Authors' reply

摘要

We appreciate the concerns expressed by Athanasios Chalkias and Theodoras Xanthos about the role of increased intra-abdominal pressure in the patho-genesis of acute kidney injury (AKI), and indeed mention this possibility in our Seminar.1 However, as shown in a prospective investigation,2 although increased intra-abdominal pressure is common in patients in intensive care, its clinical meaning and renal consequences remain unclear in the absence of a full abdominal compartment syndrome. Therefore, we argue that routine measurement of intra-abdominal pressure is not justified unless intra-abdominal compartment syndrome seems clinically likely and renal function is being rapidly lost.