Fetal methotrexate/aminopterin syndrome in an adult: a likely case with ectodermal abnormalities.

摘要

Exposure to folic acid antagonists during the first trimester of pregnancy may lead to fetal death or to a recognized pattern of malformations in liveborn infants. Few reports of affected adult individuals have been observed. In this report, the clinical findings of a likely affected 45-year-old woman are described and compared with reported cases. New ectodermal abnormalities are also described.