Liquid preparations should be a high priority

摘要

The method of preparing levothyroxine solution suggested by James Wells (PJ,11 December,p852) is impractical for extemporaneous dispensing in the hospital or community pharmacy and has great potential for error if pure drug is used.The quantity of pure drug required for 100ml of solution of the strength stated is only Img and would require weighing of a much larger amount,measurement of aliquots from a solution and further dilution.Furthermore,no evidence of stability has been provided with the suggested method.