Maternal Genetic Polymorphisms of Phase II Metabolic Enzymes and the Risk of Fetal Neural Tube Defects

Wang Linlin; Jin Lei; Liu Jufen; Zhang Yali; Yuan Yue; Yi Deqing; Ren Aiguo

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Maternal Genetic Polymorphisms of Phase II Metabolic Enzymes and the Risk of Fetal Neural Tube Defects

机译：II期代谢酶的母亲遗传多态性和胎儿神经管缺陷的风险。

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BackgroundMaternal exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with the risk of fetal neural tube defects (NTDs). Whether maternal genetic variants related to PAH metabolism contribute to the development of fetal NTDs remains unclear.

机译：背景母体暴露于多环芳烃（PAHs）与胎儿神经管缺损（NTDs）的风险有关。尚不清楚与PAH代谢相关的母亲遗传变异是否有助于胎儿NTD的发展。

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《Birth defects research, Part A. Clinical and molecular teratology》 |2014年第1期|共9页
作者
Wang Linlin; Jin Lei; Liu Jufen; Zhang Yali; Yuan Yue; Yi Deqing; Ren Aiguo;
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正文语种 eng
中图分类生物形态学;
关键词
indoor air pollution; neural tube defects; phase II metabolic enzymes; single nucleotide polymorphism; sulfotransferase;

机译：室内空气污染;神经管缺陷;II期代谢酶;单核苷酸多态性;磺基转移酶;

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1. Maternal Genetic Polymorphisms of Phase II Metabolic Enzymes and the Risk of Fetal Neural Tube Defects [J] . Wang Linlin, Jin Lei, Liu Jufen, Birth defects research, Part A. Clinical and molecular teratology . 2014,第1期

机译：II期代谢酶的母亲遗传多态性和胎儿神经管缺陷的风险。
2. Association between Maternal COMT Gene Polymorphisms and Fetal Neural Tube Defects Risk in a Chinese Population [J] . Liu Jufen, Wang Linlin, Fu Yunting, Birth defects research, Part A. Clinical and molecular teratology . 2014,第1期

机译：孕妇COMT基因多态性与中国人口胎儿神经管缺陷风险之间的关联。
3. Association of neural tube defects with maternal alterations and genetic polymorphisms in one-carbon metabolic pathway [J] . Chun-Quan Cai, Yu-Lian Fang, Jian-Bo Shu, Italian journal of pediatrics . 2019,第1期

机译：一碳代谢途径中神经管缺陷与母亲改变和遗传多态性的关系
4. Associations between maternal complex environmental exposure and the risk of fetal neural tube defects in north China [C] . Wang B Joint annual meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology . 2019

机译：孕产妇复杂环境暴露与华北胎儿神经管畸形风险的关系
5. Maternal and newborn polymorphisms in phase I/II metabolic genes contribute to risk of adverse reproductive outcomes. [D] . Nukui, Tomoko. 2002

机译：I / II期代谢基因中的母体和新生儿多态性会导致不良生殖结果的风险。
6. A Polymorphism R653Q in the Trifunctional Enzyme Methylenetetrahydrofolate Dehydrogenase/Methenyltetrahydrofolate Cyclohydrolase/Formyltetrahydrofolate Synthetase Is a Maternal Genetic Risk Factor for Neural Tube Defects: Report of the Birth Defects Research Group [O] . Lawrence C. Brody, Mary Conley, Christopher Cox, 2002

机译：三功能酶亚甲基四氢叶酸脱氢酶/亚甲基四氢叶酸环化酶/甲酰四氢叶酸合成酶中的多态性R653Q是神经管缺陷的母体遗传危险因素：出生缺陷研究小组的报告
7. A Polymorphism, R653Q, in the Trifunctional Enzyme Methylenetetrahydrofolate Dehydrogenase/Methenyltetrahydrofolate Cyclohydrolase/Formyltetrahydrofolate Synthetase Is a Maternal Genetic Risk Factor for Neural Tube Defects: Report of the Birth Defects Research Group [O] . Brody, Lawrence C., Conley, Mary, Cox, Christopher, 2002

机译：三功能酶亚甲基四氢叶酸脱氢酶/亚甲基四氢叶酸环化酶/甲酰四氢叶酸合成酶中的多态性R653Q是神经管缺陷的母体遗传危险因素：出生缺陷研究小组的报告
8. Impact of Risk Factors and Genetic Polymorphism in Metabolic Enzymes on Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers and Non-Mutation Carriers [R] . Eyfjord, J. E. 2000

机译：代谢酶中的危险因素和遗传多态性对BRCa1和BRCa2突变携带者和非突变携带者乳腺癌风险的影响

Maternal Genetic Polymorphisms of Phase II Metabolic Enzymes and the Risk of Fetal Neural Tube Defects

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