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Real-World Experience with Type I Endoleaks after Endovascular Repair of the Thoracic Aorta

机译:胸主动脉腔内修复后I型内漏的真实经验

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摘要

Endoleaks are a frequent complication of thoracic endovascular aortic repair (TEVAR) and will likely increase in incidence with application of the technique to more complicated aortic anatomy and a wider range of thoracic aortic pathologies. Management generally consists of aggressive repair of Type I endoleaks; however, the natural history of Type I endoleaks after TEVAR remains largely unknown. The purpose of this study was to examine the incidence and characteristics of Type I endoleaks and to evaluate clinical outcomes of patients with Type I endoleaks after TEVAR. A single-center retrospective review was performed on all patients who underwent TEVAR over a 4-year period. Type I endoleaks were detected in 21 per cent (27 of 129) of patients on post-deployment aortography or CT angiography. During a mean follow-up of 750.63 ± 483 days, 59 per cent (16 of 27) closed spontaneously; 30 per cent (eight of 27) required secondary endovascular intervention; and 11 per cent (three of 27) have persisted with no increase in maximum aortic diameter. No patients have died or required open surgical conversion as a result of their Type I endoleak. Although accurate predictors of spontaneous resolution of Type I endoleaks have yet to be definitively characterized, our initial results suggest that it may be safe to observe small Type I endoleaks given that a large percentage resolve spontaneously and no endoleak-related deaths have occurred. [PUBLICATION ABSTRACT]
机译:内漏是胸腔内血管主动脉修复术(TEVAR)的常见并发症,随着该技术应用于更复杂的主动脉解剖结构和更广泛的胸主动脉病变,其发生率可能会增加。管理通常包括积极修复I型内漏;然而,在TEVAR后I型自然泄漏的自然历史仍然未知。这项研究的目的是检查TEVAR后I型内漏的发生率和特征,并评估I型内漏患者的临床结局。对所有接受TEVAR 4年以上治疗的患者进行了单中心回顾性研究。部署后主动脉造影或CT血管造影在21%(129例中的27例)患者中检测到I型内漏。在平均750.63±483天的随访中,有59%(27个中的16个)自发关闭。 30%(27人中的8%)需要进行二次血管内介入治疗;和11%(27个中的3个)持续存在,但主动脉最大直径没有增加。没有患者因I型内漏而死亡或需要进行开放外科手术。尽管尚不能确定I型内漏自发消退的准确预测指标,但我们的初步结果表明,鉴于大比例的I型内漏自发消退且未发生与内漏相关的死亡,观察到较小的I型内漏可能是安全的。 [出版物摘要]

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    《The American Surgeon》 |2010年第6期|p.599-605|共7页
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    JOSHUA D. ADAMS, M.D.,*t MARGARET C. TRACCI, M.D.,t SAHIR SABRI, M.D.,* KENNETH J. CHERRY, M.D.,+JOHN F. ANGLE, M.D.,* ALAN H. MATSUMOTO, M.D.,* JOHN A. KERN, M.D.+From the Departments of ^Radiology and tSurgery, University of Virginia Health System,Charlottesville, VirginiaPresented at the Annual Scientific Meeting and Postgraduate Course Program, Southeastern Surgical Congress, Savannah, GA, February 20-23, 2010.Address correspondence and reprint requests to Joshua D. Adams, M.D., P.O. Box 800170, Department of Radiology, 1215 Lee Street, Charlottesville, VA 22908. E-mail: jda2d@virginia. edu.;

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