The Affordable Medicines Facility-malaria: killing it slowly

摘要

In 2002, we served on a committee for the Institute of Medicine of the US National Academy of Sciences that was asked to recommend measures for getting new and effective, but relatively expensive, artemisinin-based antimalarials to poor populations.1 People were still buying chloroquine because it was cheap-and available, but it was becoming less effective because of parasite resistance, and malaria mortality was increasing.2 At that time, artemisinin derivatives were highly effective but no other drugs in the pipeline were expected to be as good.