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Interdisciplinary Sciences: Computational Life Sciences

Interdisciplinary Sciences: Computational Life Sciences

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中文名称：交叉学科:计算生命科学

ISSN：1913-2751
出版周期：Quarterly

发文量：276

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1.Clustering and Candidate Motif Detection in Exosomal miRNAs by Application of Machine Learning Algorithms

机译：机器学习算法应用胚胎miRNA中的聚类和候选主题检测
- 作者：Gaur Pallavi;Chaturvedi Anoop
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Motif;
- Machine learning algorithms;
- Exosomal miRNAs;
- k-Means clustering;
2.PD-L1 Expression and Its Regulation in Lung Adenocarcinoma with ALK Translocation

机译：PD-L1表达及其在肺腺癌中的表达及其对alk易位的调节
- 作者：Ma Li;Lv Jialin;Dong Yujie;Zhang Xinyong;Li Xi;Zhang Hui;Nong Jingying;Zhang Quan;Qin Na;Yang Xinjie;Wang Jinghui;Zhang Shucai
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- NSCLC;
- ALK;
- PD-L1;
- Mechanism;
3.Structural Probing, Screening and Structure-Based Drug Repositioning Insights into the Identification of Potential Cox-2 Inhibitors from Selective Coxibs

机译：从选择性Coxibs识别潜在Cox-2抑制剂的结构探测，筛选和结构的药物重新定位
- 作者：Bommu Uma Devi;Konidala Kranthi Kumar;Pamanji Rishika;Yeguvapalli Suneetha
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- COX-2;
- Optimized modeling;
- Celebrex;
- Comparative docking;
- Molecular dynamics and GBIS simulations;
- ADME-Tox;
4.Network Analysis of MPO and Other Relevant Proteins Involved in Diabetic Foot Ulcer and Other Diabetic Complications

机译：糖尿病足溃疡和其他糖尿病并发症的MPO和其他相关蛋白质的网络分析
- 作者：Saumya Mathew;Subin E. K.;Suchithra T. V.
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Myeloperoxidase;
- Foot ulcer;
- Type 1 diabetes;
- Type 2 diabetes;
- Cytoscape;
5.Design of 2-Nitroimidazooxazine Derivatives as Deazaflavin-Dependent Nitroreductase (Ddn) Activators as Anti-Mycobacterial Agents Based on 3D QSAR, HQSAR, and Docking Study with In Silico Prediction of Activity and Toxicity

机译：将2-硝基咪唑嗪衍生物作为Deazaflavin依赖性硝化酶（DDN）活化剂为基于3D QSAR，HQSAR和对接研究的抗分枝杆菌剂，以及在硅的活性和毒性预测的基础上
- 作者：Gupta Nirzari;Vyas Vivek K.;Patel Bhumika D.;Ghate Manjunath
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Mycobacterium tuberculosis;
- Deazaflavin-dependent nitroreductase (Ddn);
- 3D QSAR;
- HQSAR;
- Docking;
- In silico ADMET;
6.An Overview of Scoring Functions Used for Protein-Ligand Interactions in Molecular Docking

机译：用于分子对接中蛋白质 - 配体相互作用的评分功能概述
- 作者：Li Jin;Fu Ailing;Zhang Le
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Molecular docking;
- Scoring function;
- Ligand pose;
- Binding affinity;
- Protein-ligand interaction;
7.Accelerated Versus Conventional Corneal Collagen Cross-Linking in the Treatment of Keratoconus: A Meta-analysis and Review of the Literature

机译：加速与常规角膜胶原蛋白交联在Keratoconus治疗中：文献的荟萃分析和审查
- 作者：Jiang Yang;Yang Shan;Li Ying;Cui Ge;Lu Thomas Chengxuan
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
8.Nivolumab-induced Thyroid Dysfunctions in Patients with Previously Treated Non-small Cell Lung Cancer

机译：患有先前治疗的非小细胞肺癌的患者的Nivolumab诱导的甲状腺功能障碍
- 作者：Zhang Xinyong;Wu Yuhua;Lv Jialin;Li Xi;Ma Li;Nong Jingying;Zhang Hui;Qin Na;Zhang Quan;Shi Guangli;Yang Xinjie;Wang Jinghui;Zhang Shucai
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Non-small cell lung cancer;
- Anti-PD-1 antibody;
- Nivolumab;
- Thyroid;
- Dysfunction;
- Immunotherapy;
9.Quantitative and Visual Characteristics of Primary Central Nervous System Lymphoma on F-18-FDG-PET

机译：F-18-FDG-PET对原发性中枢神经系统淋巴瘤的定量和视觉特征
- 作者：Liu Delin;Kong Ziren;Wang Yuekun;Chen Wenlin;Wang Yaning;Chen Wanqi;Liu Lei;Dang Yonghong;Ma Wenbin;Wang Yu;Cheng Xin
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- F-18-FDG;
- Positron emission tomography;
- Lymphoma;
- Visual characteristic;
10.In Silico Drug Design of Thiolactomycin Derivatives Against Mtb-KasA Enzyme to Inhibit Multidrug Resistance of Mycobacterium tuberculosis

机译：在对MTB-KASA酶的硫酰基霉素衍生物的硅药物设计中，抑制结核分枝杆菌的多药抗性
- 作者：Durairaj D. Ruban;Shanmughavel P.
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- KasA;
- Thiolactomycin;
- Molecular dynamics simulation;
- Multidrug resistance;
- In silico drug design;
- Tuberculosis;
11.MYOD and HAND transcription factors have conserved recognition sites in mTOR promoter: insights from in silico analysis

机译：Myod和Hand转录因子在MTOR启动子中具有保守的识别位点：Silico分析中的见解
- 作者：Awasthi Ankita;Nain Vikrant;Puria Rekha
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Phylogentic foot printing;
- Transcription factor binding sites;
- Gene regulation;
- PI3K;
- AKT pathway;
- Sequence conservation;
- Evolution;
- DNA protein interaction;
12.Protection of Primary Dopaminergic Midbrain Neurons Through Impact of Small Molecules Using Virtual Screening of GPR139 Supported by Molecular Dynamic Simulation and Systems Biology

机译：通过使用分子动态模拟和系统生物学支持GPR139的虚拟筛选，通过小分子的影响保护原发性多巴胺能中脑神经元的保护
- 作者：Kaushik Aman Chandra;Gautam Deeksha;Nangraj Asma Sindhoo;Wei Dong-Qing;Sahi Shakti
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- GPCR;
- GPR139;
- 7TM;
- Primary dopaminergic midbrain neurons;
- MD simulation;
13.Population Scale Retrospective Analysis Reveals Potential Risk of Cholestasis in Pregnant Women Taking Omeprazole, Lansoprazole, and Amoxicillin

机译：人口规模回顾性分析揭示了在奥美拉唑，兰辛拉唑和阿莫西林服用孕妇胆囊中胆汁淤积的潜在风险
- 作者：Zhang Yonghong;Shi Da;Abagyan Ruben;Dai Weina;Dong Mingyang
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Adverse effect;
- Drug-induced cholestasis;
- Intrahepatic cholestasis of pregnancy;
- Odds ratio;
14.Detecting Methylomic Biomarkers of Pediatric Autism in the Peripheral Blood Leukocytes

机译：在外周血白细胞中检测儿科自闭症的甲基组合生物标志物
- 作者：Feng Xin;Hao Xubing;Xin Ruihao;Gao Xiaoqian;Liu Minge;Li Fei;Wang Yubo;Shi Ruoyao;Zhao Shishun;Zhou Fengfeng
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Feature selection;
- Methylomic biomarkers;
- Autism;
15.Survey on Monitoring and Quality Controlling of the Mobile Biosignal Delivery

机译：移动生物交付监测与质量控制调查
- 作者：Pawar Pravin A.;Edla Damodar R.;Edoh Thierry;Shinde Vijay;van Beijnum Bert-Jan
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
16.Computational Study of HCV p7 Channel: Insight into a New Strategy for HCV Inhibitor Design

机译：HCV P7频道的计算研究：洞察HCV抑制剂设计的新策略
- 作者：Ying Beili;Pang Shichao;Yang Junchen;Zhong Yang;Wang Jingfang
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Hepatitis C virus;
- P7 channel;
- Structure-based drug design;
- Molecular modeling;
17.Correlation Between PD-L1 Expression and Clinicopathologic Features in 404 Patients with Lung Adenocarcinoma

机译：404例肺腺癌患者PD-L1表达与临床病理学特征的相关性
- 作者：Song Peng;Wu Shafei;Zhang Li;Zeng Xuan;Wang Jinghui
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- PD-L1;
- Expression;
- Lung adenocarcinoma;
- EGFR;
- ALK;
18.Construction of Transcriptional Regulatory Network of Alzheimer's Disease Based on PANDA Algorithm

机译：基于熊猫算法的阿尔茨海默病转录监管网络建设
- 作者：Ding Jieyuan;Kong Wei;Mou Xiaoyang;Wang Shuaiqun
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Alzheimer's disease;
- Regulatory network;
- Multi-data fusion;
- Regulatory mechanism;
19.Identification of Lead Molecules in Garcinia mangostana L. Against Pancreatic Cholesterol Esterase Activity: An In Silico Approach

机译：鉴定大肠杆菌癌铅分子L.抗胰胆固醇酯酶活性：硅胆固醇酶活性
- 作者：Varghese George Kadakasseril;Abraham Rini;Chandran Nisha N.;Habtemariam Solomon
- 期刊名称：《Interdisciplinary Sciences: Computational Life Sciences》 | 2019年第2期
- Garcinia mangostana;
- Cholesterol esterase;
- AutoDock;
- GOLD;
- Epicatechin;
- Euxanthone;
- Tetrahydroxy-xanthone;

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