Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users

Setnik Beatrice; Bass Almasa; Bramson Candace; Levy-Cooperman Naama; Malhotra Bimal; Matschke Kyle; Geoffroy Pierre; Sommerville Kenneth W.; Wolfram Gernot

首页> 外文期刊>Pain medicine : >Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users

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Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users

机译：滥用ALO-02的潜在研究（围绕螯盐释放的纳曲酮）与口服施用的立即释放羟考酮与非依赖性娱乐阿片类药物

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Objective. To evaluate the abuse potential of ALO-02, an abuse-deterrent formulation comprising pellets of extended-release oxycodone hydrochloride surrounding sequestered naltrexone hydrochloride.

机译：客观的。为了评估AlO-02的滥用潜力，一种滥用抑制制剂，包括盐酸纳氏萘酮盐酸盐的延长释放羟酮的颗粒。

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来源
《Pain medicine :》 |2017年第6期|共12页
作者
Setnik Beatrice; Bass Almasa; Bramson Candace; Levy-Cooperman Naama; Malhotra Bimal; Matschke Kyle; Geoffroy Pierre; Sommerville Kenneth W.; Wolfram Gernot;
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作者单位

Pfizer Inc Global Innovat Pharma Neurosci &

Pain Global Prod Dev Durham NC USA;

Pfizer Inc Global Innovat Pharma Clin Sci Global Prod Dev Durham NC USA;

Pfizer Inc Global Innovat Pharma Clin Sci Global Prod Dev Groton CT 06340 USA;

INC Res LLC Early Phase Toronto ON Canada;

Pfizer Inc Global Innovat Pharma Clin Pharmacol Global Prod Dev New York NY USA;

Pfizer Inc Global Prod Dev Global Innovat Pharma Stat Collegeville PA USA;

INC Res LLC Early Phase Toronto ON Canada;

Pfizer Inc Global Innovat Pharma Neurosci &

Pain Global Prod Dev Durham NC USA;

Pfizer Inc Global Innovat Pharma Neurosci &

Pain Global Prod Dev Durham NC USA;

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原文格式 PDF
正文语种 eng
中图分类症状诊断学;
关键词
Opioids; Abuse Potential; ALO-02; Abuse Deterrent; Oxycodone;

机译：阿片类药物;滥用潜力;ALO-02;滥用威慑;羟考酮;

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专利

1. Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users [J] . Setnik Beatrice, Bass Almasa, Bramson Candace, Journal of Turbulence . 2017,第6期

机译：滥用ALO-02的潜在研究（围绕螯盐释放的纳曲酮）与口服施用的立即释放羟考酮与非依赖性娱乐阿片类药物
2. Intranasal Administration of Crushed ALO-02 (Extended-Release Oxycodone With Sequestered Naltrexone): A Randomized, Controlled Abuse-Potential Study in Nondependent Recreational Opioid Users [J] . The Journal of Clinical Pharmacology: Official Journal of the American College of Clinical Pharmacology . 2015,第12期

机译：粉碎的ALO-02（隔离型纳曲酮的扩展释放羟考酮）的鼻内给药：非依赖性休闲类鸦片使用者的随机，受控滥用潜能研究
3. Randomized, double-blind, placebo-controlled and active-controlled study to assess the relative abuse potential of oxycodone HCl-niacin tablets compared with oxycodone alone in nondependent, recreational opioid users [J] . Lynn R Webster, Robert L Rolleri, Glenn C Pixton, Substance Abuse and Rehabilitation . 2012,第1期

机译：随机，双盲，安慰剂对照和主动对照研究评估非依赖性休闲阿片类药物中羟考酮HCl烟酸片与单独使用羟考酮的相对滥用潜力
4. Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users [O] . Beatrice Setnik, Almasa Bass, Candace Bramson, -1

机译：与非依赖性休闲阿片类药物口服给药的ALO-02（延长释放的羟考酮包围隔离纳曲酮）与立即释放羟考酮的滥用潜能研究
5. Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users [O] . Beatrice Setnik, Almasa Bass, Candace Bramson, 2016

机译：滥用ALO-02的潜在研究（围绕释放纳曲酮的延长释放氧化萘酮）与立即释放的羟考酮在口服释放到非依赖性娱乐阿片类药物

Abuse Potential Study of ALO-02 (Extended-Release Oxycodone Surrounding Sequestered Naltrexone) Compared with Immediate-Release Oxycodone Administered Orally to Nondependent Recreational Opioid Users

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