Synthesis and Biological Activity of Novel 1,3,5-Trisubstituted 1,2,4-Triazole Derivatives

摘要

Triazole skeleton is ubiquitous in pharmaceutically important compounds. A novel series of indoline-containing triazole with different amides are described, which exhibit antibacterial and antifungal activities. The chemical synthesis strategies used, the complete characterization of the compounds, their in vitro screening, and the promising activity as reflected in the MIC values are reported.