A 42-year-old man underwent esophagogas-troduodenoscopy (EGD) at our institute for melena with severe anemization. A giant polypoid lesion with some superficial erosions was found at the proximal descending part of duodenum, next to the upper angle. The lesion had a maximum transverse diameter of 4 cm, with an overall length of 7 cm (Figure l(a)). Histology revealed Brunner's gland hyperplasia.
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