An Unprecedented Tandem Annulation of omega-Azido-1-alkynes with Diaryliodonium Salts: A Facile Synthesis of Polycyclic Quinolines

摘要

Polysubstituted quinolines are synthesized through an unprecedented cascade annulation of -azido-1-alkynes with diaryliodonium salts, which serve as C2-building blocks. The reaction proceeds smoothly and is catalyzed by Cu(I) catalysts to give various quinolines in good isolated yields with simple operation under mild conditions.