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首页> 外文期刊>BJOG: an international journal of obstetrics and gynaecology >Metabolic acidosis at birth and suboptimal care--illustration of the gap between knowledge and clinical practice.
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Metabolic acidosis at birth and suboptimal care--illustration of the gap between knowledge and clinical practice.

机译:出生时的代谢性酸中毒和治疗效果欠佳-说明知识与临床实践之间的差距。

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OBJECTIVE: To evaluate the occurrence and nature of suboptimal intrapartum care in cases with metabolic acidosis in the newborn, and to estimate the degree to which this may be prevented. DESIGN: Case-control study. Clinical audit. Setting Delivery units at two university hospitals in Sweden. POPULATION: Out of 28 486 deliveries, 161 neonates > or =34 weeks of gestational age were born with metabolic acidosis. METHODS: Cases (n = 161): umbilical artery pH < 7.05 and base deficit > or =12 mmol/l. Controls (n = 322): pH > or = 7.05 and Apgar score > or =7 at 5 minutes. Obstetric characteristics and oxytocin administration were recorded. The last 2 hours of electronic fetal monitoring before delivery were evaluated blinded to outcome. Intrapartum management was analysed for suboptimal care by using predefined criteria. MAIN OUTCOME MEASURE: Suboptimal intrapartum care. RESULTS: Case and control comparisons displayed an occurrence of suboptimal care in 49.1% versus 13.0% (P < 0.001), oxytocin misuse in 46.6% versus 13.0% (P < 0.001), a failure to respond to a pathological cardiotocographic pattern in 19.9% versus 1.2% (P < 0.001) and suboptimal care related to vacuum deliveries in 3.1% versus 0.3% (P < 0.01) respectively. CONCLUSION: Metabolic acidosis at birth is often associated with suboptimal intrapartum care. The high rate of suboptimal care with regard to oxytocin use and fetal surveillance illustrate a gap between guidelines and clinical practice. Metabolic acidosis and related neonatal morbidity could potentially be prevented in 40-50% of cases. The adherence to guidelines must be checked.
机译:目的:评估新生儿代谢性酸中毒的最佳分娩期护理的发生和性质,并估计可以预防的程度。设计:病例对照研究。临床审核。在瑞典的两家大学医院设置分娩单位。人口:在28 486例分娩中,有161例胎龄≥34周的新生儿患有代谢性酸中毒。方法:病例(n = 161):脐动脉pH <7.05,碱基缺乏度>或= 12 mmol / l。对照(n = 322):5分钟时pH≥7.05且Apgar评分≥7。记录产科特征和催产素给药。分娩前的最后两个小时电子胎儿监测被评估为对结果不知情。通过使用预定义的标准,对分娩期管理进行了次优护理分析。主要观察指标:分娩期护理效果欠佳。结果:病例和对照比较显示,次优护理发生率分别为49.1%和13.0%(P <0.001),催产素滥用率分别为46.6%和13.0%(P <0.001),对病理心动图无反应的率为19.9%与1.2%(P <0.001)相比,次优护理与真空分娩相关的比例分别为3.1%和0.3%(P <0.01)。结论:出生时代谢性酸中毒通常与分娩期护理效果欠佳有关。催产素使用和胎儿监护方面的次优护理率很高,这说明指南与临床实践之间存在差距。可以在40-50%的病例中预防代谢性酸中毒和相关的新生儿发病率。必须检查是否遵守准则。

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