to the editor: The review by Singer and Talan (March 13 issue)1 describes the management of skin abscesses in the era of methicillin-resistant Staphylococcus aureus (MRSA).1 In a 3-year study of soft-tissue and invasive infections caused by Pan-ton-Valentine leukocidin (PVL)-positive methi-cillin-susceptible S. aureus (PVL-MSSA) and MRSA in a pediatric hospital, we found that PVL is largely diffused in both community-associated MRSA (CA-MRSA) and in MSSA,2-3 as has been described,4 and MRSA genotypes have a particular distribution in different geographic regions.5 In our experience, PVL-MSSA strains were more frequent than PVL-MRSA, with all the latter belonging to already described clones such as USA300, Pediatric, and South West Pacific.
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