Behavior of 2-iminothiazolidin-4-one with different reagents

摘要

Annulations of 2-imino-4-thiazolidinone (5) via cycloaddition followed by cyclocondensation reaction with 1,3-diphenylpropenone (6), benzylidenemalonate, and 1,2-bis(chloromethyl)benzene gave 7, 19 and 20, respectively. Reaction of 5 with suitable electrophiles (Mannich bases of arylalkanone), 1,4-dichlorobenzene (diarylmethylation), and formylation afforded 8/9, 21/22, and 23, respectively.