beta-CYCLODEXTRIN INCLUSION COMPLEX OF CURCUMIN

摘要

Formation of inclusion complex of curcumin with p-cydodextrin (beta-CD) has been characterized by absorption and fluorescence spectroscopy. From temperature-dependent fluorescence measurements, the thermodynamic parameters AH and AS, for the complexation were estimated. Kinetics of binding was studied by stopped flow technique, from which the binding constants for inclusion complex was estimated. Further, influence of such inclusion complex on change in superoxide radical scavenging property of curcumin was examined using xanthine/xanthine oxidase assay.