Ruthenium-Catalyzed Alkenylation of Arenes with Alkynes or Alkenes by 1,2,3-Triazole-Directed C-H Activation

摘要

The ruthenium-catalyzed alkenylation of arenes with alkynes or alkenes has been achieved by using 1,2,3-triazole as the directing group for the C-H activation. With [Ru(p-cymene)Cl-2](2) as the catalyst and Cu(OAc)(2)H2O and AgSbF6 as additives, various triazole-substituted arenes reacted readily with a range of internal alkynes or terminal alkenes to afford di- or monoalkenylated arenes with high regioselectivity and in moderate-to-excellent yields.