Medical Applications of Biotechnology

摘要

This theme issue of JAMA illustrates the promise and potential of biotechnology in medicine, with reports that demonstrate cutting-edge advances and novel discoveries in several rapidly evolving areas of medical research. In 2 studies on cancer detection, Casey and colleagues1 demonstrate that conversion analysis increases the diagnostic yield of germ-line mutations in colorectal cancer compared with conventional genomic sequencing, while Grossman and colleagues2 report that a proteomic assay may be a useful adjunct to cystoscopy for detecting bladder cancer.