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Molecular Therapy - Oncolytics

中文名称：分子疗法-溶瘤药

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1.Insulin and Metformin Control Cell Proliferation by Regulating TDG-Mediated DNA Demethylation in Liver and Breast Cancer Cells

机译：通过调节肝脏和乳腺癌细胞中的TDG介导的DNA去甲基化胰岛素和二甲双胍控制细胞增殖
- 作者：Jia-Bao Yan;Chien-Cheng Lai;Jin-Wei Jhu;Brendan Gongol;Traci L. Marin;Shih-Chieh Lin;Hsiang-Yi Chiu;Chia-Jui Yen;Liang-Yi Wang;I-Chen Peng
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- insulinmetforminc-MycAMPKTDGDNA demethylationSREBP1cancerdiabetes;
2.Efficacy and Safety of CD28- or 4-1BB-Based CD19 CAR-T Cells in B Cell Acute Lymphoblastic Leukemia

机译：CD28-或基于4-1bb的CD19 CAR-T细胞在B细胞急性淋巴细胞白血病中的疗效和安全性
- 作者：Xiangyu Zhao;Junfang Yang;Xian Zhang;Xin-An Lu;Min Xiong;Jianping Zhang;Xiaosu Zhou;Feifei Qi;Ting He;Yanping Ding;Xuelian Hu;Floris De Smet;Peihua Lu;Xiaojun Huang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- CAR-Tco-stimulatory domainB-ALL therapydose;
3.Collateral Lethal Effects of Complementary Oncolytic Viruses

机译：互补溶血病毒的抵押致命作用
- 作者：Justin W. Maroun;Velia Penza;Taylor M. Weiskittel;Autumn J. Schulze;Stephen J. Russell
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- Oncolytic virusVaccinia virusVesicular Stomatitis virusMengovirusAntiviral Immunity;
4.Boosting Replication and Penetration of Oncolytic Adenovirus by Paclitaxel Eradicate Peritoneal Metastasis of Gastric Cancer

机译：通过紫杉醇根除胃癌腹膜转移的植物腺瘤的复制和渗透
- 作者：Wataru Ishikawa;Satoru Kikuchi;Toshihiro Ogawa;Motoyasu Tabuchi;Hiroshi Tazawa;Shinji Kuroda;Kazuhiro Noma;Masahiko Nishizaki;Shunsuke Kagawa;Yasuo Urata;Toshiyoshi Fujiwara
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- peritoneal metastasisadenovirusgastric cancerintraperitoneal chemotherapypaclitaxeloncolytic virus;
5.An Artificial CTCF Peptide Triggers Efficient Therapeutic Efficacy in Ocular Melanoma

机译：人造CTCF肽在眼黑素瘤中触发有效的治疗疗效
- 作者：Xuyang Wen;Huixue Wang;Peiwei Chai;Jiayan Fan;Xiaoyu Zhang;Tianyi Ding;Renbing Jia;Shengfang Ge;He Zhang;Xianqun Fan
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- decoy CTCFocular melanomatherapeutic efficacy;
6.Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model

机译：神经干细胞在转移性卵巢癌模型中改善溶解嵌入的嵌合嵌合正毒oxvirus的递送
- 作者：Mohamed Hammad;Yvonne R. Cornejo;Jennifer Batalla-Covello;Asma Abdul Majid;Connor Burke;Zheng Liu;Yate-Ching Yuan;Min Li;Thanh H. Dellinger;Jianming Lu;Nanhai G. Chen;Yuman Fong;Karen S. Aboody;Rachael Mooney
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolytic virotherapyCF33ovarian cancerneural stem cellscellular therapyCancerOncolysisOncolytic virusImmunityImmunotherapy;
7.CD133 mRNA-Loaded Dendritic Cell Vaccination Abrogates Glioma Stem Cell Propagation in Humanized Glioblastoma Mouse Model

机译：CD133加载的树突式细胞疫苗接种消除人源性胶质母细胞瘤小鼠模型中的胶质瘤干细胞繁殖
- 作者：Angelique Sao-Mai Sy Do;Takayuki Amano;Lincoln A. Edwards;Lei Zhang;Mariza De Peralta-Venturina;John S. Yu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- CD133GBMdendritic cell vaccinehumanized mouse model;
8.Cetuximab-Triptolide Conjugate Suppresses the Growth of EGFR-Overexpressing Lung Cancers through Targeting RNA Polymerase II

机译：甲磺酸酯缀合物通过靶向RNA聚合酶II抑制EGFR过表达肺癌的生长
- 作者：Keqiang Zhang;Yuelong Ma;Yuming Guo;Ting Sun;Jun Wu;Rajendra P. Pangeni;Min Lin;Wendong Li;David Horne;Dan J. Raz
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- antibody-drug conjugatetargeted therapytriptolidecetuximabEGFRNSCLCRNA polymerase IIhistone H3 lysine methylation;
9.Myxoma Virus-Loaded Mesenchymal Stem Cells in Experimental Oncolytic Therapy of Murine Pulmonary Melanoma

机译：Myxoma病毒负载的间充质干细胞在鼠肺黑色素瘤的实验性溶解中
- 作者：Joanna Jazowiecka-Rakus;Aleksander Sochanik;Aleksandra Rusin;Agata Hadry?;Wojciech Fidyk;Nancy Villa;Masmudur M. Rahman;Ewa Chmielik;Lina S. Franco;Grant McFadden
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- mesenchymal stem cellsmyxoma virusmelanomaoncolytic virotherapy;
10.LGR6 Promotes Tumor Proliferation and Metastasis through Wnt/β-Catenin Signaling in Triple-Negative Breast Cancer

机译：LGR6通过三阴性乳腺癌中的Wnt /β-catenin信号传导促进肿瘤增殖和转移
- 作者：Yanan Kong;Xueqi Ou;Xing Li;Yan Zeng;Guanfeng Gao;Ning Lyu;Peng Liu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
11.Analysis and Augmentation of the Immunologic Bystander Effects of CAR T Cell Therapy in a Syngeneic Mouse Cancer Model

机译：CAR T细胞疗法在同鼠癌模型中的免疫旁观者效应分析及增强
- 作者：Astero Klampatsa;Michael S. Leibowitz;Jing Sun;Maria Liousia;Evguenia Arguiri;Steven M. Albelda
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
12.miR-324-5p Contributes to Cell Proliferation and Apoptosis in Pancreatic Cancer by Targeting KLF3

机译：MiR-324-5P通过靶向KLF3有助于细胞增殖和胰腺癌细胞凋亡
- 作者：Yiyuan Wan;Hesheng Luo;Ming Yang;Xia Tian;Bo Peng;Ting Zhan;Xiaoli Chen;Yu Ding;Jinrong He;Xueting Cheng;Xiaodong Huang;Yadong Zhang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- miR-324-5pKLF3proliferationapoptosispancreatic cancer;
13.Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy

机译：基于用于免疫疗法的人T细胞受体的增强性亲和力结合的分子规则
- 作者：Rory M. Crean;Bruce J. MacLachlan;Florian Madura;Thomas Whalley;Pierre J. Rizkallah;Christopher J. Holland;Catriona McMurran;Stephen Harper;Andrew Godkin;Andrew K. Sewell;Christopher R. Pudney;Marc W. van der Kamp;David K. Cole
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- T cellscancer immunotherapypeptide-human leukocyte antigenpHLAT cell receptorTCRmolecular dynamicsMDsimulationsX-ray crystallography;
14.Development of a Novel Class of Self-Assembling dsRNA Cancer Therapeutics: A Proof-of-Concept Investigation

机译：开发一种新型自组装DSRNA癌症治疗方法：概念验证调查
- 作者：Vishwaratn Asthana;Brett S. Stern;Yuqi Tang;Pallavi Bugga;Ang Li;Adam Ferguson;Anantratn Asthana;Gang Bao;Rebekah A. Drezek
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
15.Regulating Stem Cell-Related Genes Induces the Plastic Differentiation of Cancer Stem Cells to Treat Breast Cancer

机译：调节干细胞相关基因诱导癌症干细胞的塑性分化治疗乳腺癌
- 作者：Jing-Ying Zhang;Qian Luo;Jia-Rui Xu;Jing Bai;Li-Min Mu;Yan Yan;Jia-Lun Duan;Yi-Nuo Cui;Zhan-Bo Su;Ying Xie;Wan-Liang Lu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- cancer stem cellsplastic differentiationsalinomycinstem cell-related genesPKC α signaling pathway;
16.Endoscopic Molecular Imaging plus Photoimmunotherapy: A New Strategy for Monitoring and Treatment of Bladder Cancer

机译：内窥镜分子成像加光汞疗法：一种新的监测和治疗膀胱癌的新策略
- 作者：Yongjun Yang;Chao Liu;Xiaofeng Yang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- bladder cancerendoscopic molecular imagingphotoimmunotherapydiagnosis and treatmentprecision medicine;
17.Irisin Is a Positive Regulator for Ferroptosis in Pancreatic Cancer

机译：Irisin是胰腺癌中的硬质裂菌阳性调节因子
- 作者：Bao Chen Yang;Po Sing Leung
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- autophagyerastinferroptosisirisinPANC-1 cellsROS;
18.Overexpression of miR-382 Sensitizes Hepatocellular Carcinoma Cells to γδ T Cells by Inhibiting the Expression of c-FLIP

机译：MiR-382的过表达通过抑制C-Flip的表达，使肝细胞癌细胞敏感至γδT细胞
- 作者：Zhong Chen;Zhiang Zheng;Lan Feng;Zhenqing Huo;Liju Huang;Mingchang Fu;Qiuzan Chen;YanZhuang Ke;Jinjun Yang;Benxin Hou
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- hepatocellular carcinomaγδ T cellsmiR-382c-FLIPcaspase 8;
19.Design of an Interferon-Resistant Oncolytic HSV-1 Incorporating Redundant Safety Modalities for Improved Tolerability

机译：设计耐粘连性的耐粘性安全模型的干扰素的HSV-1，以改善耐受性
- 作者：Edward M. Kennedy;Terry Farkaly;Peter Grzesik;Jennifer Lee;Agnieszka Denslow;Jacqueline Hewett;Jeffrey Bryant;Prajna Behara;Caitlin Goshert;Daniel Wambua;Ana De Almeida;Judith Jacques;Damian Deavall;James B. Rottman;Joseph C. Glorioso;Mitchell H. Finer;Brian B. Haines;Christophe Quéva;Lorena Lerner
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolytic virusvirotherapyHSV-1microRNA attenuationcancerinterferon;
20.A Novel Aurora Kinase Inhibitor Attenuates Leukemic Cell Proliferation Induced by Mesenchymal Stem Cells

机译：一种新型的Aurora激酶抑制剂衰减由间充质干细胞诱导的白血病细胞增殖
- 作者：Jun-Dan Wang;Wei Zhang;Jing-Wen Zhang;Ling Zhang;Le-Xun Wang;Hong-Sheng Zhou;Liang Long;Gui Lu;Quentin Liu;Zi-Jie Long
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- Aurora kinase inhibitorAMLleukemic microenvironmentcell proliferation;
21.CAR-T Cells Targeting Epstein-Barr Virus gp350 Validated in a Humanized Mouse Model of EBV Infection and Lymphoproliferative Disease

机译：靶向Epstein-BARR病毒GP350的CAR-T细胞在eBV感染和淋巴抑制性疾病的人源化小鼠模型中验证
- 作者：Constanze Slabik;Maja Kalbarczyk;Simon Danisch;Reinhard Zeidler;Frank Klawonn;Valery Volk;Nicole Kr?nke;Friedrich Feuerhake;Constanca Ferreira de Figueiredo;Rainer Blasczyk;Henning Olbrich;Sebastian J. Theobald;Andreas Schneider;Arnold Ganser;Constantin von Kaisenberg;Stefan Lienenklaus;Andre Bleich;Wolfgang Hammerschmidt;Renata Stripecke
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- CAR-T cellsEBVlymphomatransplantationPTLDhumanized micegp350lymphoproliferationlytic infectionadoptive T cell therapy;
22.Biodistribution Analysis of Oncolytic Adenoviruses in Canine Patient Necropsy Samples Treated with Cellular Virotherapy

机译：用细胞病毒治疗犬患者患者尸检样品癌腺病毒的生物分布分析
- 作者：Ana Gómez;David Sardón;Teresa Cejalvo;Fernando Vázquez;Javier García-Castro;Ana Judith Perisé-Barrios
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- adenovirusoncolyticbiodistributionCelyvirimmunotherapyvirotherapy;
23.Oncolytic Virus with Attributes of Vesicular Stomatitis Virus and Measles Virus in Hepatobiliary and Pancreatic Cancers

机译：具有肝胆道和胰腺癌症的囊泡口炎病毒和麻疹病毒的溶瘤病毒
- 作者：Bolni Marius Nagalo;Camilo Ayala Breton;Yumei Zhou;Mansi Arora;James M. Bogenberger;Oumar Barro;Michael B. Steele;Nathan J. Jenks;Alexander T. Baker;Dan G. Duda;Lewis Rowland Roberts;Stephen J. Russell;Kah Whye Peng;Mitesh J. Borad
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- hepatobiliary cancermeasles virusoncolytic viral therapypancreatic cancervesicular stomatitis virushepatocellular carcinomacholangiocarcinoma;
24.Doxorubicin Conjugation to Reovirus Improves Oncolytic Efficacy in Triple-Negative Breast Cancer

机译：转载对reovirus的缀合可提高三阴性乳腺癌中的溶血疗效
- 作者：Jameson T.L. Berry;Luis E. Mu?oz;Roxana M. Rodríguez Stewart;Periasamy Selvaraj;Bernardo A. Mainou
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolyticsvirustriple-negative breast cancerdoxorubicinreoviruscell deathDNA damagedrug deliveryvirus-host interactions;
25.Chimeric Antigen Receptor T Cell Therapy Targeting ICAM-1 in Gastric Cancer

机译：嵌合抗原受体T细胞疗法靶向ICAM-1在胃癌中
- 作者：Minkyu Jung;Yanping Yang;Jaclyn E. McCloskey;Marjan Zaman;Yogindra Vedvyas;Xianglan Zhang;Dessislava Stefanova;Katherine D. Gray;Irene M. Min;Raza Zarnegar;Yoon Young Choi;Jae-Ho Cheong;Sung Hoon Noh;Sun Young Rha;Hyun Cheol Chung;Moonsoo M. Jin
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- Chimeric antigen receptorGastric cancerT cell imaginginducible cytokines;
26.Neoadjuvant Use of Oncolytic Herpes Virus G47Δ Enhances the Antitumor Efficacy of Radiofrequency Ablation

机译：Neoadjuvant of incolytic疱疹病毒g47δ增强了射频消融的抗肿瘤效果
- 作者：Tomoharu Yamada;Ryosuke Tateishi;Miwako Iwai;Kazuhiko Koike;Tomoki Todo
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- Oncolytic virusG47Δradiofrequency ablationhepatocellular carcinomaimmune checkpoint inhibitorherpes simplex virus type 1neoadjuvant;
27.Ablation of Stromal Cells with a Targeted Proapoptotic Peptide Suppresses Cancer Chemotherapy Resistance and Metastasis

机译：用靶向凋亡肽的基质细胞消融抑制癌症化疗抗性和转移
- 作者：Fei Su;Xiaoping Wang;Troy Pearson;Jangsoon Lee;Savitri Krishnamurthy;Naoto T. Ueno;Mikhail G. Kolonin
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- peptidetargetingcancerbreastobesityadipose stromal cellcancer fibroblastEMTchemotherapymetastasis;
28.High Oncolytic Activity of a Double-Deleted Vaccinia Virus Copenhagen Strain against Malignant Pleural Mesothelioma

机译：双缺失的痘苗病毒蛋白清干酪菌株对恶性胸膜间皮瘤的高溶瘤活性
- 作者：Tiphaine Delaunay;Joelle Nader;Marion Grard;Isabelle Farine;Vera Hedwig;Johann Foloppe;Thibaut Blondy;Mathilde Violland;Daniel Pouliquen;Marc Grégoire;Nicolas Boisgerault;Philippe Erbs;Jean-Fran?ois Fonteneau
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolytic immunotherapyoncolytic virusvaccinia viruspleural mesotheliomathymidine kinaseribonucleotide reductase;
29.HDAC Inhibitor LBH589 Suppresses the Proliferation but Enhances the Antileukemic Effect of Human γδT Cells

机译：HDAC抑制剂LBH589抑制增殖，但增强了人γΔT细胞的抗血血效应
- 作者：Ying He;Lin Xu;Jingjing Feng;Kangni Wu;Yanmin Zhao;He Huang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- HDAC inhibitorhuman γδT cellproliferationantileukemic activity;
30.A Screened GPR1 Peptide Exerts Antitumor Effects on Triple-Negative Breast Cancer

机译：筛选的GPR1肽对三阴性乳腺癌产生抗肿瘤作用
- 作者：Chen Huang;Xiao-Yong Dai;Jia-Xuan Cai;Jie Chen;Bao Bei Wang;Wen Zhu;Esther Wang;Wei Wei;Jian V. Zhang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
31.Valeric Acid Suppresses Liver Cancer Development by Acting as a Novel HDAC Inhibitor

机译：valeric酸通过作为新的HDAC抑制剂而抑制肝癌发育
- 作者：Rui Han;Olivia Nusbaum;Xinyi Chen;Yong Zhu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- valeric acidhepatocellular carcinomalipid nanoparticleHDACiapoptosiscell proliferationcolony formationcell migration3D formationmouse model;
32.Inhibition of Autophagy Amplifies Baicalein-Induced Apoptosis in Human Colorectal Cancer

机译：抑制自噬放大了人结直肠癌中的BaiCalein诱导的细胞凋亡
- 作者：Thuy Phan;Vu H. Nguyen;Marcela A’lincourt Salazar;Paul Wong;Don J. Diamond;John H. Yim;Laleh G. Melstrom
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- baicaleincolorectal cancerautophagychloroquineapoptosis;
33.PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model

机译：PSMA定向的汽车T细胞与低剂量多西紫杉醇治疗结合在前列腺癌异种移植模型中诱导肿瘤回归
- 作者：Jamal Alzubi;Viviane Dettmer-Monaco;Johannes Kuehle;Niko Thorausch;Maximilian Seidl;Sanaz Taromi;Wolfgang Schamel;Robert Zeiser;Hinrich Abken;Toni Cathomen;Philipp Wolf
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- CAR T cellsprostate cancerfocal therapydocetaxelchemotherapycombination therapyprostate specific membrane antigen;
34.Non-signaling Chimeric Antigen Receptors Enhance Antigen-Directed Killing by γδ T Cells in Contrast to αβ T Cells

机译：非信号嵌合抗原受体通过与αβT细胞相比，通过γδT细胞增强抗原定向杀伤
- 作者：Lauren C. Fleischer;Scott A. Becker;Rebecca E. Ryan;Andrew Fedanov;Christopher B. Doering;H. Trent Spencer
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- chimeric antigen receptorCARnon-stimulating chimeric antigen receptorNSCARanti-CD5CARgamma delta T cellsCD19 nonstimulating CAR;
35.CXCR4 Antagonist AMD3100 Reverses the Resistance to Tamoxifen in Breast Cancer via Inhibiting AKT Phosphorylation

机译：CXCR4拮抗剂AMD3100通过抑制AKT磷酸化反转乳腺癌中的抗毒素的抗性
- 作者：Jun Zhou;Kehao Le;Ming Xu;Jie Ming;Wen Yang;Qiulei Zhang;Linlin Lu;Zihan Xi;Shengnan Ruan;Tao Huang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- breast cancertamoxifen resistanceCXCR4AMD3100AKT phosphorylation;
36.Lactate Dehydrogenase A Depletion Alters MyC-CaP Tumor Metabolism, Microenvironment, and CAR T Cell Therapy

机译：乳酸脱氢酶耗尽改变了Myc-Cap肿瘤代谢，微环境和汽车T细胞疗法
- 作者：Mayuresh M. Mane;Ivan J. Cohen;Ellen Ackerstaff;Khalid Shalaby;Jenny N. Ijoma;Myat Ko;Masatomo Maeda;Avi S. Albeg;Kiranmayi Vemuri;Jaya Satagopan;Anna Moroz;Juan Zurita;Larissa Shenker;Masahiro Shindo;Tanner Nickles;Ekaterina Nikolov;Maxim A. Moroz;Jason A. Koutcher;Inna Serganova;Vladimir Ponomarev
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- lactate dehydrogenase ALDH-Alactatehuman prostate-specific membrane antigenhPSMAbioluminescence imagingBLIluciferase reportersprostate cancertumor microenvironmentTMEtumor metabolismmagnetic resonance spectroscopyMRSchimeric antigen receptorCART cells;
37.Polymethine Dye-Functionalized Nanoparticles for Targeting CML Stem Cells

机译：用于靶向CML干细胞的聚甲素染料官能化纳米颗粒
- 作者：Philipp Ernst;Adrian T. Press;Mike Fischer;Vivien Günther;Christine Gr?fe;Joachim H. Clement;Thomas Ernst;Ulrich S. Schubert;Jana Wotschadlo;Marc Lehmann;Christoph Enzensperger;Michael Bauer;Andreas Hochhaus
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- polymethine dyesnanoparticlesCMLOATP1B3OCT1;
38.Artificial T Cell Adaptor Molecule-Transduced TCR-T Cells Demonstrated Improved Proliferation Only When Transduced in a Higher Intensity

机译：人造T细胞衔接子分子转导的TCR-T细胞仅在更高强度转导时显示出改善的增殖
- 作者：Toshiyasu Sakai;Seitaro Terakura;Kotaro Miyao;Shingo Okuno;Yoshitaka Adachi;Koji Umemura;Jakrawadee Julamanee;Keisuke Watanabe;Hiroshi Hamana;Hiroyuki Kishi;Judith Leitner;Peter Steinberger;Tetsuya Nishida;Makoto Murata;Hitoshi Kiyoi
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- T cell receptor gene insertionartificial adaptor moleculegene-modified T cell therapyCD3ζ gene modificationadaptor molecule gene-insertion intensity;
39.FOXA1 Regulation Turns Benzamide HDACi Treatment Effect-Specific in BC, Promoting NIS Gene-Mediated Targeted Radioiodine Therapy

机译：FOXA1调节转动BC中特异性苯甲酰胺HDACI治疗效果，促进NIS基因介导的靶向放射性碘治疗
- 作者：Maitreyi Rathod;Madhura Kelkar;Snehal Valvi;Girish Salve;Abhijit De
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- sodium iodide symporterbreast cancerbenzamideHDAC inhibitortranscriptional factorradio-iodine therapyFOXA1;
40.Repurposing Pimavanserin, an Anti-Parkinson Drug for Pancreatic Cancer Therapy

机译：重新培养Pimavanserin，一种用于胰腺癌治疗的抗帕金森药物
- 作者：Sharavan Ramachandran;Sanjay K. Srivastava
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- pimavanserinpancreatic cancerAktstem cellsdrug repurposingorthotopic tumorsGli1c-Mycapoptosis;
41.Preclinical Evaluation of the Oncolytic Vaccinia Virus TG6002 by Translational Research on Canine Breast Cancer

机译：甘氨酸乳腺癌翻译研究癌症疫苗病毒TG6002的临床前评价
- 作者：Jérémy Béguin;Johann Foloppe;Christelle Maurey;Eve Laloy;Julie Hortelano;Virginie Nourtier;Christelle Pichon;Sandrine Cochin;Pascale Cordier;Hélène Huet;Eric Quemeneur;Bernard Klonjkowski;Philippe Erbs
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolytic virotherapyvaccinia virusTG6002FCU1suicide gene therapymammary tumordogtranslational research5-fluorouracil;
42.Antitumor Activity In?Vivo and Vitro of New Chiral Derivatives of Baicalin and Induced Apoptosis via the PI3K/Akt Signaling Pathway

机译：抗肿瘤活性在β-生物细胞素的体外活性，通过PI3K / AKT信号通路诱导细胞凋亡
- 作者：Yi Hou;Chao Pi;Xianhu Feng;Yuanyuan Wang;Shaozhi Fu;Xiaomei Zhang;Ling Zhao;Yumeng Wei
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- baicalinchiral derivativesPI3K/Akt signaling pathwayapoptosislung cancermolecular docking technology;
43.A 70-Gene Signature for Predicting Treatment Outcome in Advanced-Stage Cervical Cancer

机译：预测晚期宫颈癌治疗结果的70基因签名
- 作者：Ngoc Ngo Yen Nguyen;Tae Gyu Choi;Jieun Kim;Min Hyung Jung;Seok Hoon Ko;Yoonhwa Shin;Insug Kang;Joohun Ha;Sung Soo Kim;Yong Hwa Jo
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- cervical cancergene signaturesurvivaladvanced stagemolecular-targeted therapy;
44.Arming HSV-Based Oncolytic Viruses with the Ability to Redirect the Host’s Innate Antiviral Immunity to Attack Tumor Cells

机译：基于HSV的灰熊酵母病毒，具有重定向宿主的先天抗病毒免疫力来攻击肿瘤细胞的能力
- 作者：Xinping Fu;Lihua Tao;Wanfu Wu;Xiaoliu Zhang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
45.A New Tool for CRISPR-Cas13a-Based Cancer Gene Therapy

机译：CRISPR-CAS13A基础癌症基因治疗的新工具
- 作者：Jinliang Gao;Tao Luo;Na Lin;Shuyan Zhang;Jinke Wang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- CRISPR-Cas13aNF-κBRNA interferencecancergene therapy;
46.Exploring the Role of TRIP-Brs in Human Breast Cancer: An Investigation of Expression, Clinicopathological Significance, and Prognosis

机译：探索行程 - BRS在人乳腺癌中的作用：表达，临床病理意义和预后的调查
- 作者：Raj Kumar Mongre;Chandra Bhushan Mishra;Samil Jung;Beom Suk Lee;Nguyen Thi Ngoc Quynh;Nguyen Hai Anh;Davaajragal Myagmarjav;Taeyeon Jo;Myeong-Sok Lee
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- transcription factorsTRIP-BrsBRCAmutationclinicopathologicalpatient survivaltumor-infiltrating immune cellsKEGG pathways;
47.Live Attenuated Measles Virus Vaccine Expressing Helicobacter pylori Heat Shock Protein A

机译：现场减毒麻疹病毒疫苗表达幽门螺杆菌热休克蛋白A.
- 作者：Ianko D. Iankov;Cheyne Kurokawa;Kimberly Viker;Steven I. Robinson;Arun Ammayappan;Eleni Panagioti;Mark J. Federspiel;Evanthia Galanis
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- measles virusoncolytic agentHelicobacter pyloriheat-shock protein Avaccineimmune responseimmune check point;
48.Recombinant SLAMblind Measles Virus Is a Promising Candidate for Nectin-4-Positive Triple Negative Breast Cancer Therapy

机译：重组倾斜麻疹病毒是Nectin-4阳性三重阴性乳腺癌治疗的有希望的候选者
- 作者：Tomoko Fujiyuki;Yosuke Amagai;Koichiro Shoji;Takeshi Kuraishi;Akihiro Sugai;Mutsumi Awano;Hiroki Sato;Shosaku Hattori;Misako Yoneda;Chieko Kai
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- measles virusoncovirotherapytriple negative breast cancernectin-4oncolytic virussafetynon-human primateintravenoussystemic;
49.S119N Mutation of the E3?Ubiquitin Ligase SPOP Suppresses SLC7A1 Degradation to Regulate Hepatoblastoma Progression

机译：E3的S119N突变？泛素连接酶孢子抑制SLC7A1降解以调节肝细胞瘤进展
- 作者：Weijing He;Jingjing Zhang;Baihui Liu;Xiangqi Liu;Gongbao Liu;Lulu Xie;Jiajun He;Meng Wei;Kai Li;Jing Ma;Rui Dong;Duan Ma;Kuiran Dong;Mujie Ye
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- amino acid metabolismepithelial-mesenchymal transitionhepatoblastomamutationubiquitin degradation;
50.hsa_circ_0085539 Promotes Osteosarcoma Progression by Regulating miR-526b-5p and SERP1

机译：HSA_CIRC_0085539通过调节MIR-526B-5P和SERP1来促进骨肉瘤进展
- 作者：Wei Liu;Dunwei Wang;Xu Wang;Pengcheng Liu;Ming Yan
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- hsa_circ_0085539miR-526b-5pSERP1osteosarcoma;
51.Heterologous Prime Boost Vaccination Induces Protective Melanoma-Specific CD8+ T Cell Responses

机译：异源素促促疫苗接种诱导保护黑色素瘤特异性CD8 + T细胞反应
- 作者：Sandra S. Ring;Micha? Królik;Fabienne Hartmann;Erika Schmidt;Omar Hasan Ali;Burkhard Ludewig;Stefan Kochanek;Lukas Flatz
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- Cancer vaccinationViral VectorsMelanomagp100heterologous prime boost;
52.Mesenchymal Stem Cell-Secreted Exosome Promotes Chemoresistance in Breast Cancer via Enhancing miR-21-5p-Mediated S100A6 Expression

机译：间充质干细胞分泌的外泌体通过增强miR-21-5p介导的S100A6表达促进乳腺癌中的化学化学
- 作者：Tao Luo;Qiaoyuan Liu;Aihua Tan;Lixia Duan;Yuxian Jia;Li Nong;Jing Tang;Wenxian Zhou;Weimin Xie;Yongkui Lu;Qiang Yu;Yan Liu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- doxorubicin resistancemesenchymal stem cell exosomemiR-21-5pS100A6breast cancer;
53.Association of MicroRNA-21 with p53 at Mutant Sites R175H and R248Q, Clinicopathological Features, and Prognosis of NSCLC

机译：MicroRNA-21与p53在突变位点的关联R175H和R248Q，临床病理特征，NSCLC预后
- 作者：Yaodong Zhou;Dongdong Guo;Yixin Zhang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- non-small cell lung cancermiR-21p53knockdownprognosisinteraction;
54.Decreasing the Susceptibility of Malignant Cells to Infection Does Not Impact the Overall Efficacy of Myxoma Virus-Based Oncolytic Virotherapy

机译：降低恶性细胞对感染的易感性不会影响肌瘤病毒的溶瘤病毒的整体疗效
- 作者：Erica B. Flores;Eric Bartee
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolytic virotherapyviral dosingimmunotherapy;
55.Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment

机译：重新靶向和多细胞因子武装疱疹病毒是局部和全身抗肿瘤治疗的强癌骨内膜
- 作者：Maria De Lucia;Gabriella Cotugno;Veronica Bignone;Irene Garzia;Linda Nocchi;Francesca Langone;Biljana Petrovic;Emanuele Sasso;Simona Pepe;Guendalina Froechlich;Chiara Gentile;Nicola Zambrano;Gabriella Campadelli-Fiume;Alfredo Nicosia;Elisa Scarselli;Anna Morena D’Alise
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolytic virusendovaccinecancercytokinesimmune checkpointretargeted Herpes virusIL-12GM-CSF;
56.Oncolytic Rhabdovirus Vaccine Boosts Chimeric Anti-DEC205 Priming for Effective Cancer Immunotherapy

机译：Oncolytic rhabdovirus疫苗促进嵌合抗DEC205引发，用于有效的癌症免疫疗法
- 作者：Fanny Tzelepis;Harsimrat Kaur Birdi;Anna Jirovec;Silvia Boscardin;Christiano Tanese de Souza;Mohsen Hooshyar;Andrew Chen;Keara Sutherland;Robin J. Parks;Joel Werier;Jean-Simon Diallo
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- anti-DEC205rhabdovirusoncolytic vaccineAd5prime-boostimmunotherapy;
57.Methylation of the Promoter Region of the Tight Junction Protein-1 by DNMT1 Induces EMT-like Features in Multiple Myeloma

机译：DNMT1通过DNMT1的致密接线蛋白-1的启动子区域的甲基化诱导多种骨髓瘤中的EMT样特征
- 作者：Miao Li;Lin Qi;Jing-Bo Xu;Li-Ye Zhong;Szehoi Chan;Shu-Na Chen;Xin-Rong Shao;Li-Yuan Zheng;Zhao-Xia Dong;Tian-Liang Fang;Zhi-Ying Mai;Juan Li;Yongjiang Zheng;Xing-Ding Zhang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- multiple myelomaepithelial-to-mesenchymal-transitionTJP1methylationDNMT1Cell adhension;
58.Expression of Oncolytic Adenovirus-Encoded RNAi Molecules Is Most Effective in a pri-miRNA Precursor Format

机译：在Pri-miRNA前体形式中表达onColytic腺病毒编码的RNAi分子最有效
- 作者：Tereza Brachtlova;Jan-Willem van Ginkel;Mark J. Luinenburg;Renée X. de Menezes;Danijela Koppers-Lalic;D. Michiel Pegtel;Wenliang Dong;Tanja D. de Gruijl;Victor W. van Beusechem
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolytic virusoncolytic immunotherapygene silencinggene knockdown;
59.lncRNA DUXAP8 Facilitates Multiple Malignant Phenotypes and Resistance to PARP Inhibitor in HCC via Upregulating FOXM1

机译：LNCRNA Duxap8通过上调FOXM1促进多种恶性表型和对HCC的PARP抑制剂的抵抗力
- 作者：Yu Hu;Xian Zhang;Hong-Yan Zai;Wei Jiang;Liang Xiao;Qin Zhu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- hepatocellular carcinomaDUXAP8miR-485-5pFOXM1PARP inhibitor;
60.Regulation of Glycolysis by Non-coding RNAs in Cancer: Switching on the Warburg Effect

机译：癌症中非编码RNA的糖酵解调节：在Warburg效应上切换
- 作者：Hamed Mirzaei;Michael R. Hamblin
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- glycolysisnon-coding RNAscancerWarburg effect;
61.Prognostic Implication of a Metabolism-Associated Gene Signature in Lung Adenocarcinoma

机译：肺腺癌新陈代谢相关基因签名的预后意义
- 作者：Lulu He;Jiaxian Chen;Feng Xu;Jun Li
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- lung adenocarcinomametabolismTCGAprognosisgene signature;
62.Improving the Efficacy of EGFR Inhibitors by Topical Treatment of Cutaneous Squamous Cell Carcinoma with miR-634 Ointment

机译：用miR-634软膏局部处理EGFR抑制剂的疗效。用miR-634软膏治疗皮肤鳞状细胞癌
- 作者：Jun Inoue;Kyoko Fujiwara;Hidetoshi Hamamoto;Katsunori Kobayashi;Johji Inazawa
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- miRNA therapeuticsskin cancerEGFR-TKIglutaminolysistopical treatment;
63.Novel Chimeric Poxvirus CF17 Improves Survival in a Murine Model of Intraperitoneal Ovarian Cancer Metastasis

机译：新型嵌合痘病毒CF17改善了腹膜内卵巢癌转移的小鼠模型的存活
- 作者：Mohamed Hammad;Yvonne Cornejo;Linda Flores;Caitlyn Hyde;Hoi Wa Ngai;Min Li;Thanh H. Dellinger;Jianming Lu;Nanhai G. Chen;Rachael Mooney;Karen S. Aboody;Yuman Fong
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- oncolytic virotherapychimeric poxvirusovarian cancer;
64.Upregulated CBX8 Promotes Cancer Metastasis via the WNK2/MMP2 Pathway

机译：上调CBX8通过WNK2 / MMP2途径促进癌症转移
- 作者：Yongsheng Jia;Yujun Wang;Cuicui Zhang;Mike Yue Chen
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2020年第3期
- CBX8WNK2MMP2RAC1metastasis;
65.Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of KITLG and DKK1 genes in glioma SCs in?vitro

机译：通过MSCs的旁静脉因子表现出的抗致癌活性可以通过在胶质瘤SCS中的Kitlg和DKK1基因的调节介导
- 作者：Nazneen Aslam;Elham Abusharieh;Duaa Abuarqoub;Dema Ali;Dana Al-Hattab;Suha Wehaibi;Ban Al-Kurdi;Fatima Jamali;Walhan Alshaer;Hanan Jafar;Abdalla S. Awidi
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- mesenchymal stem cellsglioma stem cellsgliospheresconditioned mediaWJ-MSCsBM-MSCsmicroarraysignaling pathwaysCSC arraysstemness;
66.Engineered CAR-T cells targeting TAG-72 and CD47 in ovarian cancer

机译：工程化的Car-T细胞靶向标签-72和CD47在卵巢癌中
- 作者：Runzhe Shu;Vera J. Evtimov;Maree V. Hammett;Nhu-Y N. Nguyen;Junli Zhuang;Peter J. Hudson;Maureen C. Howard;Aleta Pupovac;Alan O. Trounson;Richard L. Boyd
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- CAR-T cellsdual specificityovarian cancerTAG-72CD47;
67.Cancer imaging and therapy utilizing a novel NIS-expressing adenovirus: The role of adenovirus death protein deletion

机译：癌症成像和治疗利用新的NIS表达腺病毒：腺病毒死亡蛋白缺失的作用
- 作者：Matthew Glen Robertson;Benjamin Bruce Eidenschink;Eriko Iguchi;Stanislav O. Zakharkin;Christopher J. LaRocca;Ezequiel J. Tolosa;Mark J. Truty;Kari Jacobsen;Martin E. Fernandez-Zapico;Julia Davydova
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- Oncolytic VirusAdenovirusSodium-iodide symporterAdenovirus Death ProteinCancer imagingRadiotherapyPancreatic cancer;
68.A polygenic methylation prediction model associated with response to chemotherapy in epithelial ovarian cancer

机译：与上皮性卵巢癌化疗反应相关的多基甲基化预测模型
- 作者：Lanbo Zhao;Sijia Ma;Linconghua Wang;Yiran Wang;Xue Feng;Dongxin Liang;Lu Han;Min Li;Qiling Li
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- ovarian cancerbioinformaticsDNA methylationchemotherapy responseprediction modelAGR2HSPA2ACAT2;
69.CXCL2 combined with HVJ-E suppresses tumor growth and lung metastasis in breast cancer and enhances anti-PD-1 antibody therapy

机译：CXCL2与HVJ-E结合抑制乳腺癌中的肿瘤生长和肺转移，并增强抗PD-1抗体治疗
- 作者：Yi Chun Pan;Tomoyuki Nishikawa;Chin Yang Chang;Jiayu A. Tai;Yasufumi Kaneda
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- HVJ-EN1-type neutrophilsbreast cancermetastasisanti-PD-1;
70.Oncolytic vaccinia virus induces a novel phenotype of CD8 effector T?cells characterized by high ICOS expression

机译：溶氯痘病毒诱导CD8效应器T的新表型。特征在于高ICOS表达的细胞
- 作者：Midori Yamashita;Mamoru Tasaki;Ryuji Murakami;Yukinori Arai;Takafumi Nakamura;Shinsuke Nakao
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- oncolytic vaccinia virusin situ vaccinationintratumoral CD8 T cellsICOS;
71.Molecular profiles of small cell lung cancer subtypes: therapeutic implications

机译：小细胞肺癌亚型的分子曲线：治疗意义
- 作者：Anna Schwendenwein;Zsolt Megyesfalvi;Nandor Barany;Zsuzsanna Valko;Edina Bugyik;Christian Lang;Bence Ferencz;Sandor Paku;Andras Lantos;Janos Fillinger;Melinda Rezeli;Gyorgy Marko-Varga;Krisztina Bogos;Gabriella Galffy;Ferenc Renyi-Vamos;Mir Alireza Hoda;Walter Klepetko;Konrad Hoetzenecker;Viktoria Laszlo;Balazs Dome
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- small cell lung cancerheterogeneityneuroendocrinemolecular profile;
72.Tumor microenvironment and immune-related therapies of head and neck squamous cell carcinoma

机译：头颈鳞状细胞癌的肿瘤微环境和免疫相关疗法
- 作者：Yixiao Qin;Xiwang Zheng;Wei Gao;Binquan Wang;Yongyan Wu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- head and neck squamous cell carcinomatumor microenvironmentimmunotherapyPD-1PD-L1CTLA-4;
73.A novel vaccinia virus enhances anti-tumor efficacy and promotes a long-term anti-tumor response in a murine model of colorectal cancer

机译：新型痘苗病毒增强了抗肿瘤疗效，促进了结直肠癌小鼠模型中的长期抗肿瘤反应
- 作者：Na Wang;Jiwei Wang;Zhe Zhang;Hua Cao;Wenli Yan;Yongchao Chu;Louisa S. Chard Dunmall;Yaohe Wang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
74.HDAC inhibition prevents transgene expression downregulation and loss-of-function in T-cell-receptor-transduced T?cells

机译：HDAC抑制阻止转基因表达下调和在T细胞受体转导的T 2细胞中的功能丧失
- 作者：Tamson V. Moore;Gina M. Scurti;Matthew DeJong;Siao-Yi Wang;Annika V. Dalheim;Courtney R. Wagner;Kelli A. Hutchens;Jodi J. Speiser;Constantine V. Godellas;Chris Fountain;Jessica Fleser;Tarsem Moudgil;Mallory Thomas;David Murray;Brendan D. Curti;Joseph I. Clark;Bernard A. Fox;Michael I. Nishimura
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- TCR-transduced T cellsgene-modified T cellsHDAC inhibitorssodium butyratevorinostatgene silencingtransgene silencingcancer immunotherapycell therapyfunctional responses;
75.Introducing a new reporter gene, membrane-anchored Cypridina luciferase, for multiplex bioluminescence imaging

机译：介绍一种新的报告基因，膜锚固的胞质荧光素酶，用于多重生物发光成像
- 作者：Maxim A. Moroz;Juan Zurita;Anna Moroz;Ekaterina Nikolov;Yury Likar;Konstantin Dobrenkov;Jason Lee;Larissa Shenker;Ronald Blasberg;Inna Serganova;Vladimir Ponomarev
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- bioluminescence imagingBLIluciferase reportersreporter genemultiplex imaging;
76.Inhibition of tumor invasion and metastasis by targeting TGF-β-Smad-MMP2 pathway with Asiatic acid and Naringenin

机译：靶向亚胺酸和柚皮素的TGF-β-Smad-MMP2途径抑制肿瘤侵袭和转移
- 作者：Guang-Yu Lian;Qing-Ming Wang;Thomas Shiu-Kwong Mak;Xiao-Ru Huang;Xue-Qing Yu;Hui-Yao Lan
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- TGF-βmelanomalung carcinomaSmad3Smad7MMP2Asiatic acid and Naringenin;
77.MicroRNA-sensitive oncolytic measles virus for chemovirotherapy of pancreatic cancer

机译：MicroRNA敏感的胰腺癌化学治疗胰腺癌
- 作者：Hans Martin Singh;Mathias Felix Leber;Sascha Bossow;Christine E. Engeland;Jan Dessila;Christian Grossardt;Karim Zaoui;John C. Bell;Dirk J?ger;Christof von Kalle;Guy Ungerechts
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- chemovirotherapycytosine deaminasefluorouracilmeasles virusmicroRNAsmiR-148aoncolytic virusespancreatic cancerprodrugsvirotherapy;
78.Association of IDH mutation and 1p19q co-deletion with tumor immune microenvironment in lower-grade glioma

机译：IDH突变与1P19Q与肿瘤免疫微环境在较低级胶质瘤中的关联
- 作者：Wanzun Lin;Xianxin Qiu;Pian Sun;Yuling Ye;Qingting Huang;Lin Kong;Jiade J. Lu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- IDH mutations1p/19q codeletionslower-grade gliomatumor immune microenvironmentmolecular subtypesbioinformatics;
79.Nuclear export protein CSE1L interacts with P65 and promotes NSCLC growth via NF-κB/MAPK pathway

机译：核导出蛋白CSE1L与P65相互作用，通过NF-κB/ MAPK途径促进NSCLC生长
- 作者：H.C. Lin;J. Li;D.D. Cheng;X. Zhang;T. Yu;F.Y. Zhao;Q. Geng;M.X. Zhu;H.W. Kong;H. Li;M. Yao
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- CSE1LproliferationapoptosisP65MAPKNSCLC;
80.Quantitative proteomics characterization of cancer biomarkers and treatment

机译：癌症生物标志物和治疗的定量蛋白质组学表征
- 作者：Xiao-Li Yang;Yi Shi;Dan-Dan Zhang;Rui Xin;Jing Deng;Ting-Miao Wu;Hui-Min Wang;Pei-Yao Wang;Ji-Bin Liu;Wen Li;Yu-Shui Ma;Da Fu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- quantitative proteomicscancerbiomarkerdiagnostic markertherapeutic target;
81.Local administration of IL-12 with an HC vector results in local and metastatic tumor control in pediatric osteosarcoma

机译：局部施用IL-12，HC载体导致小儿骨瘤中的局部和转移性肿瘤对照
- 作者：Marta Zalacain;María Bunuales;Lucía Marrodan;Sara Labiano;Marisol Gonzalez-Huarriz;Naiara Martinez-Vélez;Virginia Laspidea;Montse Puigdelloses;Marc García-Moure;Manuela Gonzalez-Aparicio;Rubén Hernandez-Alcoceba;Marta M. Alonso;Ana Pati?o-García
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- Pediatric solid tumorstherapyosteosarcomahigh capacity adenoviral vectorsimmunotherapyIL-12;
82.Characterization of the fatty acid metabolism in colorectal cancer to guide clinical therapy

机译：结肠直肠癌脂肪酸代谢的表征引导临床治疗
- 作者：Chengsheng Ding;Zezhi Shan;Mengcheng Li;Hongqi Chen;Xinxiang Li;Zhiming Jin
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- colorectal cancerfatty acid metabolismimmuneprognosis;
83.A brief review of reporter gene imaging in oncolytic virotherapy and gene therapy

机译：浅谈Collytic病毒疗法和基因治疗中的报告基因成像
- 作者：Susanna C. Concilio;Stephen J. Russell;Kah-Whye Peng
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- bioluminescenceCerenkov luminescencefluorescencegene therapymolecular imagingmagnetic resonance imagingMRInuclear imagingoncolytic virotherapyoptical imagingphotoacoustic imagingpositron emission tomographyPETreporter gene imagingsingle photon emission computed tomographySPECTviral vectors;
84.Palmitoylated antigens for the induction of anti-tumor CD8 T?cells and enhanced tumor recognition

机译：棕榈酰基化抗原用于诱导抗肿瘤CD8 T？细胞和增强的肿瘤识别
- 作者：Dorian A. Stolk;Sophie K. Horrevorts;Sjoerd T.T. Schetters;Laura J.W. Kruijssen;Sanne Duinkerken;Eelco Keuning;Martino Ambrosini;Hakan Kalay;Rieneke van de Ven;Juan J. Garcia-Vallejo;Tanja D. de Gruijl;Sandra J. van Vliet;Yvette van Kooyk
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- mono-palmitoylationpalmitic acidpeptide modificationantigendendritic cellanti-tumorvaccinationtumor recognitionantigen enrichment;
85.lncRNA MIR503HG inhibits cell proliferation and promotes apoptosis in TNBC cells via the miR-224-5p/HOXA9 axis

机译：LNCRNA miR503Hg通过MIR-224-5P / HOXA9轴抑制细胞增殖并促进TNBC细胞中的细胞凋亡
- 作者：Shou-Man Wang;Jian Pang;Ke-Jing Zhang;Zhi-Yang Zhou;Fei-Yu Chen
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- MIR503HGtriple-negative breast cancerTNBCmiR-224-5pHOXA9lncRNA;
86.Scutellarin resensitizes oxaliplatin-resistant colorectal cancer cells to oxaliplatin treatment through inhibition of PKM2

机译：Scutellarin通过抑制PKM2将奥沙利铂抗性结肠直肠癌细胞恢复为Oxaliplatin治疗
- 作者：Wei Sun;Yang Ge;Junpeng Cui;Yifan Yu;Baolin Liu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- oxaliplatincolorectal cancerpyruvate kinase isoenzyme M2adenosine triphosphateresistanceglucosescutellarinmetabolismoverexpression;
87.A survivin-driven, tumor-activatable minicircle system for prostate cancer theranostics

机译：一种Survivin驱动的，用于前列腺癌Theranostics的肿瘤可活化的小型环保系统
- 作者：TianDuo Wang;Yuanxin Chen;David Goodale;Alison L. Allan;John A. Ronald
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- minicirclesurvivintumour-activatabletheranostic;
88.Phase I trial of oncolytic adenovirus-mediated cytotoxic and interleukin-12 gene therapy for the treatment of metastatic pancreatic cancer

机译：I型试验溶瘤腺病毒介导的细胞毒性和白细胞介素-12基因治疗用于治疗转移性胰腺癌
- 作者：Kenneth N. Barton;Farzan Siddiqui;Robert Pompa;Svend O. Freytag;Gazala Khan;Irina Dobrosotskaya;Munther Ajlouni;Yingshu Zhang;Jingfang Cheng;Benjamin Movsas;David Kwon
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- clinical trialspancreatic cancermetastasisgene therapyimmunomodulationcytokines;
89.Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus

机译：聚合物隐身和粘蛋白-1重试治疗，用于增强溶氯痘病毒病毒的药代动力学
- 作者：Claudia Hill;Megan Grundy;Luca Bau;Sheena Wallington;Joel Balkaran;Victor Ramos;Kerry Fisher;Len Seymour;Constantin Coussios;Robert Carlisle
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- vaccinia virusoncolytic virotherapypolymer coatingcholesterol-PEGtargetingmucin-1capan-2pancreatic cancer;
90.Tumor immune microenvironment-based classifications of bladder cancer for enhancing the response rate of immunotherapy

机译：基于肿瘤免疫微环境的膀胱癌分类，提高免疫疗法的反应率
- 作者：Jialin Meng;Xiaofan Lu;Yujie Zhou;Meng Zhang;Qintao Ge;Jun Zhou;Zongyao Hao;Shenglin Gao;Fangrong Yan;Chaozhao Liang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- bladder cancernon-negative matrix factorizationimmunotherapyimmune checkpoint blockade;
91.Single-cell RNA-sequencing analyses identify heterogeneity of CD8 T cell subpopulations and novel therapy targets in melanoma

机译：单细胞RNA测序分析鉴定黑素瘤CD8 T细胞群和新疗法靶标的异质性
- 作者：Weiwei Deng;Yubo Ma;Zhen Su;Yufang Liu;Panpan Liang;Chen Huang;Xiao Liu;Jin Shao;Yi Zhang;Kai Zhang;Jian Chen;Ruoyu Li
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- single-cell RNA-sequencingmelanomaCD8 T cell subpopulationsimmune checkpointsimmunotherapybioinformatics;
92.Combining vanadyl sulfate with Newcastle disease virus potentiates rapid innate immune-mediated regression with curative potential in murine cancer models

机译：将硫酸甲酰硫酸盐与新城疾病病毒相结合，增强了小鼠癌模型的疗潜力的快速先天免疫介导的回归
- 作者：Thomas M. McAusland;Jacob P. van Vloten;Lisa A. Santry;Matthew M. Guilleman;Amira D. Rghei;Edgar M. Ferreira;Joelle C. Ingrao;Rozanne Arulanandam;Pierre P. Major;Leonardo Susta;Khalil Karimi;Jean-Simon Diallo;Byram W. Bridle;Sarah K. Wootton
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- Newcastle disease virus (NDV)B16-F10vanadyl sulfatecombination therapy;
93.LINC00461 facilitates HNSCC development and reduces chemosensitivity by impairing miR-195-mediated inhibition of HOXA10

机译：LINC00461促进HNSCC开发，通过损害MIR-195介导的HOXA10抑制来减少化学敏感性
- 作者：Yifang Guan;Aizhong Guan;Long Chen;Aimei Gong
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- head and neck squamous cell carcinomalong intergenic noncoding RNA 00461microRNA-195homeobox A10epithelial-mesenchymal transitionchemoresistance;
94.Modulation of mTOR and epigenetic pathways as therapeutics in gallbladder cancer

机译：MTOR和表观遗传途径作为胆囊癌治疗剂的调节
- 作者：Dong Yang;Tao Chen;Ming Zhan;Sunwang Xu;Xiangfan Yin;Qin Liu;Wei Chen;Yunhe Zhang;Dejun Liu;Jinchun Yan;Qihong Huang;Jian Wang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
95.Upregulation of endogenous TRAIL-elicited apoptosis is essential for metformin-mediated antitumor activity against TNBC and NSCLC

机译：内源性尾流引出的细胞凋亡的上调对于抗TNBC和NSCLC的二甲双胍介导的抗肿瘤活性是必不可少的
- 作者：Shuang Liu;Erik V. Polsdofer;Lukun Zhou;Sanbao Ruan;Hui Lyu;Defu Hou;Hao Liu;Ann D. Thor;Zhimin He;Bolin Liu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- metforminTRAILapoptosisTNBCNSCLC;
96.Secretion of bispecific protein of anti-PD-1 fused with TGF-β trap enhances antitumor efficacy of CAR-T cell therapy

机译：与TGF-β陷阱融合的抗PD-1双特异性蛋白质增强了Car-T细胞疗法的抗肿瘤功效
- 作者：Xianhui Chen;Shuai Yang;Si Li;Yun Qu;Hsuan-Yao Wang;Jiangyue Liu;Zachary S. Dunn;Gunce E. Cinay;Melanie A. MacMullan;Fangheng Hu;Xiaoyang Zhang;Pin Wang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- chimeric antigen receptortumor growth factor betaimmune checkpointPD-1PD-L1tumor microenvironmentamored CAR-T cells;
97.miR-19a/b promote EMT and proliferation in glioma cells via SEPT7-AKT-NF-κB pathway

机译：miR-19a / b通过Sept7-AKT-NF-κB途径促进胶质瘤细胞的EMT和增殖
- 作者：Weihan Wang;Yubing Hao;Anling Zhang;Weidong Yang;Wei Wei;Guangxiu Wang;Zhifan Jia
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- miR-19a/bgliomaSEPT7-AKT-NF-κB pathway;
98.Association between NER pathway gene polymorphisms and neuroblastoma risk in an eastern Chinese population

机译：在华东地区人口中Ner途径基因多态性和神经母细胞瘤的关系
- 作者：Chunlei Zhou;Yizhen Wang;Lili He;Jinhong Zhu;Jinghang Li;Yingzi Tang;Haixia Zhou;Jing He;Haiyan Wu
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- nucleotide excision repairneuroblastomapolymorphismsusceptibility;
99.Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform

机译：在Pepticrad癌症疫苗平台中使用新型Ox40配体和CD40配体的CD40配体的表征
- 作者：Erkko Yl?sm?ki;Leena Yl?sm?ki;Manlio Fusciello;Beatriz Martins;Petra Ahokas;Hanne Cojoc;Arttu Uoti;Sara Feola;Anna Kreutzman;Tuuli Ranki;Julia Karbach;Tapani Viitala;Petri Priha;Elke J?ger;Sari Pesonen;Vincenzo Cerullo
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- oncolytic vaccineCD40LOX40LT cell activationPeptiCRAd;
100.Tumor-derived exosomal microRNA-7-5p enhanced by verbascoside inhibits biological behaviors of glioblastoma in?vitro and in?vivo

机译：血管内酯增强的肿瘤衍生的外泌体microRNA-7-5P抑制了体外胶质母细胞瘤的生物学行为？体内
- 作者：Huan Wang;Jiugeng Feng;Fan Ao;Yiqiang Tang;Pengliang Xu;Min Wang;Min Huang
- 期刊名称：《Molecular Therapy - Oncolytics》 | 2021年第a期
- verbascosideglioblastomamiR-7-5ptumor-derived exosomesproliferationmetastasismicrotubule formationEGFR/PI3K/Akt signaling pathway;

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