ADVANCES ON BIOLOGICAL MARKERS IN EARLY DIAGNOSIS OF ALZHEIMER DISEASE

摘要

Alzheimer disease (AD) represents the most common neurodegenerative disease worldwide, accounting for 60% -70% of cases of progressive cognitive impairment in elderly patients. The prevalence of dementia of the Alzheimer type (DAT) doubles every 5 years after the age of 60 years, increasing from a prevalence of 1% among those 60-64 years old up to 40% of those aged 85 years and older [1,2].