Single-Molecule DNA Sequencing of a Viral Genome

Timothy D. Harris; Phillip R. Buzby; Hazen Babcock; Eric Beer; Jayson Bowers; Ido Braslavsky; Marie Causey; Jennifer Colonell; James DiMeo; J. William Efcavitch; Eldar Giladi; Jaime Gill; John Healy; Mirna Jarosz; Dan Lapen; Keith Moulton; Stephen R. Qua

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Single-Molecule DNA Sequencing of a Viral Genome

机译：病毒基因组的单分子DNA测序

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The full promise of human genomics will be realized only when the genomes of thousands of individuals can be sequenced for comparative analysis. A reference sequence enables the use of short read length. We report an amplification-free method for determi

机译：只有对数千个个体的基因组进行测序以进行比较分析，才能实现人类基因组学的全部希望。参考序列可以使用较短的读取长度。我们报告了一种无需扩增的测定方法

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来源
《Science》 |2008年第5872期|p.106-109|共4页
作者
Timothy D. Harris; Phillip R. Buzby; Hazen Babcock; Eric Beer; Jayson Bowers; Ido Braslavsky; Marie Causey; Jennifer Colonell; James DiMeo; J. William Efcavitch; Eldar Giladi; Jaime Gill; John Healy; Mirna Jarosz; Dan Lapen; Keith Moulton; Stephen R. Qua;
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作者单位

Helicos BioSciences Corporation, One Kendall Square, Cambridge, MA 02139, USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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机译：ITR-SEQ，下一代测序测定，鉴定腺相关病毒载体介导的基因组编辑后体内的基因组DNA编辑位点
2. High contiguity de novo genome assembly and DNA modification analyses for the fungus fly, Sciara coprophila, using single-molecule sequencing [J] . Urban John M., Foulk Michael S., Bliss Jacob E., BMC Genomics . 2021,第1期

机译：Novo基因组组装和DNA改性分析真菌飞行，Sciara Coprophila使用单分子测序
3. Complete Genome Sequence of Pelosinus sp. Strain UFO1 Assembled Using Single-Molecule Real-Time DNA Sequencing Technology [J] . Steven D. Brown, Sagar M. Utturkar, Timothy S. Magnuson, Genome Announcements . 2014,第5期

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4. Single-molecule studies of the effect of spermidine on DNA mechanics and viral DNA packaging [C] . Nicholas Keller, Douglas E. Smith Optical trapping and optical micromanipulation IX. . 2012

机译：亚分子亚精胺对DNA力学和病毒DNA包装的影响的单分子研究
5. Using synthetic nanopores for single-molecule analyses: Detecting SNPs, trapping DNA molecules, and the prospects for sequencing DNA. [D] . Dimitrov, Valentin V. 2009

机译：使用合成的纳米孔进行单分子分析：检测SNP，捕获DNA分子以及DNA测序的前景。
6. Single-molecule DNA-mapping and whole-genome sequencing of individual cells [O] . Rodolphe Marie, Jonas N. Pedersen, Loic Bærlocher, 2018

机译：单分子DNA映射和单个细胞的全基因组测序
7. Single-molecule DNA-mapping and whole-genome sequencing of individual cells [O] . Rodolphe Marie, Jonas N. Pedersen, Loic Bærlocher, 2018

机译：单分子DNA映射和单个细胞的全基因组测序
8. Development of Single-Molecule DNA Sequencing Platform Based on Single-Molecule Electrical Conductance. [R] . Huang, G. 2015

机译：基于单分子电导的单分子DNa测序平台的研制。

Single-Molecule DNA Sequencing of a Viral Genome

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