Lethal 5-fluorouracil toxicity in a colorectal patient with severe dihydropyrimidine dehydrogenase (DPD) deficiency

Dhelens Carole; Bonadona Agnes; Thomas Fabienne; Chapuis Claire; Potton Leila; Marsili Sabrina; Bedouch Pierrick; Schwebel Carole

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Lethal 5-fluorouracil toxicity in a colorectal patient with severe dihydropyrimidine dehydrogenase (DPD) deficiency

机译：致致死的5-氟尿嘧啶毒性在具有严重二氢嘧啶脱氢酶（DPD）缺乏的结肠直肠患者中

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来源
《International journal of colorectal disease.》 |2016年第3期|共3页
作者
Dhelens Carole; Bonadona Agnes; Thomas Fabienne; Chapuis Claire; Potton Leila; Marsili Sabrina; Bedouch Pierrick; Schwebel Carole;
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作者单位

Univ Grenoble Ctr Hosp Dept Pharm Grenoble France;

Univ Grenoble Ctr Hosp Dept Med Intens Care Unit Grenoble France;

Inst Claudius Regaud IUCT O Dept Pharmacol Toulouse France;

Univ Grenoble Ctr Hosp Dept Pharm Grenoble France;

Univ Grenoble Ctr Hosp Dept Med Intens Care Unit Grenoble France;

Inst Claudius Regaud IUCT O Dept Pharmacol Toulouse France;

Univ Grenoble Ctr Hosp Dept Pharm Grenoble France;

Univ Grenoble Ctr Hosp Dept Med Intens Care Unit Grenoble France;

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原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
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1. Lethal 5-fluorouracil toxicity in a colorectal patient with severe dihydropyrimidine dehydrogenase (DPD) deficiency [J] . Dhelens Carole, Bonadona Agnes, Thomas Fabienne, International journal of colorectal disease. . 2016,第3期

机译：严重二氢嘧啶脱氢酶（DPD）缺乏的大肠癌患者的5-氟尿嘧啶致命毒性
2. Benefit of uridine triacetate (Vistogard) in rescuing severe 5-fluorouracil toxicity in patients with dihydropyrimidine dehydrogenase (DPYD) deficiency [J] . Saif Muhammad Wasif, Diasio Robert B. Cancer chemotherapy and pharmacology. . 2016,第1期

机译：三乙酸尿苷（Vistogard）在挽救二氢嘧啶脱氢酶（DPYD）缺乏症患者中严重的5-氟尿嘧啶毒性中的作用
3. 661 POSTER The effect of dihydropyrimidine dehydrogenase (DPD) activity and germline thymidylate synthase (TS) gene polymorphisms on the survival of colorectal cancer patients treated by adjuvant 5-fluorouracil [J] . European Journal of Cancer Supplements . 2005,第2期

机译：661 POSTER二氢嘧啶脱氢酶（DPD）活性和种系胸苷酸合酶（TS）基因多态性对5-氟尿嘧啶辅助治疗大肠癌患者生存的影响
4. Thymidine Phosphorylase (TP) and Dihydropyrimidine Dehydrogenase (DPD) in Colorectal Cancer: Gene Expressions Level vs. Protein Level [C] . J. Sobajima, T. Gonda, T. Oosawa, International Society of University Colon and Rectal Surgeons . 2006

机译：结直肠癌中胸苷磷酸化酶（TP）和二氢嘧啶脱氢酶（DPD）：基因表达水平与蛋白质水平
5. Development, validation, and use of a novel [2-carbon-13] uracil breath test to detect dihydropyrimidine dehydrogenase deficiency. [D] . Mattison, Lori K. 2006

机译：开发，验证和新型的[2-carbon-13]尿嘧啶呼气试验来检测二氢嘧啶脱氢酶缺乏症。
6. Dihydropyrimidine dehydrogenase deficiency in patients with severe toxicity after 5-fluorouracil: a retrospective single-center study [O] . Stephanie Detailleur, Eva Segelov, Marzia Del Re, 2021

机译：5-氟尿嘧啶后严重毒性患者的二氢嘧啶脱氢酶缺乏：回顾性单中心研究
7. High-resolution melting analysis of the common c.1905+1G>A mutation causing dihydropyrimidine dehydrogenase deficiency and lethal 5-fluorouracil toxicity [O] . Emma eBorràs, Emma eDotor, Àngels eArcusa, 2013

机译：常见c.1905 + 1G> a突变的高分辨率熔解分析引起二氢嘧啶脱氢酶缺乏和致死的5-氟尿嘧啶毒性

Lethal 5-fluorouracil toxicity in a colorectal patient with severe dihydropyrimidine dehydrogenase (DPD) deficiency

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