Prognostic Significance of Total Lymphocyte Count, Neutrophil-to-lymphocyte Ratio, and Platelet-to-lymphocyte Ratio in Limited-stage Small-cell Lung Cancer

摘要

We sought markers of survival and disease control among patients treated for limited-stage small-cell lung cancer. High pretreatment total lymphocyte count was linked with superior (and high neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios with inferior) median and 2-year overall survival, findings confirmed in multivariate Cox regression. Baseline lymphopenia was an indicator of poor prognosis in patients with limited-stage small-cell lung cancer.