Lithium Bromide/HBpin: A Mild and Effective Catalytic System for the Selective Hydroboration of Aldehydes and Ketones

摘要

The catalytic hydroboration of aldehydes and ketones with HBpin was examined using simple and commercially available metal salts(Li,Na,and K).Among the tested salts,LiBr(0.5-1.0 mol%)was found to be an efficient catalyst for the hydroboration of various aldehydes and ketones at room temperature.Further,the chemoselective hydroboration of aldehydes over ketones was also demonstrated.