A Novel Camphorsulfonyloxylactonization of Alkenoic Acids

摘要

The novel reaction of [hydroxyl (((+)-10-camphorsulfonyl)oxy)iodo]benzene (1) with alkenoic acids was reported. When 1 reacted with various 4-pentenoic acids in CH3CN, camphorsulfonylactons were obtained in excellent yields in short times, some had two diastereoisomers, whereas 1 reacted with 5- hexenoic acid, giving middle yield of camphorsulfonylacton; however, 3-butenoic and trans-3-hexenoic acids reacted with 1 slowly in CH2Cl2, only unsaturated lactones were provided.