Antibiotics vs Appendectomy for Uncomplicated Acute Appendicitis

摘要

The term evidence-based medicine was first coined by Sack-ett and colleagues1 as "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients." The key to practicing evidence-based medicine is applying the best current knowledge to decisions in individual patients. Medical knowledge is continually and rapidly expanding, and it is impossible for an individual clinician to read all the medical literature. For clinicians to practice evidence-based medicine, they must have the skills to read and interpret the medical literature so that they can determine the validity, reliability, credibility, and utility of individual articles. These skills are known as critical appraisal skills. Generally, critical appraisal requires that the clinician have some knowledge of biostatistics, clinical epidemiology, decision analysis, and economics as well as clinical knowledge.