Crohn Disease

摘要

n A 1932 issue of JAMA, Crohn, Ginzburg, and Op-penheimer1 brought into clear focus a new clinical entity with characteristic pathologic features that were previously only anecdotally recognized with uncertain meaning.2 This disease, originally called regional ileitis, has now assumed Crohn's name to recognize the bellwether nature of these published findings1 and to account for the now recognized protean manifestations of this clinical syndrome that may involve the entire gastrointestinal tract without restriction to the ileum as originally described