Permanent Reversal of Diabetes in NOD Mice

摘要

We disagree with how J. noshio et al. (1) represent our published data on the permanent reversal of type 1 diabetes in NOD mice (2). Nishio et al. state (7) that "a FCA alone control was not included in the report by Kodama et al." (5). Further, in their response to our Technical Comment (4), they claim in numerous locations, including the abstract, that "[t]he experiments of Faustman et al. lack adequate controls," and "we continue to wonder why Faustman et al. have not performed the essential Freund's complete adjuvant alone control" (4). These statements in their papers are misrepresentations. These specific FCA (CFA)-alone controls were published in 2001 in our Journal of Clinical Investigation (JCI) paper (5). Nishio et al.