IN the summer of 2002, the reality television hit American Idol swept the world and instantly became a trend-setting phenomenon. In similar award-winning fashion, this issue of Anesthesiology features a study by Fox (no relationship with the television network) et at. that was orally presented at the 2008 American Society of Anesthesiologists Annual Meeting session "Best Abstracts of the Meeting: Anesthesiology Editor's Picks." The authors associated candidate gene variation in the natriuretic peptide system with cardiovascular phenotype, namely ventricular dysfunction (VnD) after coronary artery bypass grafting (CABG). The magnitude of this modern collaborative clinical trial is remarkable. These authors have previously written an excellent pharma-cogenetics review in Anesthesiology,2 but the present study epitomizes the expanding emphasis on clinical genomics, a formative subject field in the anesthesiology literature.
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