Multiprofile immunochemical indication of the causative agents in infectious diseases

摘要

A variant of multiprofile immunochemical indication of the causative agents of infectious diseases is described on the basis of a protein microarray with a low-density antibody population. The method is a multiplex variant of dot ELISA whose sensitivity increased due to the use of a colloid gold-based conjugate and an efficient system of its development. The method shows both its multiprofile character with its easiness-to-prepare and to use protein microchips. Having the similar sensitivity, it has obvious advantages over the routine ELISA in the rate of obtaining results, the consumption of reagents, labor intensiveness, and specific cost.