We much appreciate the forward-looking thoughts and encouragement provided by the authors of the invited commentary on our article. We completely agree that the small number of animals is a major limitation of our experiment. However, as well pointed out in the comment, this was just a first step toward what we believe is the right direction. Although still in its earlier phases of development, the full integration of image-guidance techniques in minimally invasive surgery bears the potential to benefit prostate cancer patients by increasing the precision of surgical procedures.
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