Glycine-Catalyzed Easy and Efficient One-Pot Synthesis of Polyhydroquinolines Through Hantzsch Multicomponent Condensation under Controlled Microwave

摘要

Glycine, a novel heterogeneous organocatalyst, is found to be highly effective for the synthesis of polyhydroquinoline derivatives in a one-pot multicomponent reaction via Hantzsch condensation under controlled microwave (MW) irradiation. The combination of glycine and MW has promising features for the reaction response, such as the shortest reaction time, excellent product yields, and simple workup of the products.