DEVELOPMENT OF A NOVEL FULL BODY PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO SIMULATE COMPLEX PARENT-METABOLITE KINETICS USING METHAMPHETAMINE-AMPHETAMINE AS MODEL COMPOUNDS.

Huang W.; Czuba L.; Isoherranen N.

首页> 外文期刊>Clinical Pharmacology and Therapeutics >DEVELOPMENT OF A NOVEL FULL BODY PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO SIMULATE COMPLEX PARENT-METABOLITE KINETICS USING METHAMPHETAMINE-AMPHETAMINE AS MODEL COMPOUNDS.

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DEVELOPMENT OF A NOVEL FULL BODY PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO SIMULATE COMPLEX PARENT-METABOLITE KINETICS USING METHAMPHETAMINE-AMPHETAMINE AS MODEL COMPOUNDS.

机译：用甲基苯丙胺-Amphetamine作为模型化合物模拟复合亲子 - 代谢动力学的新型全身基于体生理学药代动力学模型。

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来源
《Clinical Pharmacology and Therapeutics》 |2019年第1期|共1页
作者
Huang W.; Czuba L.; Isoherranen N.;
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作者单位

Univ Washington Seattle WA 98195 USA;

Univ Washington Seattle WA 98195 USA;

Univ Washington Seattle WA 98195 USA;

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原文格式 PDF
正文语种 eng
中图分类药理学;
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1. DEVELOPMENT OF A NOVEL FULL BODY PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO SIMULATE COMPLEX PARENT-METABOLITE KINETICS USING METHAMPHETAMINE-AMPHETAMINE AS MODEL COMPOUNDS. [J] . Huang W., Czuba L., Isoherranen N. Clinical Pharmacology and Therapeutics . 2019,第Suppla1期

机译：用甲基苯丙胺-Amphetamine作为模型化合物模拟复合亲子 - 代谢动力学的新型全身基于体生理学药代动力学模型。
2. Physiologically-based modeling of monoclonal antibody pharmacokinetics in drug discovery and development [J] . Patrick M. Glassman, Joseph P. Balthasar Drug metabolism and pharmacokinetics. . 2019,第1期

机译：基于生理学的药物研发中单克隆抗体药代动力学建模
3. Poster #050: Simulating Altered Omeprazole Kinetics in Elderly Individuals Using Physiologically-based Pharmacokinetic Population Modeling [J] . Jan-Frederik Schlender, Niels Lautenbach, Tobias Kanacher, Clinical pharmacology in drug development . 2016,第Suppla1期

机译：海报＃050：使用基于生理学的药代动力学人口模拟模拟老年人的奥美拉唑动力学改变
4. A multi-compartmental model generally applicable to physiologically-based pharmacokinetics [C] . Dr. Philip A. Arundel IFAC symposium on modelling and control in biomedical systems . 1997

机译：通常适用于基于生理的药代动力学的多室模型
5. Physiologically-based pharmacokinetic modeling of simple and complex mixtures of gasoline and the gasoline components N-hexane, benzene, toluene, ethylbenzene, and xylene. [D] . Dennison, James E., Jr. 2004

机译：汽油和汽油成分N-己烷，苯，甲苯，乙苯和二甲苯的简单和复杂混合物的基于生理的药代动力学模型。
6. Effects of the FcRn developmental pharmacology on the pharmacokinetics of therapeutic monoclonal IgG antibody in pediatric subjects using minimal physiologically-based pharmacokinetic modelling [O] . Deni Hardiansyah, Chee Meng Ng 2018

机译：FcRn发育药理学对基于最小生理学的药代动力学模型对治疗性单克隆IgG抗体在儿科患者体内药代动力学的影响
7. Effects of the FcRn developmental pharmacology on the pharmacokinetics of therapeutic monoclonal IgG antibody in pediatric subjects using minimal physiologically-based pharmacokinetic modelling [O] . Deni Hardiansyah, Chee Meng Ng 2018

机译：FCRN发育药理学对使用最小生理学药代动力学建模的儿科对象治疗单克隆IgG抗体的药代动力学
8. Quantitative Evaluation of Dichloroacetic Acid Kinetics in Human -- A Physiologically-Based Pharmacokinetic Modeling Investigation [R] . Li, T., Schultz, I., Keys, D. A., 2008

机译：人体内二氯乙酸动力学的定量评价 - 基于生理学的药代动力学模型研究

DEVELOPMENT OF A NOVEL FULL BODY PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL TO SIMULATE COMPLEX PARENT-METABOLITE KINETICS USING METHAMPHETAMINE-AMPHETAMINE AS MODEL COMPOUNDS.

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