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Surgical Treatment of Dystonia

机译:肌张力障碍的外科治疗

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摘要

Dystonia, defined as a disorder of sustained muscular contraction leading to abnormal postures and twisting movements, has evoked both fascination and frustration from neurosurgeons for decades. Many procedures have been tried for the many types of dystonia, including myectomies, selective denervation, decompression, ablative lesions, and deep brain stimulation. Success of these surgical approaches must be weighed against the relatively bleak outcome for generalized dystonia and the striking efficacy of botulinum toxin injection in focal dystonia. The modem armamentarium includes selective peripheral denervation for spasmodic torticollis and thalamic or pallidal stimulation, and the neurosurgeon must choose a procedure based on reports of its past success. The author reviews these reports of the procedures currently available for the treatment of dystonia.
机译:肌张力障碍定义为持续性肌肉收缩导致的异常姿势和扭曲运动的疾病,数十年来一直引起神经外科医生的迷恋和沮丧。已经针对多种类型的肌张力障碍尝试了许多手术方法,包括肌切开,选择性去神经支配,减压,消融性病变和深部脑刺激。必须权衡这些手术方法的成功与广泛性肌张力障碍相对惨淡的结果以及肉毒杆菌毒素注射在局灶性肌张力障碍中的惊人功效。现代武器库包括针对痉挛性斜颈和丘脑或苍白球刺激的选择性外周神经支配,神经外科医生必须根据其过去成功的报道来选择一种手术方法。作者回顾了有关目前可用于肌张力障碍治疗的程序的这些报告。

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