Interference of haemolysis and hyperproteinemia on Sodium, Potassium, and Chloride measurements in canine serum samples

摘要

The exact measurement of Sodium (Na+), Potassium (K+), and Chloride (Cl?) ion concentrations in serum samples is important for correct diagnosis and therapy, and a knowledge of the interference factors which influence the analytic method used, ensures correct reading of laboratory data (Di Bartola et al. 1999). Serum haemolysis may cause pseudohyperkaliemia in humans (Miseta et al. 1992), in some breeds of dog (Akitas) having high K+ concentration in erythrocytes (Green 1996), and in new-born puppies (Berry et al. 1991); furthermore it may cause pseudohypochloremia by haematic dilution.