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Frontiers in Oncology

中文名称：肿瘤学前沿

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1.Combining Radiation and Immune Checkpoint Blockade in the Treatment of Head and Neck Squamous Cell Carcinoma

机译：放射线结合免疫检查点阻滞治疗头颈部鳞状细胞癌
- 作者：Gregor Manukian;Voichita Bar-Ad;Bo Lu;Athanassios Argiris;Jennifer M. Johnson
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- radiation therapyimmunotherapyimmune checkpoint inhibitorsPD1PD-L1abscopal effect;
2.Over Expressed TKTL1, CIP-2A, and B-MYB Proteins in Uterine Cervix Epithelium Scrapings as Potential Risk Predictive Biomarkers in HR-HPV-Infected LSIL/ASCUS Patients

机译：子宫宫颈上皮中过度表达的TKTL1，CIP-2A和B-MYB蛋白在HR-HPV感染的LSIL / ASCUS患者中作为潜在的风险预测生物标志物
- 作者：Anna Chiarini;Daisong Liu;Mario Rassu;Ubaldo Armato;Claudio Eccher;Ilaria Dal Prà
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- LSILASCUShuman cervical carcinomaoncogenic papillomavirusesTKTL1CIP-2aB-MYBpredictive biomarker;
3.Detection of ERBB2 (HER2) Gene Amplification Events in Cell-Free DNA and Response to Anti-HER2 Agents in a Large Asian Cancer Patient Cohort

机译：大型亚洲癌症患者队列中无细胞DNA中 ERBB2 （HER2）基因扩增事件的检测以及对抗HER2药物的反应
- 作者：Jeeyun Lee;Aleksandra Franovic;Yukimasa Shiotsu;Seung Tae Kim;Kyoung-Mee Kim;Kimberly C. Banks;Victoria M. Raymond;Richard B. Lanman
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- cfDNAERBB2HER2liquid biopsyNGS;
4.A Changing of the Guard: Immune Checkpoint Inhibitors With and Without Chemotherapy as First Line Treatment for Metastatic Non-small Cell Lung Cancer

机译：改变警卫：免疫检查点抑制剂有无化疗作为转移性非小细胞肺癌的一线治疗
- 作者：Jose M. Pacheco;D. Ross Camidge;Robert C. Doebele;Erin Schenk
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- NSCLCcheckpoint inhibitorsclinical trialsKEYNOTECheckMateIMpower;
5.Hepatoma-Derived Growth Factor and DDX5 Promote Carcinogenesis and Progression of Endometrial Cancer by Activating β-Catenin

机译：肝癌衍生生长因子和DDX5通过激活β-连环蛋白促进子宫内膜癌的发生和发展。
- 作者：Chunhua Liu;Lijing Wang;Qingping Jiang;Junyi Zhang;Litong Zhu;Li Lin;Huiping Jiang;Dan Lin;Yanyi Xiao;Weiyi Fang;Suiqun Guo
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- ECHDGFDDX5β-cateninPI3K/AKT;
6.Molecular Targeted Therapy in the Treatment of Chordoma: A Systematic Review

机译：分子靶向疗法治疗脊索瘤：系统评价
- 作者：Tong Meng;Jiali Jin;Cong Jiang;Runzhi Huang;Huabin Yin;Dianwen Song;Liming Cheng
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- molecular targeted therapybone tumorchordomasystematic reviewimatiniberlotinib;
7.Computational Modeling of the Crosstalk Between Macrophage Polarization and Tumor Cell Plasticity in the Tumor Microenvironment

机译：肿瘤微环境中巨噬细胞极化与肿瘤细胞可塑性之间串扰的计算模型
- 作者：Xuefei Li;Mohit Kumar Jolly;Jason T. George;Kenneth J. Pienta;Herbert Levine
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- MET–mesenchymal-to-epithelial transitionEMT–epithelial-to-mesenchymal transitionM1-/M2-polarized macrophagesinteraction networkmulti-stability;
8.Effectiveness of Postoperative Radiotherapy on Atypical Meningioma Patients: A Population-Based Study

机译：非典型脑膜瘤患者术后放疗的有效性：一项基于人群的研究
- 作者：Qiang Zeng;Feina Shi;Zhige Guo
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- atypical meningiomaradiotherapyprognosissurgerygross-total resectionsubtotal resection;
9.Long Non-coding RNA CDKN2B Antisense RNA 1 Gene Contributes to Paclitaxel Resistance in Endometrial Carcinoma

机译：长非编码RNA CDKN2B反义RNA 1基因有助于子宫内膜癌的紫杉醇耐药性。
- 作者：Chao Shang;Cheng N. Ao;Chi C. Cheong;Lirong Meng
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- non-coding RNAendometrial carcinomaCDKN2B antisense RNA 1miR-125a-5pchemotherapypaclitaxel;
10.Merkel Cell Polyoma Viral Load and Intratumoral CD8+ Lymphocyte Infiltration Predict Overall Survival in Patients With Merkel Cell Carcinoma

机译：默克尔细胞多瘤病毒载量和肿瘤内CD8 +淋巴细胞浸润可预测默克尔细胞癌患者的总体生存率
- 作者：Jens von der Grün;Ria Winkelmann;Markus Meissner;Ulrike Wieland;Steffi Silling;Daniel Martin;Emmanouil Fokas;Claus R?del;Franz R?del;Panagiotis Balermpas
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- merkel cell carcinomapolyomavirus (MCPyV)CD8+ tumor infiltrating lymphocytesPD-L1radioimmunotherpay;
11.Biliary Neuroendocrine Neoplasms: Clinical Profiles, Management, and Analysis of Prognostic Factors

机译：胆道神经内分泌肿瘤：临床概况，管理和预后因素分析。
- 作者：Zhibo Zheng;Chuyan Chen;Binglu Li;Hongbo Liu;Liangrui Zhou;Hui Zhang;Chaoji Zheng;Xiaodong He;Wei Liu;Tao Hong;Yupei Zhao
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- neuroendocrine neoplasmgallbladderbiliary tractampullasurvival;
12.Overcoming Resistance to Natural Killer Cell Based Immunotherapies for Solid Tumors

机译：克服对实体肿瘤基于自然杀伤细胞的免疫疗法的耐药性
- 作者：Gaurav Nayyar;Yaya Chu;Mitchell S. Cairo
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- natural killer cellchimeric antigen receptorimmunotherapysolid tumorcytokinestumor microenvironmentcheckpoint inhibitorsbispecific antibody;
13.EBV Viral Loads in Diagnosis, Monitoring, and Response Assessment

机译：EBV病毒载量在诊断，监测和反应评估中的作用
- 作者：Hiroshi Kimura;Yok-Lam Kwong
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- EBV-DNAchronic active EBV infectionextranodal NK/T-cell lymphomanasal typepost-transplant lymphoproliferative disordersHodgkin lymphoma;
14.Nociceptin Receptor Is Overexpressed in Non-small Cell Lung Cancer and Predicts Poor Prognosis

机译：Nociceptin受体在非小细胞肺癌中过表达并预测不良预后
- 作者：Kaiyuan Wang;Yu Zheng;Yinli Yang;Jian Wang;Baihui Li;Feng Wei;Hongwei Zhao;Xiubao Ren
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- receptornociceptincarcinomanon-small-cell lungreceptorsopioidmorphinesurvival analysis;
15.Antibody-Drug Conjugates (ADC) Against Cancer Stem-Like Cells (CSC)—Is There Still Room for Optimism?

机译：抗癌干细胞（CSC）的抗体-药物结合物（ADC）—是否仍有乐观的余地？
- 作者：Fabrizio Marcucci;Carmelo Antonio Caserta;Elisabetta Romeo;Cristiano Rumio
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- cancer stem cellepithelial-mesenchymal transitionresistanceantibody-drug conjugaterestingproliferating;
16.Microbiome and Cancers, With Focus on Genitourinary Tumors

机译：微生物组和癌症，以泌尿生殖道肿瘤为重点
- 作者：Alessia Cimadamore;Matteo Santoni;Francesco Massari;Silvia Gasparrini;Liang Cheng;Antonio Lopez-Beltran;Rodolfo Montironi;Marina Scarpelli
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- microbiomerenal cell carcinomaimmunotherapyresistancePD-1 blockadeantibiotic therapyprostate cancer;
17.Lysosomal Pathways and Autophagy Distinctively Control Endothelial Cell Behavior to Affect Tumor Vasculature

机译：溶酶体途径和自噬显着控制内皮细胞行为以影响肿瘤血管。
- 作者：Marco B. Schaaf;Diede Houbaert;Odeta Me?e;San Kit To;Maarten Ganne;Hannelore Maes;Patrizia Agostinis
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- Autophagytumor endothelial cellsintercellular crosstalkVEGF/VEGFR-axisAngiopoietin1PDGFR-β;
18.Geographical Variations in Prostate Cancer Outcomes: A Systematic Review of International Evidence

机译：前列腺癌结果的地理差异：国际证据的系统评价
- 作者：Paramita Dasgupta;Peter D. Baade;Joanne F. Aitken;Nicholas Ralph;Suzanne Kathleen Chambers;Jeff Dunn
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- prostate cancerruralarea-disadvantagehealth disparitysystematic reviewgeographical variationscontinuum of care;
19.Role of Radiosurgery/Stereotactic Radiotherapy in Oligometastatic Disease: Brain Oligometastases

机译：放射外科/立体定向放射治疗在低位转移性疾病中的作用：脑低聚转移。
- 作者：Rosario Mazzola;Stefanie Corradini;Fabiana Gregucci;Vanessa Figlia;Alba Fiorentino;Filippo Alongi
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- oligometastasesradiosurgerystereotactic radiotherapybrain metastasesradiotherapy;
20.Current Murine Models and New Developments in H3K27M Diffuse Midline Gliomas

机译：H3K27M弥散中线胶质瘤的当前小鼠模型和新发展
- 作者：John P. Welby;Tatiana Kaptzan;Anton Wohl;Timothy E. Peterson;Aditya Raghunathan;Desmond A. Brown;Shiv K. Gupta;Liang Zhang;David J. Daniels
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- gliomaDIPGdiffuse intrinsic pontine gliomaH3K27Mxenograft;
21.EYA2 Correlates With Clinico-Pathological Features of Breast Cancer, Promotes Tumor Proliferation, and Predicts Poor Survival

机译：EYA2与乳腺癌的临床病理特征相关，促进肿瘤增殖，并预测生存不良
- 作者：Hanxiao Xu;Ying Jiao;Ming Yi;Weiheng Zhao;Kongming Wu
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- breast cancerEYA2tumor grademolecular subtypesproliferationepithelial-mesenchymal transitioncancer stem cellsprognosis;
22.Cancer-Induced Reprogramming of Host Glucose Metabolism: “Vicious Cycle” Supporting Cancer Progression

机译：癌症引起的宿主葡萄糖代谢的重编程：“恶性循环”支持癌症进展
- 作者：Polina Schwartsburd
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- cancer biologyglucoseinsulin resistancemetabolismpregnancystress;
23.IRF6 Is Directly Regulated by ZEB1 and ELF3, and Predicts a Favorable Prognosis in Gastric Cancer

机译：IRF6由ZEB1和ELF3直接调控，并预测胃癌的预后良好
- 作者：Dandan Li;Ping Cheng;Jingjie Wang;Xuemei Qiu;Xudong Zhang;Li Xu;Ying Liu;Shanshan Qin
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- IRF6ELF3ZEB1transcriptional regulationgastric cancer;
24.Pretreatment Level of Red Cell Distribution Width as a Prognostic Indicator for Survival in a Large Cohort Study of Male Laryngeal Squamous Carcinoma

机译：红细胞分布宽度的预处理水平作为男性喉鳞癌大队列研究生存的预后指标
- 作者：Chi-Yao Hsueh;Hui-Ching Lau;Shengjie Li;Lei Tao;Ming Zhang;Hongli Gong;Liang Zhou
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- laryngeal squamous cell cancermalered cell distribution widthprognosisbiomarker;
25.Organoids Increase the Predictive Value of in vitro Cancer Chemoprevention Studies for in vivo Outcome

机译：有机物提高体外癌症化学预防研究对体内结果的预测价值。
- 作者：Rose N. Njoroge;Rajita J. Vatapalli;Sarki A. Abdulkadir
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- organoidsvitamin Eseleniumselectprostate canceranoikismetabolismextracellular matrix (ECM);
26.Targeting JUN, CEBPB, and HDAC3: A Novel Strategy to Overcome Drug Resistance in Hypoxic Glioblastoma

机译：针对JUN，CEBPB和HDAC3：克服缺氧性胶质母细胞瘤耐药性的新策略
- 作者：Yixing Gao;Bao Liu;Lan Feng;Binda Sun;Shu He;Yidong Yang;Gang Wu;Guoji E;Chang Liu;Yuqi Gao;Erlong Zhang;Bo Zhu
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- glioblastomahypoxiadrug resistanceJUNCEBPBHDAC3;
27.Disease Control With Delayed Salvage Radiotherapy for Macroscopic Local Recurrence Following Radical Prostatectomy

机译：前列腺癌根治术后延迟救治放疗对宏观局部复发的疾病控制
- 作者：Mohamed Shelan;Seline Odermatt;Beat Bojaxhiu;Daniel P. Nguyen;George N. Thalmann;Daniel M. Aebersold;Alan Dal Pra
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- prostate cancersalvage radiationlocal recurrencemacroscopic recurrencepostoperative radiotherapy;
28.Survivin in Insulin-Like Growth Factor-Induced Resistance to Lapatinib in Head and Neck Squamous Carcinoma Cells

机译：Survivin在胰岛素样生长因子诱导的头颈部鳞状细胞癌细胞中对拉帕替尼的抗性
- 作者：Christine E. Lehman;Rolando E. Mendez;Michael I. Dougherty;Amir Allak;Oluwayemisi L. Adejumo;Linnea E. Taniguchi;Ashraf Khalil;Daniel G. Gioeli;Mark J. Jameson
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- survivinIGF1RlapatinibEGFRHNSCCresistance;
29.Endometrial Cytology as a Method to Improve the Accuracy of Diagnosis of Endometrial Cancer: Case Report and Meta-Analysis

机译：子宫内膜细胞学作为提高子宫内膜癌诊断准确性的方法：病例报告和荟萃分析
- 作者：Qing Wang;Qi Wang;Lanbo Zhao;Lu Han;Chao Sun;Sijia Ma;Huilian Hou;Qing Song;Qiling Li
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- cytologyhistologyendometrial cancerdiagnosisatypical hyperplasia;
30.Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations

机译： Gprc5a 缺陷的鼠肺腺癌伴体细胞 Kras 突变的干细胞祖细胞的全基因组和表型评估
- 作者：Reem Daouk;Maya Hassane;Hisham F. Bahmad;Ansam Sinjab;Junya Fujimoto;Wassim Abou-Kheir;Humam Kadara
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- lung adenocarcinomaKrasstem cell progenitorsGprc5alung cancer pathogenesis;
31.Turning the Tide Against Regulatory T Cells

机译：逆转调节性T细胞
- 作者：SeongJun Han;Aras Toker;Zhe Qi Liu;Pamela S. Ohashi
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- immune regulationTreg cellsT cellstumor immunityimmune therapy;
32.Adjunctive Use of Circulating Tumor DNA Testing in Detecting Pancreas Cancer Recurrence

机译：循环肿瘤DNA检测在胰腺癌复发检测中的辅助应用
- 作者：Aixa E. Soyano;Candice Baldeo;Pashtoon M. Kasi
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- pancreas cancercirculating tumor DNA (ctDNA)circulating tumor cells (CTC)liquid biopsyrelapse/recurrence;
33.A Mediterranean Diet Mix Has Chemopreventive Effects in a Murine Model of Colorectal Cancer Modulating Apoptosis and the Gut Microbiota

机译：地中海饮食混合物在大肠癌调节细胞凋亡和肠道菌群的小鼠模型中具有化学预防作用。
- 作者：Giulia Piazzi;Anna Prossomariti;Maurizio Baldassarre;Claudio Montagna;Paola Vitaglione;Vincenzo Fogliano;Elena Biagi;Marco Candela;Patrizia Brigidi;Tiziana Balbi;Alessandra Munarini;Andrea Belluzzi;Milena Pariali;Franco Bazzoli;Luigi Ricciardiello
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- colorectal cancerchemopreventionmicrobiotaMediterranean dietomega-3;
34.Synthesis and Anticancer Activity Evaluation of Novel Phenanthridine Derivatives

机译：新型菲啶衍生物的合成及抗癌活性评价
- 作者：Minghui Wan;Lei Zhang;Yiming Chen;Qiang Li;Wenli Fan;Qingxia Xue;Fang Yan;Weiguo Song
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- phenanthridineanticancertopoisomeraseapoptosiscell cycle arrest;
35.Chasing Zero Harm in Radiation Oncology: Using Pre-treatment Peer Review

机译：在放射肿瘤学中追求零伤害：使用治疗前同行评审
- 作者：Srinivasan Vijayakumar;William Neil Duggar;Satya Packianathan;Bart Morris;Chunli Claus Yang
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- pre-treatment peer reviewchasing zero harmquality assurancesafety in radiation treatmentradiation oncology;
36.BAG3 Suppresses Loading of Ago2 to IL6 mRNA in Pancreatic Ductal Adenocarcinoma

机译：BAG3抑制胰腺导管腺癌中Ago2到IL6 mRNA的负载。
- 作者：Chao Li;Ming-Xin An;Jing-Yi Jiang;Han-Bing Yao;Si Li;Jing Yan;Xin-Yu Li;Hua-Qin Wang
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- BAG3IL6Ago2pancreatic cancerfibrosis;
37.Efficacy and Tolerance of Post-operative Hypo-Fractionated Stereotactic Radiotherapy in a Large Series of Patients With Brain Metastases

机译：大范围脑转移患者术后低位立体定向放射疗法的疗效和耐受性
- 作者：Geoffrey Martinage;Julien Geffrelot;Dinu Stefan;Emilie Bogart;Erwan Rault;Nicolas Reyns;Evelyne Emery;Samira Makhloufi-Martinage;Raphaelle Mouttet-Audouard;Laurent Basson;Xavier Mirabel;Eric Lartigau;David Pasquier
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- radiotherapyhypofractionated stereotactic radiation therapybrain metastasissurgeryCyberknife;
38.Perspectives of Induction With Chemo and/or Immune Check Point Inhibition in Head and Neck Organ Preservation Treatment

机译：头颈部器官保存治疗中化学和/或免疫检查点抑制诱导的观点
- 作者：Susanne Wiegand;Gunnar Wichmann;Andreas Dietz
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- PD-1PD-L1neoadjuvantchemotherapyimmunotherapy;
39.Dosimetric Performance and Planning/Delivery Efficiency of a Dual-Layer Stacked and Staggered MLC on Treating Multiple Small Targets: A Planning Study Based on Single-Isocenter Multi-Target Stereotactic Radiosurgery (SRS) to Brain Metastases

机译：多层堆叠交错MLC治疗多个小目标的剂量学性能和计划/交付效率：一项基于单等中心多目标立体定向放射外科（SRS）进行脑转移的计划研究
- 作者：Taoran Li;Peyton Irmen;Haisong Liu;Wenyin Shi;Michelle Alonso-Basanta;Wei Zou;Boon-Keng Kevin Teo;James M. Metz;Lei Dong
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- halcyonstereotactic radiosurgery (SRS)multi-leaf collimator (MLC)single-isocenter multi-targettruebeambrain metastase;
40.Differential Oxygenation in Tumor Microenvironment Modulates Macrophage and Cancer Cell Crosstalk: Novel Experimental Setting and Proof of Concept

机译：肿瘤微环境中的差异氧合调节巨噬细胞和癌细胞串扰：新颖的实验设置和概念证明。
- 作者：Noelia Campillo;Bryan Falcones;Jordi Otero;Roser Colina;David Gozal;Daniel Navajas;Ramon Farré;Isaac Almendros
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- hypoxia gradientmacrophage motilitymodels of host-tumor interactionsnovel assay technologytumor progression;
41.Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL

机译：组蛋白修饰驱动Notch3在T-ALL中的表达/活性和生长
- 作者：Luca Tottone;Nadezda Zhdanovskaya;álvaro Carmona Pesta?a;Michele Zampieri;Fabrizio Simeoni;Sara Lazzari;Valeria Ruocco;Maria Pelullo;Paola Caiafa;Maria Pia Felli;Saula Checquolo;Diana Bellavia;Claudio Talora;Isabella Screpanti;Rocco Palermo
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- Notch signalingT-cell lymphoblastic leukemiaepigeneticsJMJD3p300gene regulationGSKJ4A-485;
42.Radiopharmaceuticals for Relapsed or Refractory Ovarian Cancers

机译：复发性或难治性卵巢癌的放射性药物
- 作者：Charles A. Kunos;Jacek Capala;Shanda Finnigan;Gary L. Smith;Susan Percy Ivy
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- radiopharmaceuticalradiationradionuclidesnuclear medicineovarian cancer;
43.Non-coding and Coding Transcriptional Profiles Are Significantly Altered in Pediatric Retinoblastoma Tumors

机译：小儿视网膜母细胞瘤肿瘤中的非编码和编码转录谱显着改变。
- 作者：Swetha Rajasekaran;Lakshmi Dhevi Nagarajha Selvan;Kathleen Dotts;Ranjith Kumar;Pukhraj Rishi;Vikas Khetan;Madhoolika Bisht;Karthikeyan Sivaraman;Subrmanian Krishnakumar;Debashis Sahoo;Moray J. Campbell;Sailaja V. Elchuri;Wayne O. Miles
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- retinoblastomaLNC-RNAsRNA-sequencingLNC targetingDRAIC;
44.Diverse Mechanisms of BRAF Inhibitor Resistance in Melanoma Identified in Clinical and Preclinical Studies

机译：临床和临床前研究确定了BRAF抑制剂抵抗黑色素瘤的多种机制。
- 作者：Stephen A. Luebker;Scott A. Koepsell
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- melanomaBRAF inhibitorvemurafenibdabrafenibcell linedrug resistancemetabolisminvasion;
45.Apixaban for Primary Prevention of Venous Thromboembolism in Patients With Multiple Myeloma Receiving Immunomodulatory Therapy

机译：阿哌沙班用于接受免疫调节治疗的多发性骨髓瘤患者的静脉血栓栓塞的一级预防
- 作者：Robert Frank Cornell;Samuel Z. Goldhaber;Brian G. Engelhardt;Javid Moslehi;Madan Jagasia;Daryl Patton;Shelton Harrell;Robert Hall;Houston Wyatt;Greg Piazza
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- Apixaban (Eliquis?)myelomaanticoagulation (AC)immunomodualtorsvenous thomboembolism;
46.Tumor Tissue Explant Culture of Patient-Derived Xenograft as Potential Prioritization Tool for Targeted Therapy

机译：患者来源异种移植的肿瘤组织外植体培养作为靶向治疗的潜在优先手段
- 作者：Susmita Ghosh;Manu Prasad;Kiran Kundu;Limor Cohen;Ksenia M. Yegodayev;Jonathan Zorea;Ben-Zion Joshua;Batel Lasry;Orr Dimitstein;Anat Bahat-Dinur;Aviram Mizrachi;Vladimir Lazar;Moshe Elkabets;Angel Porgador
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- head and neck cancerpatient derived xenograftsex vivoexplant culturetargeted therapy;
47.21-Gene Recurrence Score Assay and Outcomes of Adjuvant Radiotherapy in Elderly Women With Early-Stage Breast Cancer After Breast-Conserving Surgery

机译：乳腺癌保乳术后老年妇女21基因复发评分测定及辅助放疗结果
- 作者：San-Gang Wu;Wen-Wen Zhang;Jun Wang;Yong Dong;Jia-Yuan Sun;Yong-Xiong Chen;Zhen-Yu He
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- breast cancerelderly21-gene recurrence scoreradiotherapybreast-conserving surgery;
48.Diagnostic Significance of Serum IgG Galactosylation in CA19-9-Negative Pancreatic Carcinoma Patients

机译：血清IgG半乳糖基化对CA19-9阴性胰腺癌患者的诊断意义。
- 作者：Ailing Zhong;Ruihuan Qin;Wenjun Qin;Jing Han;Yong Gu;Lei Zhou;Hongqin Zhang;Shifang Ren;Renquan Lu;Lin Guo;Jianxin Gu
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- pancreatic carcinomaIgGgalactosylationdiagnostic biomarkerCA19-9;
49.Glioblastoma Stem- Like Cells, Metabolic Strategy to Kill a Challenging Target

机译：胶质母细胞瘤干细胞（ Like ）细胞的代谢策略可杀死具有挑战性的靶标
- 作者：Delphine Garnier;Ophélie Renoult;Marie-Clotilde Alves-Guerra;Fran?ois Paris;Claire Pecqueur
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- Glioblastomacancer stem cellscancer metabolismtumor microenvironmentcancer heterogeneitycancer plasticity;
50.Seeking for Correlative Genes and Signaling Pathways With Bone Metastasis From Breast Cancer by Integrated Analysis

机译：综合分析寻找乳腺癌骨转移的相关基因和信号通路
- 作者：Yu Zhang;Wendan He;Sen Zhang
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- breast cancerbone metastasisdiagnosemRNA expression profileprotein-protein interactiontranscription factors-target gene;
51.Endothelial Cell-Derived TGF-β Promotes Epithelial-Mesenchymal Transition via CD133 in HBx-Infected Hepatoma Cells

机译：内皮细胞衍生的TGF-β通过HBx感染的肝癌细胞通过CD133促进上皮-间质转化
- 作者：Preety Rawal;Hamda Siddiqui;Mohsin Hassan;Manish Chandra Choudhary;Dinesh M. Tripathi;Vikrant Nain;Nirupama Trehanpati;Savneet Kaur
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- epithelial to mesenchymal transition (EMT)endothelial cellshepatocellular carcinoma (HCC)hepatitis B virus X protein (HBx)transforming growth factor Beta (TGF-β)tumor microenvironment;
52.TET2 Function in Hematopoietic Malignancies, Immune Regulation, and DNA Repair

机译：TET2在造血系统恶性肿瘤，免疫调节和DNA修复中的功能
- 作者：Yimei Feng;Xiaoping Li;Kaniel Cassady;Zhongmin Zou;Xi Zhang
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- TET2SIRT1DNA demethylationDNA repairDNA stability;
53.Association Between Physical Activity and Lower Risk of Lung Cancer: A Meta-Analysis of Cohort Studies

机译：体力活动与肺癌风险降低之间的关联：一项队列研究的荟萃分析
- 作者：Yang Liu;Yue Li;Yun-Peng Bai;Xiao-Xi Fan
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- physical activitylung cancersmokingcohort studymeta-analysis;
54.MPT0G413, A Novel HDAC6-Selective Inhibitor, and Bortezomib Synergistically Exert Anti-tumor Activity in Multiple Myeloma Cells

机译：MPT0G413，一种新型的HDAC6选择性抑制剂和Bortezomib在多发性骨髓瘤细胞中协同发挥抗肿瘤活性
- 作者：Fang-I Huang;Yi-Wen Wu;Ting-Yi Sung;Jing-Ping Liou;Mei-Hsiang Lin;Shiow-Lin Pan;Chia-Ron Yang
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- multiple myeloma cellshistone deacetylase 6bortezomibcombination therapybone marrow stromal cellssynergistic effect;
55.Gene Therapy Leaves a Vicious Cycle

机译：基因治疗留下了恶性循环
- 作者：Reena Goswami;Gayatri Subramanian;Liliya Silayeva;Isabelle Newkirk;Deborah Doctor;Karan Chawla;Saurabh Chattopadhyay;Dhyan Chandra;Nageswararao Chilukuri;Venkaiah Betapudi
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- gene therapyviral vectorsmodern medicinesdiseases and disordersclinical trials;
56.Prolonged Sitting, Its Combination With Physical Inactivity and Incidence of Lung Cancer: Prospective Data From the HUNT Study

机译：长时间坐着，其与缺乏运动能力和肺癌发病率的结合：来自HUNT研究的前瞻性数据
- 作者：Lin Jiang;Yi-Qian Sun;Ben Michael Brumpton;Arnulf Langhammer;Yue Chen;Tom I. L. Nilsen;Xiao-Mei Mai
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- prolonged sittingphysical inactivitylung cancer riskprospective cohortHUNT study;
57.Temozolomide Induced Hypermutation in Glioma: Evolutionary Mechanisms and Therapeutic Opportunities

机译：替莫唑胺在胶质瘤中引起的高突变：进化机制和治疗机会。
- 作者：Paul Daniel;Siham Sabri;Ahmad Chaddad;Brian Meehan;Bertrand Jean-Claude;Janusz Rak;Bassam S. Abdulkarim
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- gliomarecurrenceMGMThypermutationtemozolomide;
58.The Effect of Hexavalent Chromium on the Incidence and Mortality of Human Cancers: A Meta-Analysis Based on Published Epidemiological Cohort Studies

机译：六价铬对人类癌症发病率和死亡率的影响：基于已发表的流行病学队列研究的荟萃分析
- 作者：Yujiao Deng;Meng Wang;Tian Tian;Shuai Lin;Peng Xu;Linghui Zhou;Cong Dai;Qian Hao;Ying Wu;Zhen Zhai;Yue Zhu;Guihua Zhuang;Zhijun Dai
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- hexavalent chromiumcancermortalityincidencemeta-analysis;
59.Translating Human Cancer Sequences Into Personalized Porcine Cancer Models

机译：将人类癌症序列转化为个性化的猪癌症模型
- 作者：Chunlong Xu;Sen Wu;Lawrence B. Schook;Kyle M. Schachtschneider
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- personalized cancer modelsexome sequencinggene editingtranslational researchclinical needs;
60.Everolimus in Anaplastic Thyroid Cancer: A Case Series

机译：依维莫司在间变性甲状腺癌中的病例系列
- 作者：Ethan J. Harris;Glenn J. Hanna;Nicole Chau;Guilherme Rabinowits;Robert Haddad;Danielle N. Margalit;Jonathan Schoenfeld;Roy B. Tishler;Justine A. Barletta;Matthew Nehs;Pasi Janne;Julian Huang;Phillip Groden;Alec Kacew;Jochen Lorch
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- anaplastic thyroid cancer (ATC)precision medicinemTOR inhibition in head and neck cancerexceptional responderPI3K mTOR;
61.CAR-Based Approaches to Cutaneous T-Cell Lymphoma

机译：基于CAR的皮肤T细胞淋巴瘤治疗方法
- 作者：Irene Scarfò;Matthew J. Frigault;Marcela V. Maus
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- T cell lymphomas/leukemiasCAR T cellsadoptive cell therapyimmunotherapycutaneous;
62.Impacts of Surgery on Symptom Burden and Quality of Life in Pituitary Tumor Patients in the Subacute Post-operative Period

机译：亚急性手术后手术对垂体瘤患者症状负担和生活质量的影响
- 作者：Mark R. Waddle;Mollie D. Oudenhoven;Casey V. Farin;Allison M. Deal;Riane Hoffman;Hojin Yang;Jennifer Peterson;Terri S. Armstrong;Matthew G. Ewend;Jing Wu
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- pituitaryadenomasurgeryQOLsubacutepost-operative;
63.Rescue of Immunotherapy-Refractory Metastatic Merkel Cell Carcinoma With Conventionally Fractionated Radiotherapy and Concurrent Pembrolizumab

机译：常规分次放疗和同时进行的派姆单抗的免疫治疗难治性转移性默克尔细胞癌的抢救
- 作者：Brooke C. Bloom;Alexander Augustyn;Todd A. Pezzi;Hari Menon;Lauren L. Mayo;Shalin J. Shah;David L. Schwartz;Steven J. Chmura;Faye M. Johnson;James W. Welsh;Stephen G. Chun
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- Merkel cell carcinomaradiationabscopalPD-1PD-L1immunotherapycheckpoint;
64.Human Ovarian Cancer Tumor Formation in Severe Combined Immunodeficient (SCID) Pigs

机译：严重联合免疫缺陷（SCID）猪的人卵巢癌肿瘤形成
- 作者：Adeline N. Boettcher;Matti Kiupel;Malavika K. Adur;Emiliano Cocco;Alessandro D. Santin;Stefania Bellone;Sara E. Charley;Barbara Blanco-Fernandez;John I. Risinger;Jason W. Ross;Christopher K. Tuggle;Erik M. Shapiro
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- ovarian cancersevere combined immunodeficientswinepreclinical animal modelClaudin;
65.Helicobacter pylori Eradication for Metachronous Gastric Cancer: An Unsuitable Methodology Impeding Broader Clinical Usage

机译：根治性胃癌的幽门螺杆菌：不合适的方法论阻碍了更广泛的临床应用
- 作者：Alexios-Fotios A. Mentis;Efthimios Dardiotis
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- Helicobacter pylorigastric cancerinfectionantibiotic therapyclinical trialpathogen;
66.ACE Insertion/Deletion Polymorphism (rs4646994) Is Associated With the Increased Risk of Multiple Myeloma

机译： ACE 插入/缺失多态性（rs4646994）与多发性骨髓瘤的风险增加相关
- 作者：Szymon Zmorzynski;Aneta Szudy-Szczyrek;Sylwia Popek-Marciniec;Iwona Korszen-Pilecka;Magdalena Wojcierowska-Litwin;Ma?gorzata Luterek;Sylwia Chocholska;Wojciech Styk;Grazyna Swiderska-Ko?acz;Joanna Januszewska;Michal Mielnik;Marek Hus;Agata A. Filip
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- ACEgeneI/D polymorphismplasma cell myelomabortezomibrs4646994;
67.Targeting uPAR by CRISPR/Cas9 System Attenuates Cancer Malignancy and Multidrug Resistance

机译：通过CRISPR / Cas9系统靶向uPAR可减轻癌症恶性和多药耐药性
- 作者：Kun Wang;Zi-Hao Xing;Qi-Wei Jiang;Yang Yang;Jia-Rong Huang;Meng-Ling Yuan;Meng-Ning Wei;Yao Li;Sheng-Te Wang;Kun Liu;Zhi Shi
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- canceruPARCRISPR/Cas9malignancydrug resistance;
68.Immunotherapeutic Targeting of GPC3 in Pediatric Solid Embryonal Tumors

机译：GPC3在小儿实体胚胎肿瘤中的免疫治疗靶向。
- 作者：Michael V. Ortiz;Stephen S. Roberts;Julia Glade Bender;Neerav Shukla;Leonard H. Wexler
- 期刊名称：《Frontiers in Oncology》 | 2019年第1期
- glypican 3hepatoblastoma (HB)germ cell tumors (GCT)Wilms tumor (WT)rhabdoid tumorrhabdomyosarcomaneuroblastomaimmunotherapy;

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