Effect of Intralipid (R) on the Dose of Ropivacaine or Levobupivacaine Tolerated by Volunteers A Clinical and Pharmacokinetic Study

摘要

Background: Rapid intravenous administration of lipid emulsion has become the standard treatment of severe local anesthetic systemic toxicity. This experiment in volunteers aimed at determining the effect of Intralipid (R) administration on the time to neurologic symptoms.