "Have you ever had sexual contact with a male or female (by sexual contact we mean genital, skin-to-skin contact only)?" Sexual experience was defined as a response of yes to the following item: "Have you ever had sex with a male or female (by sex we mean vaginal or anal sex)?" Cervicovaginal swabs were self- or clinician-collected and tested for HPV DNA. Logistic regression models were estimated to determine variables associated with HPV infection in sexually experienced and inexperienced females. The outcome measure was infection with 1 or more HPV types.