Retinal haemorrhage, subretinal pigment epithelial deposits and serous macular detachment in light chain deposition disease

摘要

Light chain deposition disease (LCDD) is a rare form of monoclonal gammopathy, characterised by deposits of either kappa or gamma light chains (LC) most frequendy in the kidney, causing renal failure.1 LCDD is diagnosed by immunohistochemistry and transmission electron microscopy of renal biopsies.2 The frequency of ocular disease is not known (personal communication, National Amyloidosis Centre, University College London).