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Molecular diversity

中文名称：分子多样性

ISSN：1381-1991
出版周期：2.071

发文量：159

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1.On the information expressed in enzyme primary structure: Lessons from Ribonuclease A

机译：关于酶一级结构表达的信息：核糖核酸酶A的教训
- 作者：Graham D.J.;Greminger J.L.
- 期刊名称：《Molecular diversity》 | 2010年第4期
- Brownian computation;
- Enzymes;
- Peptides;
- Primary structure;
- Proteins;
- Shannon information;
2.A new one-pot three-component synthesis of 2,4-diamino-5H-chromeno[2,3-b]pyridine-3-carbonitrilederivatives

机译：一种新的一锅三组分合成2,4-二氨基-5H-chromeno [2,3-b]吡啶-3-碳腈衍生物
- 作者：Ahmad Shaabani;Fatemeh Hajishaabanha;Hamid Mofakham;Ali Maleki
- 期刊名称：《Molecular diversity》 | 2010年第1期
- Chromeno2;
- 3-bpyridine;
- 2-Amino-1;
- 1;
- 3-tricyanopropene;
- Multicomponent coupling reaction;
- One-pot reaction;
- Catalyst-free reaction;
3.A computational study on cannabinoid receptors and potentbioactive cannabinoid ligands: homology modeling, docking,de novo drug design and molecular dynamics analysis

机译：大麻素受体和有效的生物活性大麻素配体的计算研究：同源性建模，对接，从头药物设计和分子动力学分析
- 作者：Serdar Durdagi;Manthos G. Papadopoulos;Panagiotis G. Zoumpoulakis;Catherine Koukoulitsa;Thomas Mavromoustakos
- 期刊名称：《Molecular diversity》 | 2010年第2期
- AMG3;
- Cannabinoids;
- Conformational analysis;
- 3D QSAR;
- Homology modeling;
- CB 1 and CB2 receptors;
4.Microwave-assisted synthesis using ionic liquids

机译：使用离子液体的微波辅助合成
- 作者：Rafael Martinez-Palou
- 期刊名称：《Molecular diversity》 | 2010年第1期
- Ionic liquids;
- Microwave;
- Organic synthesis;
- Polymer synthesis;
- Materials synthesis;
5.A combined LS-SVM & MLR QSAR workflow for predictingthe inhibition of CXCR3 receptor by quinazolinone analogs

机译：结合LS-SVM和MLR QSAR工作流程来预测喹唑啉酮类似物对CXCR3受体的抑制
- 作者：Antreas Afantitis;Georgia Melagraki;Haralambos Sarimveis;Panayiotis A. Koutentis;Olga Igglessi-Markopoulou;George Kollias
- 期刊名称：《Molecular diversity》 | 2010年第2期
- QSAR CXCR3;
- Molecular modelling;
- In silico predictions;
6.Multicomponent synthesis of dihydrobenzoxazepinones, bearing four diversity points, as potential α-helix mimics

机译：多组分合成具有四个多样性点的二氢苯并恶嗪酮类化合物，作为潜在的α-螺旋模拟物
- 作者：Banfi L.;Basso A.;Cerulli V.;Guanti G.;Lecinska P.;Monfardini I.;Riva R.
- 期刊名称：《Molecular diversity》 | 2010年第3期
- Alpha-helix mimics;
- Mitsunobu reaction;
- Multicomponent reactions;
- Ugi reaction;
7.Design of chemical libraries with potentially bioactive moleculesapplying a maximum common substructure concept

机译：具有最大潜在子结构概念的具有潜在生物活性分子的化学文库设计
- 作者：Michael Lisurek;Bernd Rupp;Jorg Wichard;Martin Neuenschwander;Jens Peter von Kries;Ronald Frank;Jorg Rademann;Ronald Kuhne
- 期刊名称：《Molecular diversity》 | 2010年第2期
- Bio informatics;
- Drug design;
- High throughput;
- screening Library design;
- Molecular diversity;
8.Diastereoselective synthesis of fused [1,3]oxazines from ethylpyruvate, activated acetylenes and N-heterocycles

机译：由丙酮酸乙酯，活化乙炔和N-杂环化合物非对映选择性合成稠合的[1,3]恶嗪
- 作者：Issa Yavari;Anvar Mirzaei;Zinatosadat Hossaini;Sanaz Souri
- 期刊名称：《Molecular diversity》 | 2010年第2期
- Ethyl pyruvate;
- Activated acetylenes;
- Quinoline;
- Isoquinoline;
- 1;
- 3Oxazine;
9.Diversity oriented heterocyclizations of pyruvic acids, aldehydes and 5-amino-N-aryl-1H-pyrazole-4-carboxamides: Catalytic and temperature control of chemoselectivity

机译：丙酮酸，醛和5-氨基-N-芳基-1H-吡唑-4-羧酰胺的多样性导向杂环：化学选择性的催化和温度控制
- 作者：Sakhno Y.I.;Shishkina S.V.;Shishkin O.V.;Musatov V.I.;Vashchenko E.V.;Desenko S.M.;Chebanov V.A.
- 期刊名称：《Molecular diversity》 | 2010年第3期
- 5-Aminopyrazole-4-carboxamide;
- Microwave synthesis;
- Multicomponent reaction (MCR);
- Pyruvic acid;
- Selectivity;
- Ultrasonication;
10.Facile and efficient approach for the synthesis of spirocyclopropylbarbiturates and 3-substituted-1,1,2,2-tetracyanocyclopropanes using N-halosulfonamides

机译：使用N-卤代磺酰胺合成螺环丙基巴比妥酸酯和3-取代的1,1,2,2-四氰基环丙烷的简便有效方法
- 作者：Ghorbani-Vaghei Ramin;Maghbooli Yaser;Shahriari Azadeh;Mahmoodi Jafar
- 期刊名称：《Molecular diversity》 | 2016年第4期
11.Synthesis of pyrazolo[1,5-a]pyrimidine derivatives and their antifungal activities against phytopathogenic fungi in vitro

机译：吡唑并[1,5-a]嘧啶衍生物的合成及其对植物致病真菌的抗真菌活性
- 作者：Zhang Jin;Peng Ju-Fang;Bai Yu-Bin;Wang Ping;Wang Tao;Gao Jin-Ming;Zhang Zun-Ting
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Pyrazolo1;
- 5-apyrimidines;
- Chemoselectivity;
- Synthesized;
- Phytopathogenic fungi;
- Antifungal;
12.Substituted N-aminothioglycolurils containing thiosemicarbazone moiety and their cytotoxic activity in vitro

机译：含硫半脲部分的N-氨基硫代糖基尿嘧啶取代基及其体外细胞毒活性
- 作者：Gazieva Galina A.;Anikina Lada V.;Pukhov Sergei A.;Karpova Tatyana B.;Nelyubina Yulia V.;Kravchenko Angelina N.
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Thioglycolurils;
- Cyclic thiosemicarbazones;
- 5-Thioxohexahydroimidazo4;
- 5-dimidazol-2(1H)-one;
- Cytotoxic activity;
13.Synthesis of novel fused quinazolinone derivatives

机译：新型稠合喹唑啉酮衍生物的合成
- 作者：Mahdavi Mohammad;Lotfi Vahid;Saeedi Mina;Kianmehr Ebrahim;Shafiee Abbas
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Quinazolinone;
- Isatoic anhydride;
- Quinazolino3;
- 4-aquinazolinones;
- Isoinodolo2;
- 1-aquinazolino1;
- 2-cquinazolineones;
- Heterocycles;
- Cyclization;
14.Microbial diversification of Diels-Alder cycloadducts by whole cells of Penicillium brasilianum

机译：巴西青霉全细胞对Diels-Alder环加合物的微生物多样性作用
- 作者：Din Zia Ud;Fill Taicia P.;Carolina Donatoni M.;dos Santos Carolina A. A.;Brocksom Timothy J.;Rodrigues-Filho E.
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Diels-Alder cycloadducts;
- Penicillium brasilianum;
- Enantioselective biotransformation;
- OYE;
15.Transition metal-free one-pot synthesis of nitrogen-containing heterocycles

机译：不含过渡金属的一锅合成含氮杂环
- 作者：Kumari Simpal;Kishore Dharma;Paliwal Sarvesh;Chauhan Rajani;Dwivedi Jaya;Mishra Aakanksha
- 期刊名称：《Molecular diversity》 | 2016年第1期
- Heterocycles;
- Metal-free synthesis;
- One-pot reactions;
- Reviews;
16.In silico exploration of c-KIT inhibitors by pharmaco-informatics methodology: pharmacophore modeling, 3D QSAR, docking studies, and virtual screening

机译：通过药物信息学方法对c-KIT抑制剂进行计算机分析：药效团建模，3D QSAR，对接研究和虚拟筛选
- 作者：Chaudhari Prashant;Bari Sanjay
- 期刊名称：《Molecular diversity》 | 2016年第1期
- c-KIT inhibitors;
- Indolin-2-one;
- Pharmacophore;
- 3D QSAR;
- ZINC;
- Docking;
17.Sensitive electrospray mass spectrometry analysis of one-bead-one-compound peptide libraries labeled by quaternary ammonium salts

机译：季铵盐标记的一珠一化合物肽库的灵敏电喷雾质谱分析
- 作者：Ba?chor R.;Cydzik M.;Rudowska M.;Kluczyk A.;Stefanowicz P.;Szewczuk Z.
- 期刊名称：《Molecular diversity》 | 2012年第3期
- Derivatization of peptides;
- ESI-MS/MS;
- Fixed charge tag;
- Linker design;
- OBOC;
- Quaternary ammonium salts;
18.Focused enumeration and assessing the structural diversity of scaffold libraries: Conformationally restricted bicyclic secondary diamines

机译：重点列举和评估支架文库的结构多样性：构象受限的双环仲二胺
- 作者：Grygorenko O.O.;Prytulyak R.;Volochnyuk D.M.;Kudrya V.;Khavryuchenko O.V.;Komarov I.V.
- 期刊名称：《Molecular diversity》 | 2012年第3期
19.Three-component reactions of isocyanides, dialkyl acetylenedicarboxylates, and trans-cinnamoyl chlorides for the synthesis of highly functionalized 2-vinyl furans

机译：异氰酸酯，乙炔二羧酸二烷基酯和反式肉桂酰氯的三组分反应，用于合成高度官能化的2-乙烯基呋喃
- 作者：Esmaeili A.A.;Zangouei M.;Hosseinabadi R.;Fakhari A.R.
- 期刊名称：《Molecular diversity》 | 2012年第1期
- 2-vinyl furan;
- Alkyl isocyanide;
- Dialkyl acetylenedicarboxylate;
- Furan synthesis;
- MCR;
- Multi-component cyclization;
- Trans-cinnamoyl chloride;
20.VCl _3 catalyzed imine-based multicomponent reactions for the facile access of functionalized tetrahydropyridines and β-amino carbonyls

机译：VCl _3催化的基于亚胺的多组分反应，可轻松获得功能化的四氢吡啶和β-氨基羰基化合物
- 作者：Pal S.;Choudhury L.H.;Parvin T.
- 期刊名称：《Molecular diversity》 | 2012年第1期
- β-Amino carbonyls;
- MCRs;
- Multicomponent reactions;
- Tetrahydropyridines;
- VCl _3;
21.Synthesis and In vitro inhibition properties of oligonucleotide conjugates carrying amphipathic proline-rich peptide derivatives of the sweet arrow peptide (SAP)

机译：带有甜箭肽（SAP）的两亲富脯氨酸肽衍生物的寡核苷酸缀合物的合成和体外抑制特性
- 作者：Grijalvo S.;Eritja R.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- Antisense oligonucleotides;
- Cellular uptake;
- Luciferase;
- Oligonucleotide- peptide conjugates;
- Phosphorothioate;
- Sweet arrow peptide;
22.The generation of purinome-targeted libraries as a means to diversify ATP-mimetic chemical classes for lead finding

机译：以嘌呤组为靶标的文库的生成，是使ATP模拟化学类多样化以进行铅发现的一种方法
- 作者：Felder E.R.;Badari A.;Disingrini T.;Mantegani S.;Orrenius C.;Avanzi N.;Isacchi A.;Salom B.
- 期刊名称：《Molecular diversity》 | 2012年第1期
- ATPase inhibitors;
- Chemical space;
- Combinatorial chemistry;
- Compound collection;
- Drug design;
- Fragment based;
- Kinase inhibitors;
- Kinase selectivity;
- Solid phase synthesis;
23.QSAR classification of metabolic activation of chemicals into covalently reactive species

机译：将化学物质代谢活化为共价反应性物质的QSAR分类
- 作者：Liew C.Y.;Pan C.;Tan A.;Ang K.X.M.;Yap C.W.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- Ensemble;
- Prediction;
- QSAR;
- QSTR;
- Reactive metabolite;
- Screening software;
- Toxicity;
24.A novel and efficient one-pot four-component tandem approach for the synthesis of pyran derivatives

机译：一种新颖高效的一锅四组分串联合成吡喃衍生物的方法
- 作者：Zhang Z.;Xu Y.;Zheng J.;Li B.;Li Y.
- 期刊名称：《Molecular diversity》 | 2012年第3期
- Four-component reaction;
- Pd/C;
- Pyran derivatives;
- Tandem reaction;
25.Scaffold hopping for identification of novel D _2 antagonist based on 3D pharmacophore modelling of illoperidone analogs

机译：基于illoperidone类似物的3D药效团建模，支架跳跃法用于鉴定新型D _2拮抗剂
- 作者：Dash R.C.;Bhosale S.H.;Shelke S.M.;Suryawanshi M.R.;Kanhed A.M.;Mahadik K.R.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- 3D-QSAR;
- Docking study;
- Dopamine D _2 antagonist;
- Homology modeling;
- In silico screening;
- Pharmacophore;
26.Ionic liquid-supported synthesis of dihydroquinazolines and tetrahydroquinazolines under microwave irradiation

机译：微波辐射下离子液体负载的二氢喹唑啉和四氢喹唑啉的合成
- 作者：Hsu H.-Y.;Tseng C.-C.;Matii B.;Sun C.-M.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- Green chemistry;
- Ionic liquid support;
- Microwave-assisted synthesis;
- Tetrahydroquinazolines;
27.Synthesis of 3-aryl-1,2,4-benzotriazines via intramolecular cyclization of solid-supported o-hydrazidoanilines

机译：固体负载的邻羟基苯二甲胺分子内环化合成3-芳基-1,2,4-苯并三嗪
- 作者：Edwar Cortés;Luciana Méndez;Ernesto G. Mata;Rodrigo Abonia;Jairo Quiroga;Braulio Insuasty
- 期刊名称：《Molecular diversity》 | 2012年第4期
- Solid-phase organic synthesis;
- Aromatic nucleophilic substitution (SNAr);
- Hydrazidoanilines;
- 1;
- 2;
- 4-Benzotriazines;
28.Synthesis, crystal structure and biological activity of novel anthranilic diamide insecticide containing alkyl ether group

机译：新型含烷基醚基邻氨基苯甲酰胺类杀虫剂的合成，晶体结构和生物活性
- 作者：Yu Zhao;Li-ping Xu;Jun Tong;Yong-qiang Li;Li-xia Xiong;Fang Li;Li-na Peng;Zheng-ming Li
- 期刊名称：《Molecular diversity》 | 2012年第4期
- Anthranilic diamide;
- Ryanodine receptor;
- Synthesis;
- Insecticidal activity;
29.Organocatalytic three-component cascade reaction for the synthesis of spiro[indeno[1,2-b]furan]-triones

机译：有机催化三组分级联反应合成螺[茚并[1,2-b]呋喃]-三酮
- 作者：Ahadi S.;Abaszadeh M.;Bazgir A.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- 3-Bromo-4-hydroxycoumarin;
- Organocatalysis;
- Spiroindeno1;
- 2-bfuran-triones;
30.Identification of furo[3', 2':3,4]naphtho[1,2-d]imidazole derivatives as orally active and selective inhibitors of microsomal prostaglandin E _2 synthase-1 (mPGES-1)

机译：鉴定呋喃[3'，2'：3,4]萘并[1,2-d]咪唑衍生物作为微粒体前列腺素E _2合酶-1（mPGES-1）的口服活性和选择性抑制剂
- 作者：Tseng C.-H.;Tzeng C.-C.;Shih P.-K.;Yang C.-N.;Chuang Y.-C.;Peng S.-I.;Lin C.-S.;Wang J.-P.;Cheng C.-M.;Chen Y.-L.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- Furo3';
- 2':3;
- 4naphtho1;
- 2-dimidazole derivatives;
- MPGES-1 inhibitor;
- Oral anti-inflammatory drug;
31.Generation of Diverse 1-imidazolylisoquinolines via silver triflate-catalyzed reaction of 2-alkynylbenzaldoxime with imidazole

机译：三氟甲磺酸银催化的2-炔基苯甲肟与咪唑的反应生成不同的1-咪唑基喹啉
- 作者：Xiao Q.;Ye S.;Zheng D.;Zhang L.;Wu J.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- 1-imidazolylisoquinoline;
- 2-alkynylbenzaldoxime;
- Benzoimidazole;
- Imidazole;
- Silver triflate electronic;
32.3D-QSAR and molecular docking analysis of biphenyl amide derivatives as p38α mitogen-activated protein kinase inhibitors

机译：3D-QSAR和联苯酰胺衍生物作为p38α丝裂原活化的蛋白激酶抑制剂的分子对接分析
- 作者：Ambure P.S.;Gangwal R.P.;Sangamwar A.T.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- Biphenyl amide;
- CoMFA;
- CoMSIA;
- Glide;
- LeapFrog;
- Molecular docking;
- P38 MAP kinase;
33.Molecular docking and receptor-specific 3D-QSAR studies of acetylcholinesterase inhibitors

机译：乙酰胆碱酯酶抑制剂的分子对接和受体特异性3D-QSAR研究
- 作者：Pran Kishore Deb;Anuradha Sharma;Poonam Piplani;Raghuram Rao Akkinepally
- 期刊名称：《Molecular diversity》 | 2012年第4期
- Acetylcholinesterase inhibitors;
- Molecular docking;
- Consensus scoring;
- 3D-QSAR;
- ADME prediction;
34.Combining click-multicomponent reaction: One-pot synthesis of triazolyl methoxy-phenyl indazolo[2,1-b]phthalazine-trione derivatives

机译：单击多组分反应的组合：一锅合成三唑基甲氧基-苯基吲唑并[2,1-b]酞嗪-三酮衍生物
- 作者：Salehi P.;MaGee D.I.;Dabiri M.;Torkian L.;Donahue J.
- 期刊名称：《Molecular diversity》 | 2012年第2期
- 1;
- 2;
- 3-triazole;
- Click chemistry;
- MCR;
- Multicomponent reaction;
- One-pot reaction;
- Phthalhydrazide;
35.GSA: a GPU-accelerated structure similarity algorithm and its application in progressive virtual screening

机译：GSA：GPU加速结构相似算法及其在渐进式虚拟筛选中的应用
- 作者：Xin Yan;Qiong Gu;Feng Lu;Jiabo Li;Jun Xu
- 期刊名称：《Molecular diversity》 | 2012年第4期
- Structure similarity;
- GPU;
- Progressive virtual screening;
36.Magnetic nanoparticles catalyzed synthesis of diverse N-Heterocycles

机译：磁性纳米粒子催化合成各种N-杂环
- 作者：Kidwai M.;Jain A.;Bhardwaj S.
- 期刊名称：《Molecular diversity》 | 2012年第1期
- Diverse synthesis;
- Fe_3O _4 nanoparticles;
- Magnetically separable;
- Multicomponent reactions (MCRs);
- N-heterocycles;
37.Catalyst-free multicomponent synthesis of novel adamantyl-containing tetrahydropyrimidine carboxylates

机译：新型含金刚烷基四氢嘧啶羧酸盐的无催化剂多组分合成
- 作者：Kalita Utpalparna;Kaping Shunan;Vishwakarma Jai Narain
- 期刊名称：《Molecular diversity》 | 2016年第3期
- 1-Adamantanamine;
- Tetrahydropyrimidine;
- Multicomponent reactions;
- MCRs;
- beta-Enaminoesters;
- Cyclization;
- Heterocycles;
38.Synthesis of multi-functionalized benzofurans through the condensation of ninhydrin and phenols using SSA as a recyclable heterogeneous acid catalyst

机译：使用SSA作为可循环利用的非均相酸催化剂，通过茚三酮与苯酚的缩合反应合成多功能苯并呋喃
- 作者：Kundu Ashis;Pramanik Animesh
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Benzofurans;
- Ninhydrin;
- Phenols;
- Silica sulfuric acid;
- Condensation reaction;
39.One-pot tandem Ugi-4CR/Ar approach to highly functionalized quino[2,3-b][1,5]benzoxazepines

机译：一锅串联Ugi-4CR / Ar方法制备高度官能化的喹[2,3-b] [1,5]苯并x氮平
- 作者：Ghandi Mehdi;Zarezadeh Nahid;Abbasi Alireza
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Ugi reaction;
- Quino2;
- 3-b1;
- 5 benzoxazepine;
- 2-Chloroquinoline-3-carbaldehyde;
- SNAr reaction;
- MCRs;
40.Synthesis and antitumor evaluation of novel sulfonylcycloureas derived from nitrogen mustard

机译：氮芥制新型磺酰基环脲的合成及抗肿瘤评价
- 作者：Cheloufi H.;Belhani B.;Ouk T. S.;Zerrouki R.;Aouf N. -E.;Berredjem M.
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Cancer;
- Sulfonamides;
- Nitrogen mustard;
- Sulfonylcycloureas;
- Antitumor;
41.Combinatorial synthesis of deuterium-enriched (S)-oxybutynin

机译：富氘（S）-奥昔布宁的组合合成
- 作者：Li Feng;Jiang Wenfeng;Czarnik Anthony W.;Li Wenbao
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Deuterium;
- Oxybutynin;
- Combinatorial chemistry;
- Derivatives;
42.Synthesis of isoindolin-1-one derivatives via multicomponent reactions of methyl 2-formylbenzoate and intramolecular amidation

机译：通过2-甲酰基苯甲酸甲酯和分子内酰胺化的多组分反应合成异吲哚啉-1-酮衍生物
- 作者：Lei Jie;Xu Zhi-Gang;Li Shi-Qiang;Xu Jia;Zhu Jin;Chen Zhong-Zhu
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Cyclization;
- Heterocycles;
- Ugi-type multicomponent reactions;
- UDC strategy;
- Intramolecular amidation;
- One-pot procedure;
- MCRs;
43.Microwave-assisted Synthesis and antifungal activity of coumarin[8,7-e][1,3] oxazine derivatives

机译：香豆素[8,7-e] [1,3]恶嗪衍生物的微波辅助合成及其抗真菌活性
- 作者：Zhang Ming-Zhi;Zhang Rong-Rong;Yin Wen-Zheng;Yu Xiang;Zhang Ya-Ling;Liu Pin;Gu Yu-Cheng;Zhang Wei-Hua
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Coumarin;
- Oxazine;
- Microwave-assisted synthesis;
- Mannich reaction;
- Antifungal activity;
- SAR;
44.Molecular diversity of spirooxindoles. Synthesis and biological activity

机译：spirooxindoles的分子多样性。合成与生物活性
- 作者：Pavlovska Tetyana L.;Redkin Ruslan Gr;Lipson Victoria V.;Atamanuk Dmytro V.
- 期刊名称：《Molecular diversity》 | 2016年第1期
45.Synthesis of tricyclic quinazolinones via intramolecular cyclization of 3-(2-aminoalkyl)-2-(phenylamino)quinazolin-4(3H)-ones

机译：通过3-（2-氨基烷基）-2-（苯基氨基）喹唑啉-4（3H）-的分子内环化反应合成三环喹唑啉酮
- 作者：Yang Xuhong;Wu Minghu;Sun Shaofa;Huang Changfeng;Guo Haibing;Wang Jian;Lee John;Xing Yalan
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Tricyclic quinazoline;
- Intramolecular cyclization;
- Guanidines;
46.In silico evaluation, molecular docking and QSAR analysis of quinazoline-based EGFR-T790M inhibitors

机译：基于喹唑啉的EGFR-T790M抑制剂的计算机评估，分子对接和QSAR分析
- 作者：Asadollahi-Baboli M.
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Quinazolines;
- Molecular docking;
- GA-ANN;
- MARS;
- EGFR;
- Descriptor selection;
47.Synthesis of 3-heteroarylchromones via a photochemical reaction

机译：通过光化学反应合成3-杂芳基色酮
- 作者：Yang Qian;He Yun;Wang Tao;Zeng Lingyu;Zhang Zunting
- 期刊名称：《Molecular diversity》 | 2016年第1期
- 3-Iodochromen-4-ones;
- Photochemical reaction;
- Synthesis;
- 3-Heteroarylchromones;
48.Discovery of new Mycobacterium tuberculosis proteasome inhibitors using a knowledge-based computational screening approach (vol 19, pg 1003, 2015)

机译：使用基于知识的计算筛选方法发现新的结核分枝杆菌蛋白酶体抑制剂（第19卷，第1003页，2015年）
- 作者：Mehra Rukmankesh;Chib Reena;Munagala Gurunadham;Yempalla Kushalava Reddy;Khan Inshad Ali;Singh Parvinder Pal;Khan Farrah Gul;Nargotra Amit
- 期刊名称：《Molecular diversity》 | 2016年第1期
49.Hybrids: a new paradigm to treat Alzheimer's disease

机译：杂种：治疗阿尔茨海默氏病的新范例
- 作者：Singh Manjinder;Kaur Maninder;Chadha Navriti;Silakari Om
- 期刊名称：《Molecular diversity》 | 2016年第1期
- Acetylcholinesterase inhibitors;
- Hybrids;
- Multi-target;
- Alzheimer's disease;
- Tacrine;
- beta-Amyloid;
50.Synthesis and biological evaluation of novel tamoxifen-1,2,4-triazole conjugates

机译：新型他莫昔芬-1,2,4-三唑共轭物的合成及生物学评价
- 作者：Murty M. S. R.;Katiki Mohana Rao;Nanubolu Jagadeesh Babu;Garimella Srujana;Polepalli Sowjanya;Jain Nishant;Buddana Sudheer Kumar;Prakasham R. S.
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Tamoxifen;
- 1;
- 2;
- 4-Triazole;
- McMurry coupling;
- Piperazines;
- Antibacterial;
51.I-2-mediated amination/cyclization of ketones with 2-aminopyridines under high-speed ball milling: solvent- and metal-free synthesis of 2,3-substituted imidazo[1,2-a]pyridines and zolimidine

机译：在高速球磨条件下，I-2-介导的2-氨基吡啶对酮的胺化/环化反应：无溶剂和无金属的2,3-取代的咪唑并[1,2-a]吡啶和咪唑烷的合成
- 作者：Wang Fang-Jian;Xu Hui;Xin Ming;Zhang Ze
- 期刊名称：《Molecular diversity》 | 2016年第3期
- High-speed ball milling;
- Imidazo1;
- 2-apyridines;
- Iodine;
- Solvent-free;
- Metal-free;
- Zolimidine;
- Cyclization;
- Heterocycle synthesis;
52.Novel domino procedures for the synthesis of chromene derivatives and their isomerization

机译：色烯衍生物的合成及其异构化的新型多米诺法
- 作者：Zonouzi Afsaneh;Izakian Zakieh;Ng Seik Weng
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Domino reaction;
- Michael addition;
- Oxo-Diels-Alder;
- Chromene;
- Isomerization;
- DABCO;
- Iminolactone;
- MCRs;
53.One-pot synthesis, biological evaluation, and docking study of new chromeno-annulated thiopyrano[2,3-c]pyrazoles

机译：一锅合成，生物评价和对接新的色诺环氧基吡喃并[2,3-c]吡唑类化合物的对接研究
- 作者：Parmar Bhagyashri D.;Sutariya Tushar R.;Brahmbhatt Gaurangkumar C.;Parmar Narsidas J.;Kant Rajni;Gupta Vivek K.;Murumkar Prashant R.;Sharma Mayank Kumar;Yadav Mange Ram
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Thiopyrano2;
- 3-cpyrazole;
- HmimHSO4;
- Pyrazole-5-thione;
- Domino-Knoevenagel-hetero-Diels-Alder reaction;
- Microwave synthesis;
- Docking;
- Ionic liquid;
54.Cerium oxide-catalyzed multicomponent condensation approach to spirooxindoles in water

机译：氧化铈催化的多组分缩合方法制备水中的螺菌毒素
- 作者：Shrestha Rajeev;Sharma Kavita;Lee Yong Rok;Wee Young-Jung
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Cerium oxide nanoparticles;
- Spirooxindoles;
- Antioxidant;
- Antibacterial;
- MCRs;
55.Synthesis and antifungal activity of dehydroabietic acid-based 1,3,4-thiadiazole-thiazolidinone compounds

机译：脱氢松香酸基1,3,4-噻二唑-噻唑烷酮类化合物的合成及抗真菌活性
- 作者：Chen Naiyuan;Duan Wengui;Lin Guishan;Liu Luzhi;Zhang Rui;Li Dianpeng
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Dehydroabietic acid;
- Thiadiazole;
- Thiazolidinone;
- Antifungal;
- Activity;
- Natural product;
56.Identification of potential ACAT-2 selective inhibitors using pharmacophore, SVM and SVR from Chinese herbs

机译：使用中草药的药效团，SVM和SVR鉴定潜在的ACAT-2选择性抑制剂
- 作者：Qiao Lian-sheng;Zhang Xian-bao;Jiang Lu-di;Zhang Yan-ling;Li Gong-yu
- 期刊名称：《Molecular diversity》 | 2016年第4期
- ACAT-2;
- Hyperlipidemia;
- Pharmacophore;
- SVM;
- SVR;
- Virtual screening;
- Traditional Chinese medicine;
57.Design, synthesis and biological evaluation of novel 1,2,3-triazolyl -hydroxy alkyl/carbazole hybrid molecules

机译：新型1,2,3-三唑基-羟基烷基/咔唑杂化分子的设计，合成及生物学评价
- 作者：Rad Mohammad Navid Soltani;Behrouz Somayeh;Behrouz Marzieh;Sami Akram;Mardkhoshnood Mehdi;Zarenezhad Ali;Zarenezhad Elham
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Antifungal;
- Antibacterial;
- Carbazole;
- beta-Hydroxy 1;
- 2;
- 3-triazole;
- Mycobacterium P450DM;
58.Non-dopamine receptor ligands for the treatment of Parkinson's disease. Insight into the related chemical/property space

机译：非多巴胺受体配体，用于治疗帕金森氏病。洞察相关的化学/财产空间
- 作者：Ivanenkov Yan A.;Veselov Mark S.;Chufarova Nina V.;Majouga Alexander G.;Kudryavceva Anna A.;Ivachtchenko Alexandre V.
- 期刊名称：《Molecular diversity》 | 2016年第1期
- Bioisosteres;
- Descriptors;
- Diversity;
- Drugs;
- Non-dopamine;
- Parkinson's disease;
59.Novel RIPK3 inhibitors discovered through a structure-based approach exert post-ischemic neuroprotection

机译：通过基于结构的方法发现的新型RIPK3抑制剂发挥缺血后神经保护作用
- 作者：Fayaz S. M.;Kumar V. S. Suvanish;Davis Charles K.;Rajanikant G. K.
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Necroptosis;
- Ischemic stroke;
- Dual ensemble screening (DES);
- Post-ischemic neuroprotection;
60.Calixdrugs: calixarene-based clusters of established therapeutic drug agents

机译：Calixdrugs：已建立治疗药物的基于杯芳烃的簇
- 作者：Pur Fazel Nasuhi
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Calixdrug;
- Cluster;
- Calixarene;
- Calixpenam;
- Calixcephem;
- Calixtyrosol;
- Calixplatin;
61.The present state of the art in expression, production and characterization of monoclonal antibodies

机译：表达，生产和表征单克隆抗体的最新技术
- 作者：Gaughan Christopher L.
- 期刊名称：《Molecular diversity》 | 2016年第1期
62.Skeletal modifications of beta-carboline alkaloids and their antiviral activity profile

机译：β-咔啉生物碱的骨架修饰及其抗病毒活性
- 作者：Yang Yan;Huang Yuanqiong;Song Hongjian;Liu Yuxiu;Wang Lizhong;Wang Qingmin
- 期刊名称：《Molecular diversity》 | 2016年第4期
- beta-Carboline alkaloids;
- Tobacco mosaic virus;
- X-ray structure;
- Anti-TMV;
- Structure-activity relationship;
63.Active site fingerprinting and pharmacophore screening strategies for the identification of dual inhibitors of protein kinase C and poly (ADP-ribose) polymerase-1 (PARP-1)

机译：活性部位指纹图谱和药效基团筛选策略，用于鉴定蛋白激酶C和聚（ADP-核糖）聚合酶-1（PARP-1）的双重抑制剂
- 作者：Chadha Navriti;Silakari Om
- 期刊名称：《Molecular diversity》 | 2016年第3期
64.Tuning the Lewis acid phenol -prenylation as a molecular diversity tool

机译：调节路易斯酸苯酚-异戊二烯化作为分子多样性工具
- 作者：Jaeger Sebastian N.;Porta Exequiel O. J.;Labadie Guillermo R.
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Prenylated natural products;
- Phenols;
- Friedel-Crafts alkylation;
- Selective C-prenylation;
65.Synthesis, reactivity, and biological activity of 5-aminouracil and its derivatives

机译：5-氨基尿嘧啶及其衍生物的合成，反应和生物活性
- 作者：Shaker Raafat Mohamed;Abd Elrady Mohamed;Sadek Kamal Usef
- 期刊名称：《Molecular diversity》 | 2016年第1期
- 5-Aminouracil;
- Synthesis;
- Reactivity;
- Chemotherapeutic interest;
- Pharmacological interest;
66.High-throughput screening against 6.1 million structurally diverse, lead-like compounds to discover novel ROCK inhibitors for cerebral injury recovery

机译：针对610万种结构多样的铅样化合物进行高通量筛选，以发现用于大脑损伤恢复的新型ROCK抑制剂
- 作者：Gong Haoling;Yuan Zhicheng;Zhan Liping
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Rho-associated protein kinase;
- High-throughput screening;
- Neuroregeneration;
- Cerebral injury;
- CNS;
- Blood-brain barrier;
67.Design, synthesis, insecticidal activity, and structure-activity relationship (SAR): studies of novel triazone derivatives containing a urea bridge group based on transient receptor potential (TRP) channels

机译：设计，合成，杀虫活性和结构活性关系（SAR）：基于瞬态受体电位（TRP）通道的含有脲桥基的新型三氮唑衍生物的研究
- 作者：Yang Yan;Liu Yuxiu;Song Hongjian;Li Yongqiang;Wang Qingmin
- 期刊名称：《Molecular diversity》 | 2016年第4期
- 4;
- 5-Dihydro-1;
- 2;
- 4-triazin-3(2H)-one;
- Urea bridge;
- Biurea bridge;
- Transient receptors potential (TRP) channels;
- Insecticidal activity;
- Structure-activity relationship;
68.Ring-closing metathesis as key step in the synthesis of Luffarin I, 16-epi-Luffarin I and Luffarin A

机译：闭环置换是合成Luffarin I，16-epi-Luffarin I和Luffarin A的关键步骤
- 作者：Urosa Aitor;Marcos Isidro S.;Diez David;Plata Gabriela B.;Padron Jose M.;Basabe Pilar
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Ring-closing metathesis;
- Marine natural products;
- Luffarins;
- Yamaguchi esterefication;
- Cancer;
- Faulkner oxidation;
69.A green synthesis in water of novel (1,5,3-dithiazepan-3-yl)alkanoic acids by the multicomponent reaction of amino acids, O, and 1,2-ethanedithiol

机译：通过氨基酸，O和1,2-乙二硫醇的多组分反应在水中绿色合成新型（1,5,3-二硫杂氮杂-3-基）链烷酸
- 作者：Khabibullina Guzel R.;Fedotova Ekaterina S.;Akhmetova Vnira R.;Mesheryakova Ekaterina S.;Khalilov Leonard M.;Ibragimov Askhat G.
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Multicomponent reaction;
- MRCs;
- Amino acids;
- (1;
- 5;
- 3-Dithiazepan-3-yl)alkanoic acids;
- Water;
- Green synthesis;
70.A novel four- and pseudo-five-component reaction: unexpected efficient one-pot synthesis of 4H-thiopyran derivatives

机译：一种新颖的四和假五组分反应：出乎意料的高效一锅合成4H-噻喃衍生物
- 作者：Mobinikhaledi Akbar;Bodaghifard Mohammad Ali;Asadbegi Sajad
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Thiopyrans;
- Isothiocyanate;
- Multicomponent reaction;
- MCR;
- One-pot reaction;
- Michael addition;
71.Synthesis and preliminary biological evaluations of (+)-isocampholenic acid-derived amides

机译：（+）-异马来酸衍生酰胺的合成及初步生物学评价
- 作者：Groselj Uros;Golobic Amalija;Knez Damijan;Hrast Martina;Gobec Stanislav;Riko Sebastijan;Svete Jurij
- 期刊名称：《Molecular diversity》 | 2016年第3期
72.A new synthesis of -aryl uracils from aryl thiols and 6-amino uracils in the presence of NCS

机译：在NCS存在下由芳基硫醇和6-氨基尿嘧啶合成新的-芳基尿嘧啶
- 作者：Khalili Gholamhossein
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Uracil;
- Sulfenylchloride;
- Thiol;
- N-Chlorosuccinimide;
73.Ethyl 3-(2,4-dioxocyclohexyl)propanoate as a novel precursor for N-substituted 4,4a,5,6-tetrahydroquinoline-2,7(1H,3H)-diones and their corresponding 3,4-dihydro-7-hydroxyquinolin-2(1H)-ones and 7-hydroxyquinolin-2(1H)-ones synthesis

机译：3-（2,4-二氧环己基）丙酸乙酯作为N-取代的4,4a，5,6-四氢喹啉-2,7（1H，3H）-二酮及其相应的3,4-二氢-7-的新型前体羟基喹啉-2（1H）-one和7-羟基喹啉-2（1H）-one的合成
- 作者：Thakur Vandna;Sharma Dharminder;Das Pralay
- 期刊名称：《Molecular diversity》 | 2016年第1期
- Cyclohexane-1;
- 3-dione;
- Tetrahydroquinoline-2;
- 7-dione;
- 7-Hydroxy-quinlin-2(1H)-one;
- Dehydrogenative aromatization;
- Heterocycles;
- Microwave irradiation;
74.New insights into PDE4B inhibitor selectivity: CoMFA analyses and molecular docking studies

机译：PDE4B抑制剂选择性的新见解：CoMFA分析和分子对接研究
- 作者：Guariento Sara;Bruno Olga;Fossa Paola;Cichero Elena
- 期刊名称：《Molecular diversity》 | 2016年第1期
- Phosphodiesterases;
- PDE4B inhibitors;
- PDE4D;
- Molecular docking;
- Selectivity;
- CoMFA;
75.A facile, regioselective synthesis of novel 3-(N-phenylcarboxamide)pyrazolo[1,5-a]pyrimidine analogs in the presence of KHSO in aqueous media assisted by ultrasound and their antibacterial activities

机译：在超声辅助的水介质中，在KHSO存在下，新型3-（N-苯基羧酰胺）吡唑并[1,5-a]嘧啶类似物的区域选择性选择性合成及其抗菌活性
- 作者：Kaping Shunan;Boiss Ivee;Singha Laishram Indira;Helissey Philippe;Vishwakarma Jai N.
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Pyrazolopyrimidines;
- 5-Aminopyrazoles;
- Condensation;
- Formylation;
- Antibacterial;
- Ultrasound irradiation;
- X-ray crystallography;
76.Highly efficient synthesis of quinoxaline derivatives from 1,2-benzenediamine and -aminoxylated 1,3-dicarbonyl compounds

机译：由1,2-苯二胺和-氨基氧合的1,3-二羰基化合物高效合成喹喔啉衍生物
- 作者：Yan Jianwei;Xu Yanhong;Zhuang Fangfang;Tian Jie;Zhang Guisheng
- 期刊名称：《Molecular diversity》 | 2016年第2期
- alpha-Aminoxylated dicarbonyl compounds;
- Quinoxaline;
- Pyrazine;
- Pyridopyrazine;
- Benzoxazin-2-one;
77.Topological sub-structural molecular design (TOPS-MODE): a useful tool to explore key fragments of human adenosine receptor ligands

机译：拓扑子结构分子设计（TOPS-MODE）：探索人腺苷受体配体关键片段的有用工具
- 作者：Saiz-Urra Liane;Teijeira Marta;Rivero-Buceta Virginia;Morales Helguera Aliuska;Celeiro Maria;Carmen Teran Ma;Besada Pedro;Borges Fernanda
- 期刊名称：《Molecular diversity》 | 2016年第1期
- A(3) adenosine receptor agonist;
- QSAR;
- TOPS-MODE;
- Ddrug discovery;
- Fragment contributions;
78.Ring opening of epoxides with C-nucleophiles

机译：环氧化物与C-亲核试剂的开环
- 作者：Faiz Sadia;Zahoor Ameer Fawad
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Epoxides;
- Ring opening reactions;
- C-Nucleophiles;
- Enolates;
- Dithianes;
79.Re2O7-catalyzed formal [3+2] cycloaddition for diverse naphtho[1,2-b]furan-3-carboxamides and their biological evaluation

机译：Re2O7催化的正式[3 + 2]环加成反应制备各种萘[1,2-b]呋喃-3-羧酰胺及其生物学评价
- 作者：Xia Likai;Idhayadhulla Akber;Lee Yong Rok
- 期刊名称：《Molecular diversity》 | 2016年第1期
- Naphtho1;
- 2-bfuran-3-carboxamides;
- Anti-tyrosinase;
- Antioxidant;
- Antibacterial activity;
- Cycloaddition;
80.Combinatorial synthesis of deuterium-enriched atorvastatin

机译：富氘阿托伐他汀的组合合成
- 作者：Li Feng;Jiang Wenfeng;Czarnik Anthony W.;Li Wenbao
- 期刊名称：《Molecular diversity》 | 2016年第2期
- Deuterium;
- Atorvastatin;
- Combinatorial chemistry;
- Deuterated derivatives;
81.Groebke-Blackburn-Bienaym, multicomponent reaction: emerging chemistry for drug discovery

机译：Groebke-Blackburn-Bienaym，多组分反应：用于药物发现的新兴化学
- 作者：Shaaban Saad;Abdel-Wahab Bakr F.
- 期刊名称：《Molecular diversity》 | 2016年第1期
- Diversity-oriented synthesis;
- DOS;
- Isocyanide multicomponent reactions;
- MCRs;
- Kinase inhibitors;
- Microwave;
- Passerini reaction;
- Ugi reaction;
82.Vanillic aldehydes for the one-pot synthesis of novel 2-oxo-1,2,3,4-tetrahydropyrimidines

机译：一锅合成新型2-氧-1,2,3,4-四氢嘧啶的香草醛
- 作者：Muskinja Jovana;Jankovic Nenad;Ratkovic Zoran;Bogdanovic Goran;Bugarcic Zorica
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Homogeneous catalysis;
- Heterogeneous catalysis;
- Multicomponent reactions (MCRs);
- Heterocycles;
83.Ethylene glycol promoted catalyst-free pseudo three-component green synthesis of bis(coumarin)s and bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s

机译：乙二醇促进双（香豆素）和双（3-甲基-1-苯基-1H-吡唑-5-醇）的无催化剂假三组分绿色合成
- 作者：Kauthale Sushama S.;Tekale Sunil U.;Jadhav Kavita M.;Pawar Rajendra P.
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Catalyst-free;
- Biscoumarins;
- Bispyrazoles;
- MCRs;
- Green chemistry;
84.Design and synthesis of novel protein kinase R (PKR) inhibitors

机译：新型蛋白激酶R（PKR）抑制剂的设计与合成
- 作者：Weintraub Sagiv;Yarnitzky Tali;Kahremany Shirin;Barrera Iliana;Viskind Olga;Rosenblum Kobi;Niv Masha Y.;Gruzman Arie
- 期刊名称：《Molecular diversity》 | 2016年第4期
- PKR inhibitors;
- C16;
- Benzoimidazole derivatives;
- Computer modelling;
85.Computational predictive models for P-glycoprotein inhibition of in-house chalcone derivatives and drug-bank compounds

机译：P-糖蛋白抑制室内查尔酮衍生物和药物库化合物的计算预测模型
- 作者：Trieu-Du Ngo;Thanh-Dao Tran;Minh-Tri Le;Khac-Minh Thai
- 期刊名称：《Molecular diversity》 | 2016年第4期
- Machine learning;
- Docking;
- P-glycoprotein;
- Chalcone;
- Drug bank;
86.Uniqueness: skews bit occurrence frequencies in randomly generated fingerprint libraries

机译：唯一性：歪曲随机生成的指纹库中的位出现频率
- 作者：Chen Nelson G.
- 期刊名称：《Molecular diversity》 | 2016年第3期
- Algorithm;
- Molecular modeling;
- Fingerprints;
- Simulation;
87.Microwave-assisted one-pot multi-component reaction:synthesis of novel and highly functionalized 3-(pyranyl)- and 3-(dihydropyridinyl)indole derivatives

机译：微波辅助一锅多组分反应：新型且高度官能化的3-（吡喃基）-和3-（二氢吡啶基）吲哚衍生物的合成
- 作者：Pallabi Borah;P. Seetham Naidu;Swarup Majumder;Pulak J. Bhuyan
- 期刊名称：《Molecular diversity》 | 2014年第4期
- Indole;
- Pyrane;
- Dihydropyridine;
- MCR;
- Multi-component reaction;
- Microwave-assisted reaction;
88.Trends in information theory-based chemical structure codification

机译：基于信息论的化学结构编码趋势
- 作者：Stephen J. Barigye;Yovani Marrero-Ponce;Facundo Pérez-Giménez;Danail Bonchev
- 期刊名称：《Molecular diversity》 | 2014年第3期
- Information theory;
- Chemical structure;
- Statistical pattern;
- Information indices;
- Shannon's entropy;
- Mutual;
- Conditional and joint entropies;
89.Predicting drug metabolism by CYP1A1, CYP1A2, and CYP1B1:insights from MetaSite, molecular docking and quantum chemical calculations

机译：通过CYP1A1，CYP1A2和CYP1B1预测药物代谢：MetaSite，分子对接和量子化学计算的见解
- 作者：Preeti Pragyan;Siddharth S. Kesharwani;Prajwal P. Nandekar;Vijay Rathod;Abhay T. Sangamwar
- 期刊名称：《Molecular diversity》 | 2014年第4期
- CYP1 family;
- MetaSite;
- Molecular docking;
- Chemical hardness;
- Local nucleophilicity;
- Metabolism prediction;
90.Iridium-catalyzed asymmetric ring-opening reactions of azabenzonorbornadiene with carboxylic acid nucleophiles

机译：氮杂苯并降冰片二烯与羧酸亲核试剂的铱催化不对称开环反应
- 作者：Yuhua Long;Wenling Wang;Dingqiao Yang;Han Jiang;Kaixuan Chen;Yali Fang
- 期刊名称：《Molecular diversity》 | 2014年第1期
- Iridium catalyst;
- Azabenzonorbornadiene;
- Carboxylic acid nucleophile;
- Asymmetry;
- Ring-opening reaction;
91.Discovery and identification of PIM-1 kinase inhibitors through a hybrid screening approach

机译：通过混合筛选方法发现和鉴定PIM-1激酶抑制剂
- 作者：Mingfeng Shao;Yiming Yuan;Kun Yu;Kai Lei;Guonian Zhu;Lijuan Chen;Mingli Xiang
- 期刊名称：《Molecular diversity》 | 2014年第2期
- PIM-1 inhibitor;
- Hybrid screening;
- Pharmacophore modeling;
- Inhibitory activity;
92.Synthesis of tetrahydropyrimidin-2-ones via FeCl_3 catalyzed one-pot domino reaction of amines, methyl propiolate, aromatic aldehydes, and urea

机译：FeCl_3催化的胺，丙酸甲酯，芳族醛和尿素的一锅多米诺反应合成四氢嘧啶-2-酮
- 作者：Li-Li Zhang;Jing Sun;Chao-Guo Yan
- 期刊名称：《Molecular diversity》 | 2014年第1期
- One-pot reaction;
- Domino reaction;
- Electrondeficient alkyne;
- Acrylate;
- Tetrahydropyrimidinone;
- FeCl_3;
93.An efficient strategy to syntheses of isoflavones

机译：合成异黄酮的有效策略
- 作者：Longzhu Liu;Qiuya Wang;Zunting Zhang;Qiong Zhang;Zichao Du;Dong Xue;Tingting Wang
- 期刊名称：《Molecular diversity》 | 2014年第4期
- Isoflavone;
- Photochemical reaction;
- Photochemistry;
- Synthesis;
- Ipriflavone;
94.Dual inhibitors of Janus kinase 2 and 3 (JAK2/3):designing by pharmacophore- and docking-based virtual screening approach

机译：Janus激酶2和3（JAK2 / 3）的双重抑制剂：通过基于药效团和对接的虚拟筛选方法设计
- 作者：Haneesh Jasuja;Navriti Chadha;Maninder Kaur;Om Silakari
- 期刊名称：《Molecular diversity》 | 2014年第2期
- Docking;
- Janus kinase 2;
- Janus kinase 3;
- Pharmacophore;
- Prime MM-GBSA;
- JAK2;
- JAK3;
95.A green, multicomponent, regio- and stereo-selective 1,3-dipolar cycloaddition of azides and azomethine ylides generated in situ with bifunctional dipolarophiles using PEG-400

机译：绿色，多组分，区域和立体选择性的1,3-偶氮环化叠氮化物和甲亚胺酰化物与双功能偶极亲和剂使用PEG-400原位生成
- 作者：Jayant Sindhu;Harjinder Singh;J. M. Khurana
- 期刊名称：《Molecular diversity》 | 2014年第2期
- Spiro compounds;
- Dipolar cycloaddition;
- Azomethine ylides;
- Multicomponent reactions (MCRs);
- Pyrrolidines;
- Thiazolidin-2;
- 4-dione;
- 1;
- 2;
- 3-Triazoles;
- PEG-400;
96.An in silico protocol for identifying mTOR inhibitors from natural products

机译：用于从天然产物中鉴定mTOR抑制剂的计算机模拟方案
- 作者：Lei Chen;Ling Wang;Qiong Gu;Jun Xu
- 期刊名称：《Molecular diversity》 | 2014年第4期
- mTOR;
- ZINC natural product database;
- 3D-QSAR pharmacophore model;
- Molecular docking;
- MM-GBSA analysis;
97.Tractable synthesis of multipurpose screening compounds with under-represented molecular features for an open access screening platform

机译：具有可扩展性的多用途筛选化合物的可合成合成，其分子特征不足以提供开放式筛选平台
- 作者：Felix Wilde;Edgar Specker;Martin Neuenschwander;Marc Nazaré;Anja Bodtke;Andreas Link
- 期刊名称：《Molecular diversity》 | 2014年第3期
- Reactive agents;
- Microwave synthesis;
- High-throughput screening;
- Open access databank;
- Targeted library;
98.Structural modification of an EGFR inhibitor that showed weak off-target activity against RET leading to the discovery of a potent RET inhibitor

机译：对RET显示弱的脱靶活性的EGFR抑制剂的结构修饰导致发现有效的RET抑制剂
- 作者：Qi-Zheng Sun;Yong Xu;Jing-Jing Liu;Chun-Hui Zhang;Ze-Rong Wang;Ren-Lin Zheng;Wen-Jing Wang;Lin-Li Li;Sheng-Yong Yang
- 期刊名称：《Molecular diversity》 | 2014年第2期
- Thyroid cancer;
- Rearranged during transfection (RET);
- Anticancer agents;
- EGFR;
- Kinases;
- Kinase inhibitorss;
99.Novel triazole alcohol antifungals derived from fluconazole: design, synthesis, and biological activity

机译：氟康唑衍生的新型三唑醇抗真菌剂：设计，合成和生物活性
- 作者：Hashemi Seyedeh Mahdieh;Badali Hamid;Faramarzi Mohammad Ali;Samadi Nasrin;Afsarian Mohammad Hosein;Irannejad Hamid;Emami Saeed
- 期刊名称：《Molecular diversity》 | 2015年第1期
- Antifungal activity;
- Azole antifungals;
- Fluconazole;
- Triazoles;
- Lanosterol 14 alpha-demethylase;
100.Synthesis and crystal structure of new heterocyles derived from saccharin and uracil carrying 1,2,4-oxadiazolylmethyl group (vol 19, pg 213, 2015)

机译：糖精和带有1,2,4-恶二唑基甲基的尿嘧啶衍生的新杂环的合成和晶体结构（第19卷，第213页，2015年）
- 作者：Durust Yasar;Ozer Besra;Kariuki Benson M.
- 期刊名称：《Molecular diversity》 | 2015年第2期

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