Solubility advantage from amorphous etoricoxib solid dispersions

Dani Prateek; Puri Vibha; Bansal A. K.

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Solubility advantage from amorphous etoricoxib solid dispersions

机译：无定形依托昔布固体分散体的溶解度优势

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Objective: This study aimed to evaluate kinetic solubility advantage of amorphous etoricoxib solid dispersions prepared with three water soluble polymers and correlate it with solid state and supersaturated drug solution stabilization potential of these polymers.

机译：目的：本研究旨在评估由三种水溶性聚合物制备的非晶态依托昔布固体分散体的动力学溶解度优势，并将其与这些聚合物的固态和过饱和药物溶液稳定化潜力相关联。

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《Drug development and industrial pharmacy》 |2014年第6期|共10页
作者
Dani Prateek; Puri Vibha; Bansal A. K.;
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正文语种 eng
中图分类药学;
关键词
Amorphous solid dispersion; enthalpy relaxation; etoricoxib; kinetic solubility; physical stability; recrystallization;

机译：非晶态固体分散体;焓松弛;依托昔布;动力学溶解度;物理稳定性;重结晶;

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专利

1. Solubility advantage from amorphous etoricoxib solid dispersions [J] . Dani Prateek, Puri Vibha, Bansal A. K. Drug development and industrial pharmacy . 2014,第1a6期

机译：无定形依托昔布固体分散体的溶解度优势
2. Re-evaluating the presumed superiority of amorphous nanoparticles over amorphous microscale solid dispersion in solubility enhancement of poorly soluble drugs [J] . Li Ming Lim, The-Thien Tran, Wean Sin Cheow, European journal of pharmaceutical sciences . 2017,第期

机译：在溶解性增强中，重新评估非晶纳米粒子的假物纳米粒子的假定优势，可溶于可溶性药物
3. Oral bioavailability enhancement of β-lapachone, a poorly soluble fast crystallizer, by cocrystal, amorphous solid dispersion, and crystalline solid dispersion [J] . Chengyu Liu, Zhengsheng Liu, Yuejie Chen, European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fuer Pharmazeutische Verfahrenstechnik e.V . 2018,第期

机译：口服生物利用度增强β-乙酰酮，易溶性快速结晶器，通过Cocrystal，无定形固体分散体和结晶固体分散体
4. Development of Clinical Dosage Forms for a Poorly Water-Soluble Drug II: Comparative Evaluation of Solid Dispersion, Solid Microemulsion Preconcentrate and Lipid-based Formulations [C] . Rose-Marie Dannenfelser, Handan He, Ping Li, Controlled Release Society Annual Meeting and Exposition . 2007

机译：水溶性差的药物的临床剂型开发II：固体分散体，固体微乳液预浓缩物和脂质基制剂的比较评价
5. Investigation of Amorphous Solid Dispersions for Solubility Enhancement of Poorly Water-Soluble Drugs: Understanding the Effect of Material Properties on Amorphous Drug Crystallization and the Impact on Formulation Performance [D] . Ojo, Andrew Olutoye. 2021

机译：对水溶性药物溶解性增强的无定形固体分散体的研究：了解材料性质对非晶药物结晶的影响及对配制性能的影响
6. Solubility and Dissolution Enhancement of Etoricoxib by Solid Dispersion Technique Using Sugar Carriers [O] . Abhisekh Das, Amit Kumar Nayak, Biswaranjan Mohanty, 2011

机译：糖载体的固体分散技术提高依托考昔的溶解度和溶解度
7. Enhancement of Aqueous Solubility and Dissolution Rate of Etoricoxib by Solid Dispersion Technique [O] . Mustapha M. AlKhalidi, Fatima J. Jawad 2020

机译：通过固体分散技术提高肉毒毒素水溶性和溶出速率

Solubility advantage from amorphous etoricoxib solid dispersions

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