Microangiopathic hemolytic anemia in pregnancy

摘要

Microangipathic hemolytic anemia (MAHA) is a serious diagnosis and difficult to manage in pregnant patients as multiple life threatening conditions could present with MAHA. ADAMTSI3 enzyme activity can be affected during pregnancy with multiple factors. A persistent extremely low ADAMTSI3 enzyme activity levels, without an inhibitor, after the delivery was an important factor to establish the diagnosis. We present a case of likely congenital ADAMSTI3 deficiency that manifested for the first time in a pregnant woman at week 37 of pregnancy.(C) 2017 Elsevier Ltd. All rights reserved.