Clinical Study of Ultrasonic Extreme Velocity Imaging Pulse Wave Technique in Carotid Elasticity in Patients with Type II Diabetes Mellitus

摘要

In this study, extreme velocity ultrasonic imaging pulse wave technology was used to detect the main indices of atherosclerosis such as carotid intima-media thickness (IMT) and carotid elasticity, and biochemical indices such as glycated hemoglobin, blood glucose and blood lipids in one hundred twenty 18-60-year-old patients with type II diabetes mellitus (T2DM) and 120 healthy controls. We analyzed the correlations between carotid elasticity, carotid IMT, and a range of biochemical indices. The results indicated that when the carotid IMT in young and middle-aged patients with T2DM was within the normal range (0.56 +/- 0.03 mm), the carotid artery elasticity was abnormal [Pulse wave propagation velocity (PWV)-BS = 7.69 +/- 1.26 m/s; PWV-ES = 8.34 +/- 1.51 m/s; P < 0.05]. Additionally, PWV-BS was positively correlated with age, course of the disease, glycated hemoglobin (HbA1c), and fasting blood glucose (FBG) (r = 0.297, 0.377, 0.369, 0.382), and PWV-ES was positively correlated with age, course of the disease, HbA1c, and FBG (r = 0.318, 0.386, 0.392, 0.339). This finding provides a basis for extreme velocity ultrasonic imaging pulse wave technology to become a new method for the early screening of atherosclerosis in patients with T2DM; this is important for timely clinical intervention in patients with T2DM.