Significance of EGFR signaling pathway genetic alterations in radically resected non-small cell lung cancers from a Polish cohort. One institutional study

Kowalczuk Oksana; Kozlowski Miroslaw; Milewski Robert; Minarowski Lukasz; Reszec Joanna

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Significance of EGFR signaling pathway genetic alterations in radically resected non-small cell lung cancers from a Polish cohort. One institutional study

机译：EGFR信号通路基因改变在波兰人群的根治性切除非小细胞肺癌中的意义。一项机构研究

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Purpose: We evaluated the distribution and clinical impact of EGFR, KRAS and HER2 copy number gains and EGFR, KRAS and BRAF activating mutations in resected non-small cell lung cancers (NSCLCs) from 151 Polish patients.

机译：目的：我们评估了151名波兰患者切除的非小细胞肺癌（NSCLC）中EGFR，KRAS和HER2拷贝数增加以及EGFR，KRAS和BRAF激活突变的分布及其临床影响。

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来源
《Advances in medical sciences.》 |2015年第2期|共10页
作者
Kowalczuk Oksana; Kozlowski Miroslaw; Milewski Robert; Minarowski Lukasz; Reszec Joanna;
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正文语种 eng
中图分类医药、卫生;
关键词
NSCLC; Gene copy gain; EGFR mutations; KRAS mutations;

机译：NSCLC;基因拷贝获得;EGFR突变;KRAS突变;

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1. Significance of EGFR signaling pathway genetic alterations in radically resected non-small cell lung cancers from a Polish cohort. One institutional study [J] . Kowalczuk Oksana, Kozlowski Miroslaw, Milewski Robert, Advances in medical sciences. . 2015,第1a2期

机译：EGFR信号通路基因改变在波兰人群的根治性切除非小细胞肺癌中的意义。一项机构研究
2. Exploring microRNA-mediated alteration of EGFR signaling pathway in non-small cell lung cancer using an mRNA:miRNA regression model supported by target prediction databases [J] . Wang Fengfeng, Chan Lawrence W. C., Law Helen K. W., Genomics . 2014,第6PB期

机译：使用靶标预测数据库支持的mRNA：miRNA回归模型探索非小细胞肺癌中microRNA介导的EGFR信号通路改变
3. Significance of targeted therapy and genetic alterations in EGFR, ALK, or KRAS on survival in patients with non-small cell lung cancer treated with radiotherapy for brain metastases [J] . Kimberley S. Mak, Justin F. Gainor, Andrzej Niemierko, Neuro-Oncology . 2015,第2期

机译：EGFR，ALK或KRAS靶向治疗和基因改变对非小细胞肺癌脑转移放疗患者生存的意义
4. Mass spectrometry-based quantitative analysis for decoding site-specific alteration of Sialo-glycoproteome in EGFR-subtype of non-small cell lung cancers [C] . Yi-Ju Chen, Yu-Hsien Lin, Kay-Hooi Khoo, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：基于质谱的基于质谱的非小细胞肺癌中唾液酸糖组种位点特异性改变的定量分析
5. Effects of TNFAIP8 knockdown on EGFR and IGF-1R signaling and cytotoxicities of targeted drugs in non-small cell lung cancer cells [D] . Day, Timothy Francis 2015

机译：TNFAIP8组合对非小细胞肺癌细胞EGFR和IGF-1R信号传导及靶向药物的细胞毒性的影响
6. EGFR mutation testing on cytological and histological samples in non-small cell lung cancer: a Polish single institution study and systematic review of European incidence [O] . Anna Szumera-Ciećkiewicz, Włodzimierz T Olszewski, Andrzej Tysarowski, 2013

机译：非小细胞肺癌细胞学和组织学样本的EGFR突变测试：波兰单一机构研究和欧洲发病率的系统综述
7. Exploring microRNA-mediated alteration of EGFR signaling pathway in non-small cell lung cancer using an mRNA:miRNA regression model supported by target prediction databases [O] . Wang, F, Chan, LWC, Law, HKW, 2014

机译：使用靶标预测数据库支持的mRNA：miRNA回归模型探索非小细胞肺癌中microRNA介导的EGFR信号通路改变

Significance of EGFR signaling pathway genetic alterations in radically resected non-small cell lung cancers from a Polish cohort. One institutional study

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