High serum HCV RNA in chronic hepatitis C patients coinfected with HIV despite successful antiretroviral therapy

Barreiro Pablo; Labarga Pablo; de Mendoza Carmen; Benitez-Gutierrez Laura; Fernandez-Montero Jose V.; Pena Jose M.; Soriano Vicente

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High serum HCV RNA in chronic hepatitis C patients coinfected with HIV despite successful antiretroviral therapy

机译：尽管抗逆转录病毒疗法成功，但合并感染艾滋病毒的慢性丙型肝炎患者血清HCV RNA高

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Background: Baseline serum HCV RNA predicts treatment success in chronic hepatitis C patients. Thresholds at 0.8, 2, 4 and 6 million IU/ml discriminate treatment outcomes using distinct antiviral regimens. Compared to the general population, immunosuppressed individuals exhibit greater viral load values. This has been confirmed in HIV-HCV-coinfected patients, although little is known about the influence of antiretroviral therapy.

机译：背景：基线血清HCV RNA可预测慢性丙型肝炎患者的治疗成功。使用不同的抗病毒方案，阈值分别为0.8、2、4和6百万IU / ml可以区分治疗结果。与普通人群相比，免疫抑制的个体表现出更高的病毒载量值。尽管对抗逆转录病毒疗法的影响知之甚少，但在HIV-HCV感染的患者中已证实了这一点。

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《Antiviral therapy》 |2016年第6期|共6页
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Barreiro Pablo; Labarga Pablo; de Mendoza Carmen; Benitez-Gutierrez Laura; Fernandez-Montero Jose V.; Pena Jose M.; Soriano Vicente;
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正文语种 eng
中图分类治疗学;
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1. High serum HCV RNA in chronic hepatitis C patients coinfected with HIV despite successful antiretroviral therapy [J] . Barreiro Pablo, Labarga Pablo, de Mendoza Carmen, Antiviral therapy . 2016,第6期

机译：尽管抗逆转录病毒疗法成功，但合并感染艾滋病毒的慢性丙型肝炎患者血清HCV RNA高
2. Stability of hepatitis C virus (HCV) RNA levels among interferon-na?ve HIV/HCV-coinfected individuals treated with combination antiretroviral therapy [J] . GrintD., PetersL., ReekieJ., HIV medicine . 2013,第6期

机译：联合抗逆转录病毒疗法治疗的初次感染干扰素的HIV / HCV感染者中丙型肝炎病毒（HCV）RNA水平的稳定性
3. Changes in hepatitis C virus (HCV) viral load and interferon-alpha levels in HIV/HCV-coinfected patients treated with highly active antiretroviral therapy. [J] . Bower WA, Culver DH, Castor D, JAIDS: Journal of acquired immune deficiency syndromes . 2006,第3期

机译：用高效抗逆转录病毒疗法治疗的HIV / HCV合并感染患者中丙型肝炎病毒（HCV）病毒载量和干扰素-α水平的变化。
4. Hepatic Iron Staining in Chronic Hepatitis C Patients With Low Hcv Rna Levels As A Predictive Marker For interferon therapy [C] . Tatsuya Ide, Fuyuhiko Akiyoshi, Michio Sata, Yamaguchi Symposium on Liver Disease . 2003

机译：慢性丙型肝炎患者肝脏染色低HCV RNA水平作为干扰素治疗的预测标志物
5. The Distribution of Change over Time in Metabolic, Inflammatory, and Immune Parameters in HCV-monoinfected and HIV/HCV-coinfected Patients Cured of Hepatitis C Virus by Direct-Acting Antiviral Therapy [D] . Emmanuel, Benjamin. 2018

机译：通过直接作用抗病毒治疗，在HCV-单染料和HCV / HCV / HCV-焦收的患者中的代谢，炎症和免疫参数随时间随时间的分布，通过直接作用抗病毒治疗治愈丙型肝炎病毒
6. Evaluating the Impact of Hepatitis C Virus (HCV) on Highly Active Antiretroviral Therapy–Mediated Immune Responses in HCV/HIV-Coinfected Women: Role of HCV on Expression of Primed/Memory T Cells [O] . Lena Al-Harthi, John Voris, Wenbo Du, -1

机译：评价丙型肝炎病毒（HCV）对高活性抗逆转录病毒疗法介导的HCV / HIV合并感染妇女的免疫反应的影响：HCV在初免/记忆T细胞表达中的作用
7. Stability of hepatitis C virus (HCV) RNA levels among interferon-naïve HIV/HCV-coinfected individuals treated with combination antiretroviral therapy. [O] . Grint D, Peters L, Reekie J, Soriano V, Kirk O, Knysz B, Suetnov O, Lazzarin A, Ledergerber B, Rockstroh JK, Mocroft A, Vullo V, EuroSIDA in EuroCoord (European Coordinating Committee for the Integration of Ongoing Coordination Actions Related to Clinical and Epidemiological HIV Research) 2013

机译：在接受抗逆转录病毒疗法联合治疗的未接受过干扰素的HIV / HCV合并感染个体中，丙型肝炎病毒（HCV）RNA水平的稳定性。

High serum HCV RNA in chronic hepatitis C patients coinfected with HIV despite successful antiretroviral therapy

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