Enhanced effectiveness of medium-pressure ultraviolet lamps on human adenovirus 2 and its possible mechanism

摘要

There has been growing concern over human exposure to adenoviruses through drinking waterndue to their apparent high resistance to UV irradiation and the anticipated widespread use ofnultraviolet (UV) disinfection in drinking water treatment processes. However, most inactivationnstudies on adenoviruses were performed using only one type of UV technology—low-pressuren(LP) UV, and little is known about the effectiveness of different UV technologies such as medium-npressure (MP) UV or other polychromatic UV technologies. In this work, the kinetics and extent ofninactivation of a human adenovirus (adenovirus 2 (Ad2)) by both monochromatic LP andnpolychromatic MP UV were evaluated to determine the effectiveness of these UV technologies onnhuman adenoviruses. Inactivation of Ad2 by LP UV was very slow and only 0.87 and 2.17 log10ninactivation was achieved with UV doses of 30 and 90mJ/cm2n, respectively. However, inactivationnof Ad2 by MP UV was much faster and 2.19 and 5.36 log10 inactivation was observed with thensame UV doses (30 and 90mJ/cm2n, respectively). It appears that MP UV is more effective againstnAd2 than LP UV and the enhanced effectiveness of MP UV on Ad2 is likely due to its ability toninhibit the repair process in UV-irradiated Ad2.