First Synthesis of Bis(di(indolyl)aryl)methanes From Bis(salicylaldehydes)

Bakthadoss Manickam; Devaraj Anthonisamy; Srinivasan Jayakumar

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First Synthesis of Bis(di(indolyl)aryl)methanes From Bis(salicylaldehydes)

机译：由双（水杨醛）合成双（二（吲哚基）芳基）甲烷

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In this article, a simple method for the synthesis of bis(di(indolyl)aryl)methanes is described. The iodine-catalyzed (5mol%) reaction of indoles with various bis(salicylaldehyde) derivatives affords the bis(di(indolyl)aryl)methanes in excellent yields. The reaction works well under mild reaction condition with shorter reaction time.

机译：在本文中，描述了一种简单的合成双（二（吲哚基）芳基）甲烷的方法。吲哚与各种双（水杨醛）衍生物的碘催化的（5mol％）反应以优异的产率提供了双（二（吲哚基）芳基）甲烷。在温和的反应条件下，反应时间短，反应良好。

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《Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry》 |2015年第2期|共7页
作者
Bakthadoss Manickam; Devaraj Anthonisamy; Srinivasan Jayakumar;
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正文语种 eng
中图分类有机化学;
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1. First Synthesis of Bis(di(indolyl)aryl)methanes From Bis(salicylaldehydes) [J] . Bakthadoss Manickam, Devaraj Anthonisamy, Srinivasan Jayakumar Journal of Heterocyclic Chemistry: The International Journal of Heterocyclic Chemistry . 2015,第2期

机译：由双（水杨醛）合成双（二（吲哚基）芳基）甲烷
2. Poly(N,N'-dichloro-N-ethyl-benzene-1, 3-disulfonamide) and N,N,N',N'-Tetrachlorobenzene-1,3-disulfonamide as Novel Catalytic Reagents for Synthesisof Bis-indolyl, Tris-indolyl, Di(bis-indolyl), Tri(bis-indolyl) and Tetra(bis-indolyl)Methanes under Solid-State, Solvent and Water Conditions [J] . Ramin Ghorbani-Vaghei, Hojat Veisi Journal of the Brazilian Chemical Society . 2010,第2期

机译：聚（N，N'-二氯-N-乙基苯-1,3-二磺酰胺）和N，N，N'，N'-四氯苯-1,3-二磺酰胺作为合成双吲哚基，Tris的新型催化试剂固态，溶剂和水条件下的-吲哚基，二（双-吲哚基），三（双-吲哚基）和四（双-吲哚基）甲烷
3. Synthesis of aryl/alkyl(2,2-bis-3-methylindolyl)methanes and aryl(3,3-bis indolyl)methanes promoted by secondary amine based ionic liquids and microwave irradiation [J] . Pranab J. Das, Jupitara Das Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2012,第35期

机译：仲胺基离子液体和微波辐射促进的芳基/烷基（2,2-双-3-甲基吲哚基）甲烷和芳基（3,3-双吲哚基）甲烷的合成
4. Ultrasound-assisted green synthesis of bis(indolyl)methanes catalyzed by acidic Ionic liquid (CH2)4SO4HMIMHSO4 [C] . Yingming Mo, Hongjun Zang, Bowen Cheng 2010 International Conference on Mechanic Automation and Control Engineering . 2010

机译：酸性离子液体（CH 2 ） 4 SO 4 HMIM HSO <的超声辅助绿色合成双（吲哚基）甲烷inf> 4
5. Cytotoxicity of indole-ring substituted 1,1-bis (3'-indolyl)-1-(p-phenyl-t-butyl) methanes in colon cancer cells [D] . Newman, Kristin Laine. 2008

机译：吲哚环取代的1,1-双（3'-吲哚基）-1-（对苯基叔丁基）甲烷在结肠癌细胞中的细胞毒性
6. Development of an imidazole salt catalytic system for the preparation of bis(indolyl)methanes and bis(naphthyl)methane [O] . Xu Wang, Courtney C. Aldrich 2012

机译：开发用于制备双（吲哚基）甲烷和双（萘基）甲烷的咪唑盐催化系统
7. Poly(N,N'-dichloro-N-ethyl-benzene-1, 3-disulfonamide) and N,N,N',N'-tetrachlorobenzene-1,3-disulfonamide as novel catalytic reagents for synthesis of bis-indolyl, tris-indolyl, di(bis-indolyl), tri(bis-indolyl) and tetra(bis-indolyl)methanes under solid-state, solvent and water conditions [O] . Ramin Ghorbani-Vaghei, Hojat Veisi 2010

机译：聚（N，N'-二氯-N-乙基 - 苯-1,3-二硫磺酰胺）和N，N，N'，N'-四氯苯-1,3-二磺酰胺作为新型催化试剂，用于合成双吲哚（BIS-Indolyl），在固态，溶剂和水条件下，Tris-Indolyl，DI（双吲哚基），三（双吲哚基）和四（双吲哚基）甲烷

First Synthesis of Bis(di(indolyl)aryl)methanes From Bis(salicylaldehydes)

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