Comparison of comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry and gas chromatography-mass spectrometry for the analysis of tobacco essential oils

摘要

A sample of tobacco essential oil was analyzed using gas chromatography-mass spectrometry (GC/MS) and comprehensive two-dimensional gas chromatography coupled to a time-of-flight mass spectrometry (GC x GC/TOFMS),respectively.In the GC/MS analysis,serially coupled columns were used.By comparing the GC/MS results with GC x GC/TOFMS results,many more components in the essential oil could be found within the two-dimensional separation space of GC x GC.The quantitative determination of components in the essential oil was performed by GC x GC with flame ionization detection (FID),using a method of multiple internal standards calibration.