Indole-5-phenylcarbamate derivatives as human non-pancreatic secretory phospholipase A2 inhibitor.

Liu Y; Han XF; Huang CK; Hao X; Lai LH

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Indole-5-phenylcarbamate derivatives as human non-pancreatic secretory phospholipase A2 inhibitor.

机译：吲哚-5-苯基氨基甲酸酯衍生物作为人非胰腺分泌磷脂酶A2抑制剂。

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摘要

The synthesis of the human non-pancreatic secretory phospholipase A2 inhibitor (IC(50)=1.81+/-0.59 microM) is reported.

机译：报告了人类非胰腺分泌磷脂酶A2抑制剂（IC（50）= 1.81 +/- 0.59 microM）的合成。

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《Bioorganic and Medicinal Chemistry Letters》 |2005年第20期|共3页
作者
Liu Y; Han XF; Huang CK; Hao X; Lai LH;
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正文语种 eng
中图分类基础医学;
关键词
Phenylcarbamates; Phospholipases A; 磷脂酶A类;

机译：Phenylcarbamates;Phospholipases A;磷脂酶A类;

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专利

1. Indole-5-phenylcarbamate derivatives as human non-pancreatic secretory phospholipase A2 inhibitor. [J] . Liu Y, Han XF, Huang CK, Bioorganic and Medicinal Chemistry Letters . 2005,第20期

机译：吲哚-5-苯基氨基甲酸酯衍生物作为人非胰腺分泌磷脂酶A2抑制剂。
2. Antibacterial properties of recombinant human non-pancreatic secretory phospholipase A2 [J] . QiuS., LaiL. Biochemical and Biophysical Research Communications . 2013,第2期

机译：重组人非胰分泌磷脂酶A2的抗菌特性
3. Reduction of circulating secretory phospholipase A2 levels by anti-tumor necrosis factor chimeric monoclonal antibody in patients with severe Crohn's disease. Relation between tumor necrosis factor and secretory phospholipase A2 in healthy humans and [J] . van-Dullemen HM, Wolbink GJ, Wever PC, Scandinavian journal of gastroenterology. . 1998,第10期

机译：重度克罗恩病患者中抗肿瘤坏死因子嵌合单克隆抗体可降低循环分泌性磷脂酶A2水平。正常人肿瘤坏死因子与分泌型磷脂酶A2的关系。
4. Secretory Phospholipase A2 as a Site Specific Trigger for Tumor Activationof a Novel Class of Liposomal Prodrug Lipids [C] . T. L. Andresen, S. S. Jensen, K. J?rgensen Controlled Release Society annual meeting . 2004

机译：分泌型磷脂酶A2作为新型脂质体前药脂质的肿瘤激活的位点特异性触发。
5. The Role of Secretory Phospholipase A2 Group IIA in Obesity and Metabolism [D] . Kuefner, Michael S. 2019

机译：分泌性磷脂酶A2 IIA组在肥胖和代谢中的作用
6. Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2 [O] . R.W. Schevitz, N.J. Bach, D.G. Carlson, -1

机译：人非胰腺分泌型磷脂酶A2的第一种有效和选择性抑制剂的基于结构的设计
7. Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2 [O] . R.W. Schevitz, N.J. Bach, D.G. Carlson, 1995

机译：基于结构的人非胰腺分泌磷脂酶A2的第一个有效和选择性抑制剂的设计

Indole-5-phenylcarbamate derivatives as human non-pancreatic secretory phospholipase A2 inhibitor.

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