An efficient and clean one-pot synthesis of 3,4-dihydropyrimidine-2(1H)-ones catalyzed by tungstate sulfuric acid in solvent-free conditions

摘要

Tungstate sulfuric acid catalyzes the three component condensation reaction of an aromatic aldehyde, urea and a beta-ketoester under solvent-free conditions to afford the corresponding dihydropyrimidinones in. high to excellent yields at room temperature.