Role of the GALAD and BALAD-2 Serologic Models in Diagnosis of Hepatocellular Carcinoma and Prediction of Survival in Patients

摘要

BACKGROUND & AIMS: GALAD and BALAD-2 are statistical models for estimating the likelihood of the presence of hepatocellular carcinoma (HCC) in individual patients with chronic liver disease and the survival of patients with HCC, respectively. Both models use objective measures, particularly the serum markers a-fetoprotein (AFP), AFP-L3, and des-gamma-carboxyprothrombin. We aimed to validate these models in an international cohort of patients with HCC and assess their clinical performance.